Methods for the assessment of opioid-induced hyperalgesia in the perioperative period

Detalhes bibliográficos
Autor(a) principal: Leal, Plínio da Cunha [UNIFESP]
Data de Publicação: 2014
Outros Autores: Sakata, Rioko Kimiko [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.5935/1806-0013.20140064
http://repositorio.unifesp.br/handle/11600/8698
Resumo: BACKGROUND AND OBJECTIVES: Opioid-induced hyperalgesia is a topic not yet fully understood in terms of mechanisms, diagnosis, prevention and treatment. Thus, it seems of great importance to evaluate this phenomenon that negatively affects the treatment of pain. The purpose of this study was to describe what tools to use to evaluate perioperative hyperalgesia. CONTENTS: Several methods have been suggested to evaluate opioid-induced hyperalgesia, such as measure of pain intensity, opioid consumption, and evaluation of secondary hyperalgesia with algometer and Von Frey monofilaments. The measurement of some substances, such as cytokines, glutamate, and dynorphin has also been used. CONCLUSION: There are several ways to evaluate opioidinduced hiperalgesia, easily reproducible tests should be chosen and which have also been described in previous studies.
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spelling Methods for the assessment of opioid-induced hyperalgesia in the perioperative periodMétodos para a avaliação da hiperalgesia induzida por opioides no período perioperatórioAnalgesic opioidEvaluationHyperalgesiaPainAnalgésico opioideAvaliaçãoDorHiperalgesiaBACKGROUND AND OBJECTIVES: Opioid-induced hyperalgesia is a topic not yet fully understood in terms of mechanisms, diagnosis, prevention and treatment. Thus, it seems of great importance to evaluate this phenomenon that negatively affects the treatment of pain. The purpose of this study was to describe what tools to use to evaluate perioperative hyperalgesia. CONTENTS: Several methods have been suggested to evaluate opioid-induced hyperalgesia, such as measure of pain intensity, opioid consumption, and evaluation of secondary hyperalgesia with algometer and Von Frey monofilaments. The measurement of some substances, such as cytokines, glutamate, and dynorphin has also been used. CONCLUSION: There are several ways to evaluate opioidinduced hiperalgesia, easily reproducible tests should be chosen and which have also been described in previous studies.JUSTIFICATIVA E OBJETIVOS: A hiperalgesia induzida pelo opioide é um tema ainda não totalmente esclarecido do ponto de vista dos mecanismos, do diagnóstico, da prevenção e do tratamento. Assim, parece de grande importância a avaliação desse fenômeno que afeta de maneira negativa o tratamento da dor. O objetivo deste estudo foi descrever quais instrumentos utilizar para avaliar a hiperalgesia perioperatória. CONTEÚDO: Vários métodos têm sido indicados para avaliar hiperalgesia induzida pelo opioide, tais como medida da intensidade da dor, consumo de opioide, e avaliação da hiperalgesia secundária com algômetro e monofilamentos de Von Frey. A dosagem de certas substâncias, como citocinas, glutamato e dinorfina, também tem sido utilizada. CONCLUSÃO: Existem diversas maneiras de avaliar a hiperalgesia induzida pelo opioide; portanto devem ser escolhidos testes de fácil reprodutibilidade e que também foram descritos em estudos anteriores.Hospital São Domingos Department of Anesthesiology Pain SectorFederal University of São PauloUNIFESP, EPMSciELOSociedade Brasileira para o Estudo da DorHospital São Domingos Department of Anesthesiology Pain SectorUniversidade Federal de São Paulo (UNIFESP)Leal, Plínio da Cunha [UNIFESP]Sakata, Rioko Kimiko [UNIFESP]2015-06-14T13:47:25Z2015-06-14T13:47:25Z2014-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion296-299application/pdfhttp://dx.doi.org/10.5935/1806-0013.20140064Revista Dor. Sociedade Brasileira para o Estudo da Dor, v. 15, n. 4, p. 296-299, 2014.10.5935/1806-0013.20140064S1806-00132014000400296.pdf1806-0013S1806-00132014000400296http://repositorio.unifesp.br/handle/11600/8698engRevista Dorinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T09:27:35Zoai:repositorio.unifesp.br/:11600/8698Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T09:27:35Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
Métodos para a avaliação da hiperalgesia induzida por opioides no período perioperatório
title Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
spellingShingle Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
Leal, Plínio da Cunha [UNIFESP]
Analgesic opioid
Evaluation
Hyperalgesia
Pain
Analgésico opioide
Avaliação
Dor
Hiperalgesia
title_short Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
title_full Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
title_fullStr Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
title_full_unstemmed Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
title_sort Methods for the assessment of opioid-induced hyperalgesia in the perioperative period
author Leal, Plínio da Cunha [UNIFESP]
author_facet Leal, Plínio da Cunha [UNIFESP]
Sakata, Rioko Kimiko [UNIFESP]
author_role author
author2 Sakata, Rioko Kimiko [UNIFESP]
author2_role author
dc.contributor.none.fl_str_mv Hospital São Domingos Department of Anesthesiology Pain Sector
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Leal, Plínio da Cunha [UNIFESP]
Sakata, Rioko Kimiko [UNIFESP]
dc.subject.por.fl_str_mv Analgesic opioid
Evaluation
Hyperalgesia
Pain
Analgésico opioide
Avaliação
Dor
Hiperalgesia
topic Analgesic opioid
Evaluation
Hyperalgesia
Pain
Analgésico opioide
Avaliação
Dor
Hiperalgesia
description BACKGROUND AND OBJECTIVES: Opioid-induced hyperalgesia is a topic not yet fully understood in terms of mechanisms, diagnosis, prevention and treatment. Thus, it seems of great importance to evaluate this phenomenon that negatively affects the treatment of pain. The purpose of this study was to describe what tools to use to evaluate perioperative hyperalgesia. CONTENTS: Several methods have been suggested to evaluate opioid-induced hyperalgesia, such as measure of pain intensity, opioid consumption, and evaluation of secondary hyperalgesia with algometer and Von Frey monofilaments. The measurement of some substances, such as cytokines, glutamate, and dynorphin has also been used. CONCLUSION: There are several ways to evaluate opioidinduced hiperalgesia, easily reproducible tests should be chosen and which have also been described in previous studies.
publishDate 2014
dc.date.none.fl_str_mv 2014-12-01
2015-06-14T13:47:25Z
2015-06-14T13:47:25Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5935/1806-0013.20140064
Revista Dor. Sociedade Brasileira para o Estudo da Dor, v. 15, n. 4, p. 296-299, 2014.
10.5935/1806-0013.20140064
S1806-00132014000400296.pdf
1806-0013
S1806-00132014000400296
http://repositorio.unifesp.br/handle/11600/8698
url http://dx.doi.org/10.5935/1806-0013.20140064
http://repositorio.unifesp.br/handle/11600/8698
identifier_str_mv Revista Dor. Sociedade Brasileira para o Estudo da Dor, v. 15, n. 4, p. 296-299, 2014.
10.5935/1806-0013.20140064
S1806-00132014000400296.pdf
1806-0013
S1806-00132014000400296
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Dor
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 296-299
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Estudo da Dor
publisher.none.fl_str_mv Sociedade Brasileira para o Estudo da Dor
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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