Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/8578 http://dx.doi.org/10.1055/s-0033-1364174 |
Resumo: | Introduction: Benign idiopathic tonsillar hypertrophy (HBI) may affect a child's quality of life and sleep. Several studies have sought to relate the clinical features of HBI with the infectious and/or immunologic changes that occur. Objective: To increase the knowledge of the etiology of HBI. Data Synthesis: From 2012 to 2013 we conducted a retrospective observational study of 101 children with HBI who underwent tonsillectomies at Ambulatory ENT General Hospital of the East Zone of São Paulo City, a region with a poor socioeconomic population. Preoperative serologic results were available to confirm mononucleosis, cytomegalovirus, anti-streptolysin O (ASLO) and immunoglobulins. The mean patient age was 5.8 years (55% male, 45% female). Using the Mann-Whitney U test, we identified significant gender differences in the parameters of immunoglobulins (Ig) M (IgM), IgA, and IgE. Forty-seven percent of the patients had increased ASLO levels, and 37% had increased IgE levels. Conclusion: An evaluation of a patient's serologic parameters and laboratory results may be relevant to the etiology and prevention of HBI. Based on the results obtained from the study sample, the identification of etiologic agents and causative factors remain a public health challenge that affects the quality of life of children. |
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Miramontes, Henrique PrestesFagundes, Djalma José [UNIFESP]Jurgielewicz, Julia Coelho Lima EMiramontes Neto, Haroldo PrestesOliveira, Renan Gianotto DeOliveira, Gustavo Gianotto DeSouza, Maria Rosa Machado DeUniversidade Anhembi MorumbiUniversidade Federal de São Paulo (UNIFESP)Universdidade Cidade de São Paulo2015-06-14T13:47:17Z2015-06-14T13:47:17Z2014-09-01International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 311-315, 2014.1809-4864http://repositorio.unifesp.br/handle/11600/8578http://dx.doi.org/10.1055/s-0033-1364174S1809-48642014000300311.pdfS1809-4864201400030031110.1055/s-0033-1364174Introduction: Benign idiopathic tonsillar hypertrophy (HBI) may affect a child's quality of life and sleep. Several studies have sought to relate the clinical features of HBI with the infectious and/or immunologic changes that occur. Objective: To increase the knowledge of the etiology of HBI. Data Synthesis: From 2012 to 2013 we conducted a retrospective observational study of 101 children with HBI who underwent tonsillectomies at Ambulatory ENT General Hospital of the East Zone of São Paulo City, a region with a poor socioeconomic population. Preoperative serologic results were available to confirm mononucleosis, cytomegalovirus, anti-streptolysin O (ASLO) and immunoglobulins. The mean patient age was 5.8 years (55% male, 45% female). Using the Mann-Whitney U test, we identified significant gender differences in the parameters of immunoglobulins (Ig) M (IgM), IgA, and IgE. Forty-seven percent of the patients had increased ASLO levels, and 37% had increased IgE levels. Conclusion: An evaluation of a patient's serologic parameters and laboratory results may be relevant to the etiology and prevention of HBI. Based on the results obtained from the study sample, the identification of etiologic agents and causative factors remain a public health challenge that affects the quality of life of children.Universidade Anhembi MorumbiUniversidade Federal de São Paulo (UNIFESP)Universdidade Cidade de São PauloUNIFESP, EPMSciELO311-315engFundação OtorrinolaringologiaInternational Archives of Otorhinolaryngologychildtonsillectomyimmunoglobulinsimmune systemPrevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1809-48642014000300311.pdfapplication/pdf579686${dspace.ui.url}/bitstream/11600/8578/1/S1809-48642014000300311.pdf1bee7c7faf617a2e08d5c0cc917c47b6MD51open accessTEXTS1809-48642014000300311.pdf.txtS1809-48642014000300311.pdf.txtExtracted texttext/plain19449${dspace.ui.url}/bitstream/11600/8578/2/S1809-48642014000300311.pdf.txt1d0181555e18a46c26115cafcc30a959MD52open access11600/85782022-06-02 09:12:58.703open accessoai:repositorio.unifesp.br:11600/8578Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-06-02T12:12:58Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
title |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
