Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://dx.doi.org/10.1038/ncomms15955 https://repositorio.unifesp.br/handle/11600/53458 |
Resumo: | Marine viruses are key drivers of host diversity, population dynamics and biogeochemical cycling and contribute to the daily flux of billions of tons of organic matter. Despite recent advancements in metagenomics, much of their biodiversity remains uncharacterized. Here we report a data set of 27,346 marine virome contigs that includes 44 complete genomes. These outnumber all currently known phage genomes in marine habitats and include members of previously uncharacterized lineages. We designed a new method for host prediction based on co-occurrence associations that reveals these viruses infect dominant members of the marine microbiome such as Prochlorococcus and Pelagibacter. A negative association between host abundance and the virus-to-host ratio supports the recently proposed Piggyback-the-Winner model of reduced phage lysis at higher host densities. An analysis of the abundance patterns of viruses throughout the oceans revealed how marine viral communities adapt to various seasonal, temperature and photic regimes according to targeted hosts and the diversity of auxiliary metabolic genes. |
id |
UFSP_d943c6eb9f249bf4af39c5d1db802d04 |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br:11600/53458 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Coutinho, Felipe H.Silveira, Cynthia B.Gregoracci, Gustavo Bueno [UNIFESP]Thompson, Cristiane C.Edwards, Robert A.Brussaard, Corina P. D.Dutilh, Bas E.Thompson, Fabiano Lopes2020-06-26T16:30:17Z2020-06-26T16:30:17Z2017https://dx.doi.org/10.1038/ncomms15955Nature Communications. London, v. 8, p. -, 2017.2041-1723https://repositorio.unifesp.br/handle/11600/53458WOS000404780000001.pdf10.1038/ncomms15955WOS:000404780000001Marine viruses are key drivers of host diversity, population dynamics and biogeochemical cycling and contribute to the daily flux of billions of tons of organic matter. Despite recent advancements in metagenomics, much of their biodiversity remains uncharacterized. Here we report a data set of 27,346 marine virome contigs that includes 44 complete genomes. These outnumber all currently known phage genomes in marine habitats and include members of previously uncharacterized lineages. We designed a new method for host prediction based on co-occurrence associations that reveals these viruses infect dominant members of the marine microbiome such as Prochlorococcus and Pelagibacter. A negative association between host abundance and the virus-to-host ratio supports the recently proposed Piggyback-the-Winner model of reduced phage lysis at higher host densities. An analysis of the abundance patterns of viruses throughout the oceans revealed how marine viral communities adapt to various seasonal, temperature and photic regimes according to targeted hosts and the diversity of auxiliary metabolic genes.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)Ciencia sem fronteiras programUniv Fed Rio de Janeiro, IB, BR-21944970 Rio de Janeiro, BrazilRadboud Univ Nijmegen, Radboud Inst Mol Life Sci, CMBI, Med Ctr, NL-6500 HB Nijmegen, NetherlandsUniv Utrecht, Theoret Biol & Bioinformat, NL-3584 CH Utrecht, NetherlandsSan Diego State Univ, Dept Biol, San Diego, CA 92182 USAUniv Fed Sao Paulo UNIFESP, Dept Ciencias Mar, BR-11070100 Baixada Santista, BrazilNIOZ Royal Netherlands Inst Sea Res, Dept Marine Microbiol & Biogeochem, POB 59, NL-1790 AB Den Burg, NetherlandsUniv Utrecht, POB 59, NL-1790 AB Den Burg, NetherlandsUniv Amsterdam, Dept Aquat Microbiol, IBED, NL-1090 GE Amsterdam, NetherlandsUniv Fed Rio de Janeiro, COPPE, SAGE, BR-21941950 Rio de Janeiro, BrazilUniv Fed Sao Paulo UNIFESP, Dept Ciencias Mar, BR-11070100 Baixada Santista, BrazilCiencia sem fronteiras program: 864.14.004Web of Science-engNature Publishing GroupNature CommunicationsMarine viruses discovered via metagenomics shed light on viral strategies throughout the oceansinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleLondon8info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000404780000001.pdfapplication/pdf1851092${dspace.ui.url}/bitstream/11600/53458/1/WOS000404780000001.pdfec84a354726c389f0c59f25a8d7b824dMD51open