Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães

Detalhes bibliográficos
Autor(a) principal: Prado Filho, Orlando Ribeiro
Data de Publicação: 2004
Outros Autores: Fagundes, Djalma José [UNIFESP], Nigro, Amaury José Teixeira [UNIFESP], Bandeira, César Orlando Peralta, Novo, Neil Ferreira [UNIFESP], Juliano, Yara [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0100-69912004000400003
http://repositorio.unifesp.br/handle/11600/2184
Resumo: BACKGROUND: The aim of this research was to study the effects of the use of fibrin adhesive with the surgical technique of submucosa invagination, in esophageal anastomosis. METHODS: Thirty two dogs operated on for esophageal anastomosis, were distributed in two groups: group I with encircling suture of twelve stitches, and group II with encircling suture of four stitches and fibrin sealant. The anastomosis was evaluated in the 7th and 14th post-operative day. Weight evolution, stenosis rate, presence of dehiscence and fistulae, presence of secretion around the anastomosis, presence of interstitial liquid, protean matrix, number of cells, fibroblasts, collagen fibers and the hydroxyproline concentration in the anastomosis were analysed. RESULTS: The stenosis rate was lower in the group I in the 7th post-operative day. The incidence of fistulae was significant in group II on the 7th day, as well as the presence of dehiscence, serosa secretion and suppurative secretion at the 7th and 14th day. Concerning hydroxyproline tissue concentration there was no statistical difference among the groups. The fibroblasts and collagen fibers were more numerous in group II at 14th day. There were four deaths in animals of group II. CONCLUSION: We concluded that anastomosis performed by submucosa-mucosa invagination with fibrin adhesive presented results less satisfactory than anastomosis performed with twelve encircling stitches.
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spelling Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cãesThe use of fibrin adhesive in the esophagus-esophageal cervical anastomosis, in dogsDogsEsophagusFibrin adhesiveSurgical anastomosisAnastomose CirúrgicaCãesAdesivo de FibrinaEsôfagoBACKGROUND: The aim of this research was to study the effects of the use of fibrin adhesive with the surgical technique of submucosa invagination, in esophageal anastomosis. METHODS: Thirty two dogs operated on for esophageal anastomosis, were distributed in two groups: group I with encircling suture of twelve stitches, and group II with encircling suture of four stitches and fibrin sealant. The anastomosis was evaluated in the 7th and 14th post-operative day. Weight evolution, stenosis rate, presence of dehiscence and fistulae, presence of secretion around the anastomosis, presence of interstitial liquid, protean matrix, number of cells, fibroblasts, collagen fibers and the hydroxyproline concentration in the anastomosis were analysed. RESULTS: The stenosis rate was lower in the group I in the 7th post-operative day. The incidence of fistulae was significant in group II on the 7th day, as well as the presence of dehiscence, serosa secretion and suppurative secretion at the 7th and 14th day. Concerning hydroxyproline tissue concentration there was no statistical difference among the groups. The fibroblasts and collagen fibers were more numerous in group II at 14th day. There were four deaths in animals of group II. CONCLUSION: We concluded that anastomosis performed by submucosa-mucosa invagination with fibrin adhesive presented results less satisfactory than anastomosis performed with twelve encircling stitches.OBJETIVO: Estudar os efeitos da associação do adesivo cirúrgico de fibrina à técnica operatória da invaginação submucosa, em anastomoses esofagianas. MÉTODO: Trinta e dois cães submetidos à anastomose esôfago-esofágica foram alocados em dois grupos: I com sutura em doze pontos e II com sutura em quatro pontos e vedação com adesivo de fibrina. Os animais foram avaliados no sétimo e décimo-quarto dias de pós-operatório. Foram analisados: a evolução ponderal, o índice de estenose, a incidência de deiscências e fístulas, a presença de secreções na tela subcutânea, a presença de líquido intersticial, matriz protêica, celularidade, fibroblastos, fibras de colágeno e concentração de hidroxiprolina. RESULTADOS: O índice de estenose foi menor para os animais do grupo I no sétimo dia de observação. Nos animais do grupo II a incidência de deiscências, secreção serosa e purulenta foram signitivamente maiores aos sete e quatorze dias, enquanto a presença de fístulas foi maior no sétimo dia. Quanto à concentração tecidual de hidroxiprolina não houve diferença estatística entre os grupos. Os fibroblastos e fibras de colágeno tiveram presença mais acentuada no grupo II no décimo-quarto dia. Ocorreram quatro óbitos em animais do grupo II. CONCLUSÕES: A anastomose por invaginação submucosa-mucosa com vedação com adesivo de fibrina apresentou piores resultados que a anastomose convencional de doze pontos circunferenciais.Universidade Estadual de Maringá Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de CirurgiaUNIFESP-EPM Departamento de Medicina PreventivaUNIFESP, EPM, Depto. de