A new equationto predict peak VO2 in obese patients during cardiopulmonary exercise testing

• Autor(a) principal: Barbosa, Alan Carlos Brisola [UNIFESP]
• Data de Publicação: 2018
• Outros Autores: Sperandio, Evandro Fornias [UNIFESP], Gonze, Bárbara de Barros [UNIFESP], Spina, Giovanna Domingues [UNIFESP], Arantes, Rodolfo Leite, Gagliardi, Antonio Ricardo de Toledo, Romiti, Marcello, Dourado, Victor Zuniga [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: https://dx.doi.org/10.1111/cpf.12438; https://repositorio.unifesp.br/handle/11600/55595
• topic: Obesity; Oxygen consumption; Physical exertion; Physical fitness; Stress test

We aimed to develop an equationto predict peak VO2 in obese subjects undergoing CPET. In addition, we evaluated and compared three published equations. We randomized 346 obese subjects undergoing CPET into a group for developing the equation(n=272) and a group for cross-validation (n=74), compared through the Bland and Altman method. Height, sex and age were responsible for 85<bold></bold>5% of total variability of the peak VO2. Additional 1% and 0<bold></bold>7% of the variability were, respectively, explained by physical inactivity and diabetes. The equation devised was as follows: The mean difference between the estimated and measured peak VO2 was 7mlmin(-1), with a 23<bold></bold>9% bias. Published equations overestimated the peak VO2 by 35<bold></bold>3%, 49<bold></bold>1% and 46<bold></bold>2% bias. The equationdeveloped in this study performed better in predicting peak VO2 in obese adults improving ramp protocol design and CRF evaluations in obese subjects.