Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification

Detalhes bibliográficos
Autor(a) principal: Uellendahl, Marly [UNIFESP]
Data de Publicação: 2016
Outros Autores: Siqueira, Maria Eduarda Menezes de [UNIFESP], Calado, Eveline Barros [UNIFESP], Kalil-Filho, Roberto, Sobral, Dario, Ribeiro, Clebia, Oliveira, Wilson, Martins, Silvia, Narula, Jagat, Rochitte, Carlos Eduardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.5935/abc.20160168
https://repositorio.unifesp.br/handle/11600/56769
Resumo: Background: Chagas disease (CD) is an important cause of heart failure and mortality, mainly in Latin America. This study evaluated the morphological and functional characteristics of the heart as well the extent of myocardial fibrosis (MF) in patients with CD by cardiac magnetic resonance (CMR). The prognostic value of MF evaluated by myocardialdelayed enhancement (MDE) was compared with that via Rassi score. Methods: This study assessed 39 patients divided into 2 groups: 28 asymptomatic patients as indeterminate form group (IND)
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spelling Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk StratificationChagas CardiomyopathyChagas DiseaseMagnetic Resonance SpectroscopyRisk factorsPrognosisBackground: Chagas disease (CD) is an important cause of heart failure and mortality, mainly in Latin America. This study evaluated the morphological and functional characteristics of the heart as well the extent of myocardial fibrosis (MF) in patients with CD by cardiac magnetic resonance (CMR). The prognostic value of MF evaluated by myocardialdelayed enhancement (MDE) was compared with that via Rassi score. Methods: This study assessed 39 patients divided into 2 groups: 28 asymptomatic patients as indeterminate form group (IND)and symptomatic patients as Chagas Heart Disease (CHD) group. All patients underwent CMR using the techniques of cine-MRI and MDE, and the amount of MF was compared with the Rassi score. Results: Regarding the morphological and functional analysis, significant differences were observed between both groups (p < 0.001). Furthermore, there was a strong correlation between the extent of MF and the Rassi score (r = 0.76). Conclusions: CMR is an important technique for evaluating patients with CD, stressing morphological and functional differences in all clinical presentations. The strong correlation with the Rassi score and the extent of MF detected by CMR emphasizes its role in the prognostic stratification of patients with CD.Univ Sao Paulo, Fac Med, Inst Coracao InCor, Setor Ressonancia Magnet Cardiovasc, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, UNIFESP EPM, Setor Ressonancia Magnet Cardiaca, Sao Paulo, SP, BrazilDASA Delboni, Sao Paulo, SP, BrazilUniv Pernambuco, Hosp Oswaldo Cruz, Dept Cardiol, Recife, PE, BrazilMt Sinai Hosp, Dept Cardiol, New York, NY 10029 USASetor de Ressonância Magnética Cardíaca - Universidade Federal de São Paulo (UNIFESP/EPM)Web of ScienceArquivos Brasileiros Cardiologia2020-07-31T12:47:21Z2020-07-31T12:47:21Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion460-466http://dx.doi.org/10.5935/abc.20160168Arquivos Brasileiros De Cardiologia. Rio De Janeiro, v. 107, n. 5, p. 460-466, 2016.10.5935/abc.201601680066-782Xhttps://repositorio.unifesp.br/handle/11600/56769WOS:000391430900009engArquivos Brasileiros De CardiologiaRio De Janeiroinfo:eu-repo/semantics/openAccessUellendahl, Marly [UNIFESP]Siqueira, Maria Eduarda Menezes de [UNIFESP]Calado, Eveline Barros [UNIFESP]Kalil-Filho, RobertoSobral, DarioRibeiro, ClebiaOliveira, WilsonMartins, SilviaNarula, JagatRochitte, Carlos Eduardoreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-08T12:05:22Zoai:repositorio.unifesp.br/:11600/56769Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652022-02-08T12:05:22Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
title Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
spellingShingle Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
Uellendahl, Marly [UNIFESP]
Chagas Cardiomyopathy
Chagas Disease
Magnetic Resonance Spectroscopy
Risk factors
Prognosis
title_short Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
title_full Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
title_fullStr Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
title_full_unstemmed Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
title_sort Cardiac Magnetic Resonance-Verified Myocardial Fibrosis in Chagas Disease: Clinical Correlates and Risk Stratification
author Uellendahl, Marly [UNIFESP]
author_facet Uellendahl, Marly [UNIFESP]
Siqueira, Maria Eduarda Menezes de [UNIFESP]
Calado, Eveline Barros [UNIFESP]
Kalil-Filho, Roberto
Sobral, Dario
Ribeiro, Clebia
Oliveira, Wilson
Martins, Silvia
Narula, Jagat
Rochitte, Carlos Eduardo
author_role author
author2 Siqueira, Maria Eduarda Menezes de [UNIFESP]
Calado, Eveline Barros [UNIFESP]
Kalil-Filho, Roberto
Sobral, Dario
Ribeiro, Clebia
Oliveira, Wilson
Martins, Silvia
Narula, Jagat
Rochitte, Carlos Eduardo
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Uellendahl, Marly [UNIFESP]
Siqueira, Maria Eduarda Menezes de [UNIFESP]
Calado, Eveline Barros [UNIFESP]
Kalil-Filho, Roberto
Sobral, Dario
Ribeiro, Clebia
Oliveira, Wilson
Martins, Silvia
Narula, Jagat
Rochitte, Carlos Eduardo
dc.subject.por.fl_str_mv Chagas Cardiomyopathy
Chagas Disease
Magnetic Resonance Spectroscopy
Risk factors
Prognosis
topic Chagas Cardiomyopathy
Chagas Disease
Magnetic Resonance Spectroscopy
Risk factors
Prognosis
description Background: Chagas disease (CD) is an important cause of heart failure and mortality, mainly in Latin America. This study evaluated the morphological and functional characteristics of the heart as well the extent of myocardial fibrosis (MF) in patients with CD by cardiac magnetic resonance (CMR). The prognostic value of MF evaluated by myocardialdelayed enhancement (MDE) was compared with that via Rassi score. Methods: This study assessed 39 patients divided into 2 groups: 28 asymptomatic patients as indeterminate form group (IND)
publishDate 2016
dc.date.none.fl_str_mv 2016
2020-07-31T12:47:21Z
2020-07-31T12:47:21Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.5935/abc.20160168
Arquivos Brasileiros De Cardiologia. Rio De Janeiro, v. 107, n. 5, p. 460-466, 2016.
10.5935/abc.20160168
0066-782X
https://repositorio.unifesp.br/handle/11600/56769
WOS:000391430900009
url http://dx.doi.org/10.5935/abc.20160168
https://repositorio.unifesp.br/handle/11600/56769
identifier_str_mv Arquivos Brasileiros De Cardiologia. Rio De Janeiro, v. 107, n. 5, p. 460-466, 2016.
10.5935/abc.20160168
0066-782X
WOS:000391430900009
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos Brasileiros De Cardiologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 460-466
dc.coverage.none.fl_str_mv Rio De Janeiro
dc.publisher.none.fl_str_mv Arquivos Brasileiros Cardiologia
publisher.none.fl_str_mv Arquivos Brasileiros Cardiologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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