CirurgiaUNIFESP, EPM Depto. de Medicina PreventivaSciELOColégio Brasileiro de CirurgiõesUniversidade Estadual de Maringá Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP)Prado Filho, Orlando RibeiroFagundes, Djalma José [UNIFESP]Nigro, Amaury José Teixeira [UNIFESP]Bandeira, César Orlando PeraltaNovo, Neil Ferreira [UNIFESP]Juliano, Yara [UNIFESP]2015-06-14T13:31:13Z2015-06-14T13:31:13Z2004-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion228-232application/pdfhttp://dx.doi.org/10.1590/S0100-69912004000400003Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 31, n. 4, p. 228-232, 2004.10.1590/S0100-69912004000400003S0100-69912004000400003.pdf0100-6991S0100-69912004000400003http://repositorio.unifesp.br/handle/11600/2184porRevista do Colégio Brasileiro de Cirurgiõesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T07:33:20Zoai:repositorio.unifesp.br/:11600/2184Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-28T07:33:20Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
The use of fibrin adhesive in the esophagus-esophageal cervical anastomosis, in dogs
title Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
spellingShingle Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
Prado Filho, Orlando Ribeiro
Dogs
Esophagus
Fibrin adhesive
Surgical anastomosis
Anastomose Cirúrgica
Cães
Adesivo de Fibrina
Esôfago
title_short Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
title_full Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
title_fullStr Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
title_full_unstemmed Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
title_sort Uso do adesivo de fibrina na anastomose esôfago-esofágica cervical, em cães
author Prado Filho, Orlando Ribeiro
author_facet Prado Filho, Orlando Ribeiro
Fagundes, Djalma José [UNIFESP]
Nigro, Amaury José Teixeira [UNIFESP]
Bandeira, César Orlando Peralta
Novo, Neil Ferreira [UNIFESP]
Juliano, Yara [UNIFESP]
author_role author
author2 Fagundes, Djalma José [UNIFESP]
Nigro, Amaury José Teixeira [UNIFESP]
Bandeira, César Orlando Peralta
Novo, Neil Ferreira [UNIFESP]
Juliano, Yara [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual de Maringá Departamento de Medicina
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Prado Filho, Orlando Ribeiro
Fagundes, Djalma José [UNIFESP]
Nigro, Amaury José Teixeira [UNIFESP]
Bandeira, César Orlando Peralta
Novo, Neil Ferreira [UNIFESP]
Juliano, Yara [UNIFESP]
dc.subject.por.fl_str_mv Dogs
Esophagus
Fibrin adhesive
Surgical anastomosis
Anastomose Cirúrgica
Cães
Adesivo de Fibrina
Esôfago
topic Dogs
Esophagus
Fibrin adhesive
Surgical anastomosis
Anastomose Cirúrgica
Cães
Adesivo de Fibrina
Esôfago
description BACKGROUND: The aim of this research was to study the effects of the use of fibrin adhesive with the surgical technique of submucosa invagination, in esophageal anastomosis. METHODS: Thirty two dogs operated on for esophageal anastomosis, were distributed in two groups: group I with encircling suture of twelve stitches, and group II with encircling suture of four stitches and fibrin sealant. The anastomosis was evaluated in the 7th and 14th post-operative day. Weight evolution, stenosis rate, presence of dehiscence and fistulae, presence of secretion around the anastomosis, presence of interstitial liquid, protean matrix, number of cells, fibroblasts, collagen fibers and the hydroxyproline concentration in the anastomosis were analysed. RESULTS: The stenosis rate was lower in the group I in the 7th post-operative day. The incidence of fistulae was significant in group II on the 7th day, as well as the presence of dehiscence, serosa secretion and suppurative secretion at the 7th and 14th day. Concerning hydroxyproline tissue concentration there was no statistical difference among the groups. The fibroblasts and collagen fibers were more numerous in group II at 14th day. There were four deaths in animals of group II. CONCLUSION: We concluded that anastomosis performed by submucosa-mucosa invagination with fibrin adhesive presented results less satisfactory than anastomosis performed with twelve encircling stitches.
publishDate 2004
dc.date.none.fl_str_mv 2004-08-01
2015-06-14T13:31:13Z
2015-06-14T13:31:13Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-69912004000400003
Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 31, n. 4, p. 228-232, 2004.
10.1590/S0100-69912004000400003
S0100-69912004000400003.pdf
0100-6991
S0100-69912004000400003
http://repositorio.unifesp.br/handle/11600/2184
url http://dx.doi.org/10.1590/S0100-69912004000400003
http://repositorio.unifesp.br/handle/11600/2184
identifier_str_mv Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 31, n. 4, p. 228-232, 2004.
10.1590/S0100-69912004000400003
S0100-69912004000400003.pdf
0100-6991
S0100-69912004000400003
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista do Colégio Brasileiro de Cirurgiões
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 228-232
application/pdf
dc.publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
publisher.none.fl_str_mv Colégio Brasileiro de Cirurgiões
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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