Desenvolvimento de uma ferramenta para auxílio na avaliação de lesões cartilaginosas do joelho

• Autor(a) principal: Jornada, Tiago da Silva [UNIFESP]
• Data de Publicação: 2017
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5774386; http://repositorio.unifesp.br/handle/11600/50118
• topic: Cartilage; Relaxometry; T2 maps; Matlab; Knee; Magnetic resonance imaging; Cartilagem; Relaxometria; Mapas T matlab; Joelho; Ressonância magnética

Introduction: T2 maps are commonly used in the evaluation and diagnosis of cartilaginous regions of the knee. When cartilage is preserved, collagen impairs the mobility of water, resulting in a lower T2 value when compared to that of non-preserved cartilage. However, when this structure is weakened, the water flow is higher, causing an increase in the values ​​for T2. In this way, the T2 maps present the analysis of the cartilage content in an indirect way, through Magnetic Resonance Imaging (MRI). However, for the study of T2 relaxometry it is necessary to acquire an MRI with single-echo or multi-echo protocols and post-process it with specific software. The main obstacle is that the programs available on the market require a high financial investment. Objective: To develop software that provides T2 Maps. Methods: By means of magnetic resonance imaging of 1.5 T, we obtained MRI from seven patients and developed software in MATLAB to generate T2 maps. Finally, we compare the results obtained with three free programs that have the same purpose. Results: We developed software and named it T2 Maps. We compared the results obtained with three free programs, however, two of them did not allow a more careful analysis of the cartilaginous regions of the knee. In contrast, when the comparative study was possible, there was no significant difference between the values ​​of the T2 maps. Conclusion: The objective proposed in this paper was reached. The software that will be made available to the academic and professional environment allows us to generate the T2 maps of the cartilaginous structures of the knee in an agile way, with usability features that differentiate it from the other programs tested in the present study.