Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia

Detalhes bibliográficos
Autor(a) principal: Sousa, Giovana Biasia De [UNIFESP]
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7748490
https://repositorio.unifesp.br/handle/11600/59114
Resumo: Introduction: Pancreatic pseudocyst refers specifically to a fluid collection in the peripancreatic tissues that it surrounded by a well defined wall and contains essentially no solid material. It has been successfully treated by EUS-guided drainage using different stents. Aims: to evaluate the safety and efficacy of EUS-guided pancreatic pseudocyst drainage using plastic double-pigtail stents in a tertiary hospital. Patients and Methods: we reviewed the results of 9 patients (median age 42 years [range: 14 – 79]; 67% male) with symptomatic pancreatic pseudocyst. Indication EUS-guided drainage was abdominal pain (8), gastric outlet obstruction (4) and biliary obstruction (1). The etiology was acute pancreatitis (4), chronic pancreatitis (3) and blunt abdominal trauma (2). Pseudocyst mean size was 9,8cm (range 5,3-13,5cm). Only patients presenting pancreatic pseudocyst according to The Revised Atlanta Classification were included in this study. Pseudocysts were treated with EUS-guided cystogastrostomy (8) and cystoduodenostomy (1). Overall recorded outcomes were technical success rate, clinical success rate, minor and major adverse events, mortality and recurrence. The criterion for stent removal was pseudocyst resolution on computed tomography scan. Results: Technical success rate was 100% (6 patients with 2 double-pigtail plastic stents and 3 patients with only one double-pigtail plastic stent). Overall clinical success and image pseudocyst resolution 4 – 6 months after initial drainage was 89% (8/9). Minor adverse events occurred in 3/9 patients (33%): false guidewire path with no clinical consequence, early stent migration and stent occlusion. There were no major events adverses. There was a recurrence in (1/9 patients) and no mortality. Conclusions: We concluded that EUS-guided transmural drainage of pancreatic pseudocyst using plastic double-pigtail stents is a safe procedure, resulting in clinical improvement and pseudocyst resolution in most of the patients.
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spelling Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopiaEfficacy and complications of EUS guided drainage of pancreatic pseudocystPancreatic PseudocystDrainageEndoscopyEndosonographyPseudocisto PancreáticoDrenagemEndoscopiaEndossonografiaIntroduction: Pancreatic pseudocyst refers specifically to a fluid collection in the peripancreatic tissues that it surrounded by a well defined wall and contains essentially no solid material. It has been successfully treated by EUS-guided drainage using different stents. Aims: to evaluate the safety and efficacy of EUS-guided pancreatic pseudocyst drainage using plastic double-pigtail stents in a tertiary hospital. Patients and Methods: we reviewed the results of 9 patients (median age 42 years [range: 14 – 79]; 67% male) with symptomatic pancreatic pseudocyst. Indication EUS-guided drainage was abdominal pain (8), gastric outlet obstruction (4) and biliary obstruction (1). The etiology was acute pancreatitis (4), chronic pancreatitis (3) and blunt abdominal trauma (2). Pseudocyst mean size was 9,8cm (range 5,3-13,5cm). Only patients presenting pancreatic pseudocyst according to The Revised Atlanta Classification were included in this study. Pseudocysts were treated with EUS-guided cystogastrostomy (8) and cystoduodenostomy (1). Overall recorded outcomes were technical success rate, clinical success rate, minor and major adverse events, mortality and recurrence. The criterion for stent removal was pseudocyst resolution on computed tomography scan. Results: Technical success rate was 100% (6 patients with 2 double-pigtail plastic stents and 3 patients with only one double-pigtail plastic stent). Overall clinical success and image pseudocyst resolution 4 – 6 months after initial drainage was 89% (8/9). Minor adverse events occurred in 3/9 patients (33%): false guidewire path with no clinical consequence, early stent migration and stent occlusion. There were no major events adverses. There was a recurrence in (1/9 patients) and no mortality. Conclusions: We concluded that EUS-guided transmural drainage of pancreatic pseudocyst using plastic double-pigtail stents is a safe procedure, resulting in clinical improvement and pseudocyst resolution in most of the patients.Introdução: Pseudocisto pancreático (PC) é definido como coleção líquida pancreática e peripancreática rica em amilase, sem necrose, que persiste por mais de 4 semanas. A drenagem é indicada em pacientes sintomáticos ou quando há crescimento progressivo. Drenagem endoscópica guiada por ecoendoscopia (drenagem ecoguiada) com diferentes próteses apresentam altas taxas de resolução. Objetivos: Avaliar segurança e eficácia da drenagem ecoguiada de pseudocisto pancreático com próteses plásticas duplo pigtail. Métodos: Avaliamos os resultados da drenagem ecoguiada em 9 pacientes (mediana de 42 [variou de 14-79], 67% gênero masculino) submetidos ao procedimento em hospital terciário. Indicações para drenagem foram: dor abdominal (8), obstrução gastroduodenal (5) e obstrução biliar (1). Etiologia dos pseudocistos: pancreatite aguda (4), pancreatite crônica (3) e trauma abdominal fechado (2). Tamanho médio do PC foi 9,8cm (medidas entre 5,3 e 13,5cm). Todos os pacientes se enquadravam nos critérios revisados da Classificação de Atlanta-2012. As vias de drenagem foram: cistogastrostomia (8) e cistoduodenostomia (1). Avaliamos sucesso técnico (punção com passagem da prótese), sucesso clínico (resolução do pseudocisto pancreático), complicações, mortalidade e recorrência. Critério para remoção das próteses foi a resolução do pseudocisto pancreático em tomografia computadorizada de abdome. Resultados: Sucesso técnico ocorreu em 100% (6 pacientes com duas próteses plásticas e três pacientes com apenas uma