Serum Antioxidant Associations with Metabolic Characteristics in Metabolically Healthy and Unhealthy Adolescents with Severe Obesity: An Observational Study

• Autor(a) principal: Stenzel, Ana Paula
• Data de Publicação: 2018
• Outros Autores: Carvalho, Roberta, Jesus, Patricia, Bull, Aline, Pereira, Silvia, Saboya, Carlos [UNIFESP], Ramalho, Andrea
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: https://repositorio.unifesp.br/handle/11600/54170; http://dx.doi.org/10.3390/nu10020150
• topic: obesity; adolescents; Metabolically Healthy Obesity; antioxidants

Considering the inadequacy of some antioxidant nutrients in severely obese adolescents, this study aimed to assess the relationship between antioxidant micronutrients status and metabolic syndrome components in metabolically healthy obesity (MHO) and unhealthy obesity (MUO). We performed an observational study in severely obese adolescents (body mass index > 99th percentile) and they were classified into MHO or MUO, according to the criteria adapted for adolescents. Anthropometric, biochemical, and clinical variables were analyzed to characterize the sample of adolescents. The serum antioxidant nutrients assessed were retinol, beta-carotene, Vitamin E, Vitamin C, zinc and selenium. A total of 60 adolescents aged 17.31 +/- 1.34 years were enrolled. MHO was identified in 23.3% of adolescents. The MHO group showed lower frequency of non-alcoholic fatty liver disease (14.3% vs. 78.3%, p < 0.001) when compared to MUO. A correlation was found between retinol and beta-carotene concentrations with glycemia (r = -0.372