Acidóse tubular renal distal manifestando-se com rabdomiólise
Autor(a) principal: | |
---|---|
Data de Publicação: | 1994 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0004-282X1994000400016 http://repositorio.unifesp.br/handle/11600/360 |
Resumo: | Severe hypokalemia is an uncommon cause of rhabdomyolysis. We describe a patient, 28-year-old woman, with distal renal tubular acidosis (DRTA) who developed severe hypokalemia and rhabdomyolysis. Muscle biopsy shows focal muscular necrosis mainly in type II muscle fibers and mild macrophagic reaction. After correcting the acidosis with oral administration of alkalinizing salts, clinical and laboratory improvement was seen. This clearly establish a causal realtionship between the positive acid balance, hypokalemia and the muscular manifestation in DRTA. |
id |
UFSP_c1b6c8bd79928a8c2ef179805d334ff4 |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br/:11600/360 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Acidóse tubular renal distal manifestando-se com rabdomióliseDistail renal tubular acidosis manifesting with rhabdomyolysishypokalemiarhabdomyolysisrenal tubular acidosishipocalemiarabdomióliseacidóse tubular renalSevere hypokalemia is an uncommon cause of rhabdomyolysis. We describe a patient, 28-year-old woman, with distal renal tubular acidosis (DRTA) who developed severe hypokalemia and rhabdomyolysis. Muscle biopsy shows focal muscular necrosis mainly in type II muscle fibers and mild macrophagic reaction. After correcting the acidosis with oral administration of alkalinizing salts, clinical and laboratory improvement was seen. This clearly establish a causal realtionship between the positive acid balance, hypokalemia and the muscular manifestation in DRTA.A hipocalemia severa é causa incomum de rabdomiólise. Descreve-se o caso de urna paciente de 28 anos com acidóse tubular renal distal, que desenvolveu hipocalemia severa com consequente rabdomiólise. O estudo histológico do músculo evidenciou áreas focais de necrose muscular predominando em fibras do tipo II, com discreta reação macrofágica. A melhora clínica e laboratorial apresentada pela paciente ocorreu após a normalização do potássio sérico, tendo sido fundamental, neste caso, a correção da acidóse metabólica.Escola Paulista de Medicina Departamento de Neurologia, Neurocirurgia e Neurologia ExperimentalEPM Departamento de Anatomia PatológicaUNIFESP, EPM, Depto. de Neurologia, Neurocirurgia e Neurologia ExperimentalEPM Depto. de Anatomia PatológicaSciELOAcademia Brasileira de Neurologia - ABNEUROUniversidade Federal de São Paulo (UNIFESP)Zanoteli, Edmar [UNIFESP]Oliveira, Acary Souza Bulle [UNIFESP]Tengan, Célia Harumi [UNIFESP]Morita, Maria da Penha Ananias [UNIFESP]Schmidt, Beny [UNIFESP]Gabbai, Alberto Alain [UNIFESP]2015-06-14T13:24:27Z2015-06-14T13:24:27Z1994-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion549-553application/pdfhttp://dx.doi.org/10.1590/S0004-282X1994000400016Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 4, p. 549-553, 1994.10.1590/S0004-282X1994000400016S0004-282X1994000400016.pdf0004-282XS0004-282X1994000400016http://repositorio.unifesp.br/handle/11600/360porArquivos de Neuro-Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T12:32:24Zoai:repositorio.unifesp.br/:11600/360Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-28T12:32:24Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Acidóse tubular renal distal manifestando-se com rabdomiólise Distail renal tubular acidosis manifesting with rhabdomyolysis |
title |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
spellingShingle |
Acidóse tubular renal distal manifestando-se com rabdomiólise Zanoteli, Edmar [UNIFESP] hypokalemia rhabdomyolysis renal tubular acidosis hipocalemia rabdomiólise acidóse tubular renal |
title_short |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
title_full |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
title_fullStr |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
title_full_unstemmed |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
title_sort |
Acidóse tubular renal distal manifestando-se com rabdomiólise |
author |
Zanoteli, Edmar [UNIFESP] |
author_facet |
Zanoteli, Edmar [UNIFESP] Oliveira, Acary Souza Bulle [UNIFESP] Tengan, Célia Harumi [UNIFESP] Morita, Maria da Penha Ananias [UNIFESP] Schmidt, Beny [UNIFESP] Gabbai, Alberto Alain [UNIFESP] |
author_role |
author |
author2 |
Oliveira, Acary Souza Bulle [UNIFESP] Tengan, Célia Harumi [UNIFESP] Morita, Maria da Penha Ananias [UNIFESP] Schmidt, Beny [UNIFESP] Gabbai, Alberto Alain [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Zanoteli, Edmar [UNIFESP] Oliveira, Acary Souza Bulle [UNIFESP] Tengan, Célia Harumi [UNIFESP] Morita, Maria da Penha Ananias [UNIFESP] Schmidt, Beny [UNIFESP] Gabbai, Alberto Alain [UNIFESP] |
dc.subject.por.fl_str_mv |
hypokalemia rhabdomyolysis renal tubular acidosis hipocalemia rabdomiólise acidóse tubular renal |
topic |
hypokalemia rhabdomyolysis renal tubular acidosis hipocalemia rabdomiólise acidóse tubular renal |
description |
Severe hypokalemia is an uncommon cause of rhabdomyolysis. We describe a patient, 28-year-old woman, with distal renal tubular acidosis (DRTA) who developed severe hypokalemia and rhabdomyolysis. Muscle biopsy shows focal muscular necrosis mainly in type II muscle fibers and mild macrophagic reaction. After correcting the acidosis with oral administration of alkalinizing salts, clinical and laboratory improvement was seen. This clearly establish a causal realtionship between the positive acid balance, hypokalemia and the muscular manifestation in DRTA. |
publishDate |
1994 |
dc.date.none.fl_str_mv |
1994-12-01 2015-06-14T13:24:27Z 2015-06-14T13:24:27Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0004-282X1994000400016 Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 4, p. 549-553, 1994. 10.1590/S0004-282X1994000400016 S0004-282X1994000400016.pdf 0004-282X S0004-282X1994000400016 http://repositorio.unifesp.br/handle/11600/360 |
url |
http://dx.doi.org/10.1590/S0004-282X1994000400016 http://repositorio.unifesp.br/handle/11600/360 |
identifier_str_mv |
Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 52, n. 4, p. 549-553, 1994. 10.1590/S0004-282X1994000400016 S0004-282X1994000400016.pdf 0004-282X S0004-282X1994000400016 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Arquivos de Neuro-Psiquiatria |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
549-553 application/pdf |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
publisher.none.fl_str_mv |
Academia Brasileira de Neurologia - ABNEURO |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268416071041024 |