Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both

Detalhes bibliográficos
Autor(a) principal: Medeiros, Wladimir Musetti [UNIFESP]
Data de Publicação: 2018
Outros Autores: Luca, Fabio A. de, Figueredo Junior, Alcides R. de [UNIFESP], Mendes, Felipe A. R., Gun, Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1111/cpf.12420
https://repositorio.unifesp.br/handle/11600/55594
Resumo: Heart rate recovery (HRR) is a strong mortality predictor. Exercise training (ET) and -blocker therapy have significant impact on the HRR of patients following myocardial infarction (MI). However, the combination of ET and -blocker therapy, as well as its effectiveness in patients with a more compromised HRR (12bpm), has been under-studied. Male patients (n=64) post-MI were divided: Training+-blocker (n=19), Training (n=15), -blocker (n=11) and Control (n=19). Participants performed an ergometric test before and after 3months of intervention. HRR was obtained during 5min of recovery and corrected by the cardiac reserve (HRRcorrCR). Compared to pre-intervention, HRRcorrCR was significantly increased during the 1st and 2nd minutes of recovery in the Training+-blocker group (70<bold></bold>5% and 37<bold></bold>5%, respectively
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spelling Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or bothautonomic functionbeta-blockercardiac rehabilitationexercise testingexercise trainingheart diseaseheart rate recoveryHeart rate recovery (HRR) is a strong mortality predictor. Exercise training (ET) and -blocker therapy have significant impact on the HRR of patients following myocardial infarction (MI). However, the combination of ET and -blocker therapy, as well as its effectiveness in patients with a more compromised HRR (12bpm), has been under-studied. Male patients (n=64) post-MI were divided: Training+-blocker (n=19), Training (n=15), -blocker (n=11) and Control (n=19). Participants performed an ergometric test before and after 3months of intervention. HRR was obtained during 5min of recovery and corrected by the cardiac reserve (HRRcorrCR). Compared to pre-intervention, HRRcorrCR was significantly increased during the 1st and 2nd minutes of recovery in the Training+-blocker group (70<bold></bold>5% and 37<bold></bold>5%, respectivelyP<0<bold></bold>05). A significant improvement, lasting from the 1st to the 4th minute of recovery, was also observed in the Training group (47%, 50%, 25% and 8<bold></bold>7%, respectivelyP<0<bold></bold>05). In contrast, the -blocker group showed a reduction in HRRcorrCR during the 2nd and 3rd minutes of recovery (-21<bold></bold>2% and -16<bold></bold>3%, respectivelyP<0<bold></bold>05). In addition, interventions involving ET (Training+b, Training) were significantly more effective in patients with a pre-intervention HRR12bpm than for patients with HRR>12bpm. Combination of -blocker therapy with ET does not compromise the effect of training and instead promotes HRR and aerobic capacity improvement. In addition, this combination is particularly beneficial for individuals presenting with a more compromised HRR. However, chronic administration of -blocker therapy alone did not promote improvement in HRR or aerobic capacity.Santo Amaro Univ UNISA, Lab Exercise Physiol & Cardiac Rehabil GERFE, Dept Med & Physiotherapy, Sao Paulo, BrazilFed Univ Sao Paulo UNIFESP, Pulm Funct & Clin Exercise Physiol Unit SEFICE, Div Resp, Sao Paulo, BrazilIbirapuera Univ UNIB, Dept Rehabil & Funct Capac, Sch Physiotherapy, Sao Paulo, BrazilFed Univ Sao Paulo UNIFESP, Pulm Funct & Clin Exercise Physiol Unit SEFICE, Div Resp, Sao Paulo, BrazilWeb of ScienceWiley2020-07-20T16:30:55Z2020-07-20T16:30:55Z2018info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion351-359http://dx.doi.org/10.1111/cpf.12420Clinical Physiology And Functional Imaging. Hoboken, v. 38, n. 3, p. 351-359, 2018.10.1111/cpf.124201475-0961https://repositorio.unifesp.br/handle/11600/55594WOS:000430103100002engClinical Physiology And Functional ImagingHobokeninfo:eu-repo/semantics/openAccessMedeiros, Wladimir Musetti [UNIFESP]Luca, Fabio A. deFigueredo Junior, Alcides R. de [UNIFESP]Mendes, Felipe A. R.Gun, Carlosreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2021-10-04T21:26:15Zoai:repositorio.unifesp.br/:11600/55594Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652021-10-04T21:26:15Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
title Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
spellingShingle Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
Medeiros, Wladimir Musetti [UNIFESP]
autonomic function
beta-blocker
cardiac rehabilitation
exercise testing
exercise training
heart disease
heart rate recovery
title_short Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
title_full Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
title_fullStr Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
title_full_unstemmed Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
title_sort Heart rate recovery improvement in patients following acute myocardial infarction: exercise training, -blocker therapy or both
author Medeiros, Wladimir Musetti [UNIFESP]
author_facet Medeiros, Wladimir Musetti [UNIFESP]
Luca, Fabio A. de
Figueredo Junior, Alcides R. de [UNIFESP]
Mendes, Felipe A. R.
Gun, Carlos
author_role author
author2 Luca, Fabio A. de
Figueredo Junior, Alcides R. de [UNIFESP]
Mendes, Felipe A. R.
Gun, Carlos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Medeiros, Wladimir Musetti [UNIFESP]
Luca, Fabio A. de
Figueredo Junior, Alcides R. de [UNIFESP]
Mendes, Felipe A. R.
Gun, Carlos
dc.subject.por.fl_str_mv autonomic function
beta-blocker
cardiac rehabilitation
exercise testing
exercise training
heart disease
heart rate recovery
topic autonomic function
beta-blocker
cardiac rehabilitation
exercise testing
exercise training
heart disease
heart rate recovery
description Heart rate recovery (HRR) is a strong mortality predictor. Exercise training (ET) and -blocker therapy have significant impact on the HRR of patients following myocardial infarction (MI). However, the combination of ET and -blocker therapy, as well as its effectiveness in patients with a more compromised HRR (12bpm), has been under-studied. Male patients (n=64) post-MI were divided: Training+-blocker (n=19), Training (n=15), -blocker (n=11) and Control (n=19). Participants performed an ergometric test before and after 3months of intervention. HRR was obtained during 5min of recovery and corrected by the cardiac reserve (HRRcorrCR). Compared to pre-intervention, HRRcorrCR was significantly increased during the 1st and 2nd minutes of recovery in the Training+-blocker group (70<bold></bold>5% and 37<bold></bold>5%, respectively
publishDate 2018
dc.date.none.fl_str_mv 2018
2020-07-20T16:30:55Z
2020-07-20T16:30:55Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/cpf.12420
Clinical Physiology And Functional Imaging. Hoboken, v. 38, n. 3, p. 351-359, 2018.
10.1111/cpf.12420
1475-0961
https://repositorio.unifesp.br/handle/11600/55594
WOS:000430103100002
url http://dx.doi.org/10.1111/cpf.12420
https://repositorio.unifesp.br/handle/11600/55594
identifier_str_mv Clinical Physiology And Functional Imaging. Hoboken, v. 38, n. 3, p. 351-359, 2018.
10.1111/cpf.12420
1475-0961
WOS:000430103100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clinical Physiology And Functional Imaging
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 351-359
dc.coverage.none.fl_str_mv Hoboken
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268351984173056

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