prótese). A taxa de sucesso clínico foi de 89% (8/9) observada em acompanhamento ambulatorial e exame de imagem de controle 2-6 meses após o procedimento. Complicações menores ocorreram em 3/9 pacientes (33%): falso trajeto do fio guia sem consequências clínicas, migração precoce e oclusão da prótese. Não houve complicações maiores. Ocorreu recorrência em 1/9 pacientes (11%), e nenhum óbito. Conclusão: A drenagem ecoguiada com próteses plásticas duplo pigtail, é segura e eficaz, com resolução do pseudocisto na maioria dos pacientes.Dados abertos - Sucupira - Teses e dissertações (2019)Universidade Federal de São Paulo (UNIFESP)Libera Junior, Ermelindo Della [UNIFESP]Nakao, Frank Shigueo [UNIFESP]http://lattes.cnpq.br/8755026089314875http://lattes.cnpq.br/0528784228011000http://lattes.cnpq.br/8684478554601684Universidade Federal de São Paulo (UNIFESP)Sousa, Giovana Biasia De [UNIFESP]2021-01-19T16:31:34Z2021-01-19T16:31:34Z2019-05-30info:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/publishedVersion64 f.application/pdfhttps://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7748490SOUSA, Giovana Biasia. Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por endoscopia. 2019.64f. Dissertação (Mestrado em Gastroenterologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.Giovana Biasia de Sousa-A.pdfhttps://repositorio.unifesp.br/handle/11600/59114porSão Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-10T18:59:44Zoai:repositorio.unifesp.br/:11600/59114Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-10T18:59:44Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
Efficacy and complications of EUS guided drainage of pancreatic pseudocyst
title Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
spellingShingle Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
Sousa, Giovana Biasia De [UNIFESP]
Pancreatic Pseudocyst
Drainage
Endoscopy
Endosonography
Pseudocisto Pancreático
Drenagem
Endoscopia
Endossonografia
title_short Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
title_full Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
title_fullStr Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
title_full_unstemmed Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
title_sort Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por ecoendoscopia
author Sousa, Giovana Biasia De [UNIFESP]
author_facet Sousa, Giovana Biasia De [UNIFESP]
author_role author
dc.contributor.none.fl_str_mv Libera Junior, Ermelindo Della [UNIFESP]
Nakao, Frank Shigueo [UNIFESP]
http://lattes.cnpq.br/8755026089314875
http://lattes.cnpq.br/0528784228011000
http://lattes.cnpq.br/8684478554601684
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Sousa, Giovana Biasia De [UNIFESP]
dc.subject.por.fl_str_mv Pancreatic Pseudocyst
Drainage
Endoscopy
Endosonography
Pseudocisto Pancreático
Drenagem
Endoscopia
Endossonografia
topic Pancreatic Pseudocyst
Drainage
Endoscopy
Endosonography
Pseudocisto Pancreático
Drenagem
Endoscopia
Endossonografia
description Introduction: Pancreatic pseudocyst refers specifically to a fluid collection in the peripancreatic tissues that it surrounded by a well defined wall and contains essentially no solid material. It has been successfully treated by EUS-guided drainage using different stents. Aims: to evaluate the safety and efficacy of EUS-guided pancreatic pseudocyst drainage using plastic double-pigtail stents in a tertiary hospital. Patients and Methods: we reviewed the results of 9 patients (median age 42 years [range: 14 – 79]; 67% male) with symptomatic pancreatic pseudocyst. Indication EUS-guided drainage was abdominal pain (8), gastric outlet obstruction (4) and biliary obstruction (1). The etiology was acute pancreatitis (4), chronic pancreatitis (3) and blunt abdominal trauma (2). Pseudocyst mean size was 9,8cm (range 5,3-13,5cm). Only patients presenting pancreatic pseudocyst according to The Revised Atlanta Classification were included in this study. Pseudocysts were treated with EUS-guided cystogastrostomy (8) and cystoduodenostomy (1). Overall recorded outcomes were technical success rate, clinical success rate, minor and major adverse events, mortality and recurrence. The criterion for stent removal was pseudocyst resolution on computed tomography scan. Results: Technical success rate was 100% (6 patients with 2 double-pigtail plastic stents and 3 patients with only one double-pigtail plastic stent). Overall clinical success and image pseudocyst resolution 4 – 6 months after initial drainage was 89% (8/9). Minor adverse events occurred in 3/9 patients (33%): false guidewire path with no clinical consequence, early stent migration and stent occlusion. There were no major events adverses. There was a recurrence in (1/9 patients) and no mortality. Conclusions: We concluded that EUS-guided transmural drainage of pancreatic pseudocyst using plastic double-pigtail stents is a safe procedure, resulting in clinical improvement and pseudocyst resolution in most of the patients.
publishDate 2019
dc.date.none.fl_str_mv 2019-05-30
2021-01-19T16:31:34Z
2021-01-19T16:31:34Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7748490
SOUSA, Giovana Biasia. Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por endoscopia. 2019.64f. Dissertação (Mestrado em Gastroenterologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
Giovana Biasia de Sousa-A.pdf
https://repositorio.unifesp.br/handle/11600/59114
url https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7748490
https://repositorio.unifesp.br/handle/11600/59114
identifier_str_mv SOUSA, Giovana Biasia. Eficácia e complicações da drenagem de pseudocistos de pâncreas guiada por endoscopia. 2019.64f. Dissertação (Mestrado em Gastroenterologia) – Escola Paulista de Medicina, Universidade Federal de São Paulo. São Paulo, 2019.
Giovana Biasia de Sousa-A.pdf
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 64 f.
application/pdf
dc.coverage.none.fl_str_mv São Paulo
dc.publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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