spellingShingle |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis Miramontes, Henrique Prestes child tonsillectomy immunoglobulins immune system |
title_short |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
title_full |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
title_fullStr |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
title_full_unstemmed |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
title_sort |
Prevalence of Microorganisms and Immunoglobulins in Children with Tonsillar Hypertrophy and Adenoiditis |
author |
Miramontes, Henrique Prestes |
author_facet |
Miramontes, Henrique Prestes Fagundes, Djalma José [UNIFESP] Jurgielewicz, Julia Coelho Lima E Miramontes Neto, Haroldo Prestes Oliveira, Renan Gianotto De Oliveira, Gustavo Gianotto De Souza, Maria Rosa Machado De |
author_role |
author |
author2 |
Fagundes, Djalma José [UNIFESP] Jurgielewicz, Julia Coelho Lima E Miramontes Neto, Haroldo Prestes Oliveira, Renan Gianotto De Oliveira, Gustavo Gianotto De Souza, Maria Rosa Machado De |
author2_role |
author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Anhembi Morumbi Universidade Federal de São Paulo (UNIFESP) Universdidade Cidade de São Paulo |
dc.contributor.author.fl_str_mv |
Miramontes, Henrique Prestes Fagundes, Djalma José [UNIFESP] Jurgielewicz, Julia Coelho Lima E Miramontes Neto, Haroldo Prestes Oliveira, Renan Gianotto De Oliveira, Gustavo Gianotto De Souza, Maria Rosa Machado De |
dc.subject.eng.fl_str_mv |
child tonsillectomy immunoglobulins immune system |
topic |
child tonsillectomy immunoglobulins immune system |
description |
Introduction: Benign idiopathic tonsillar hypertrophy (HBI) may affect a child's quality of life and sleep. Several studies have sought to relate the clinical features of HBI with the infectious and/or immunologic changes that occur. Objective: To increase the knowledge of the etiology of HBI. Data Synthesis: From 2012 to 2013 we conducted a retrospective observational study of 101 children with HBI who underwent tonsillectomies at Ambulatory ENT General Hospital of the East Zone of São Paulo City, a region with a poor socioeconomic population. Preoperative serologic results were available to confirm mononucleosis, cytomegalovirus, anti-streptolysin O (ASLO) and immunoglobulins. The mean patient age was 5.8 years (55% male, 45% female). Using the Mann-Whitney U test, we identified significant gender differences in the parameters of immunoglobulins (Ig) M (IgM), IgA, and IgE. Forty-seven percent of the patients had increased ASLO levels, and 37% had increased IgE levels. Conclusion: An evaluation of a patient's serologic parameters and laboratory results may be relevant to the etiology and prevention of HBI. Based on the results obtained from the study sample, the identification of etiologic agents and causative factors remain a public health challenge that affects the quality of life of children. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-09-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:47:17Z |
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2015-06-14T13:47:17Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 311-315, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/8578 http://dx.doi.org/10.1055/s-0033-1364174 |
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1809-4864 |
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S1809-48642014000300311.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1809-48642014000300311 |
dc.identifier.doi.none.fl_str_mv |
10.1055/s-0033-1364174 |
identifier_str_mv |
International Archives of Otorhinolaryngology. Fundação Otorrinolaringologia, v. 18, n. 3, p. 311-315, 2014. 1809-4864 S1809-48642014000300311.pdf S1809-48642014000300311 10.1055/s-0033-1364174 |
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http://repositorio.unifesp.br/handle/11600/8578 http://dx.doi.org/10.1055/s-0033-1364174 |
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eng |
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International Archives of Otorhinolaryngology |
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311-315 |
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Fundação Otorrinolaringologia |
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Fundação Otorrinolaringologia |
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