accessTEXTWOS000404780000001.pdf.txtWOS000404780000001.pdf.txtExtracted texttext/plain71128${dspace.ui.url}/bitstream/11600/53458/5/WOS000404780000001.pdf.txt9a4f7d055d0987880d053b90efe534a0MD55open accessTHUMBNAILWOS000404780000001.pdf.jpgWOS000404780000001.pdf.jpgIM Thumbnailimage/jpeg6416${dspace.ui.url}/bitstream/11600/53458/7/WOS000404780000001.pdf.jpg5cf9c7c2ec87d9f230f9edec53aca9f9MD57open access11600/534582023-06-05 19:39:05.302open accessoai:repositorio.unifesp.br:11600/53458Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:39:05Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
title |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
spellingShingle |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans Coutinho, Felipe H. |
title_short |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
title_full |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
title_fullStr |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
title_full_unstemmed |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
title_sort |
Marine viruses discovered via metagenomics shed light on viral strategies throughout the oceans |
author |
Coutinho, Felipe H. |
author_facet |
Coutinho, Felipe H. Silveira, Cynthia B. Gregoracci, Gustavo Bueno [UNIFESP] Thompson, Cristiane C. Edwards, Robert A. Brussaard, Corina P. D. Dutilh, Bas E. Thompson, Fabiano Lopes |
author_role |
author |
author2 |
Silveira, Cynthia B. Gregoracci, Gustavo Bueno [UNIFESP] Thompson, Cristiane C. Edwards, Robert A. Brussaard, Corina P. D. Dutilh, Bas E. Thompson, Fabiano Lopes |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Coutinho, Felipe H. Silveira, Cynthia B. Gregoracci, Gustavo Bueno [UNIFESP] Thompson, Cristiane C. Edwards, Robert A. Brussaard, Corina P. D. Dutilh, Bas E. Thompson, Fabiano Lopes |
description |
Marine viruses are key drivers of host diversity, population dynamics and biogeochemical cycling and contribute to the daily flux of billions of tons of organic matter. Despite recent advancements in metagenomics, much of their biodiversity remains uncharacterized. Here we report a data set of 27,346 marine virome contigs that includes 44 complete genomes. These outnumber all currently known phage genomes in marine habitats and include members of previously uncharacterized lineages. We designed a new method for host prediction based on co-occurrence associations that reveals these viruses infect dominant members of the marine microbiome such as Prochlorococcus and Pelagibacter. A negative association between host abundance and the virus-to-host ratio supports the recently proposed Piggyback-the-Winner model of reduced phage lysis at higher host densities. An analysis of the abundance patterns of viruses throughout the oceans revealed how marine viral communities adapt to various seasonal, temperature and photic regimes according to targeted hosts and the diversity of auxiliary metabolic genes. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2020-06-26T16:30:17Z |
dc.date.available.fl_str_mv |
2020-06-26T16:30:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.].fl_str_mv |
https://dx.doi.org/10.1038/ncomms15955 |
dc.identifier.citation.fl_str_mv |
Nature Communications. London, v. 8, p. -, 2017. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/53458 |
dc.identifier.issn.none.fl_str_mv |
2041-1723 |
dc.identifier.file.none.fl_str_mv |
WOS000404780000001.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1038/ncomms15955 |
dc.identifier.wos.none.fl_str_mv |
WOS:000404780000001 |
url |
https://dx.doi.org/10.1038/ncomms15955 https://repositorio.unifesp.br/handle/11600/53458 |
identifier_str_mv |
Nature Communications. London, v. 8, p. -, 2017. 2041-1723 WOS000404780000001.pdf 10.1038/ncomms15955 WOS:000404780000001 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Nature Communications |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
- |
dc.coverage.none.fl_str_mv |
London |
dc.publisher.none.fl_str_mv |
Nature Publishing Group |
publisher.none.fl_str_mv |
Nature Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
bitstream.url.fl_str_mv |
${dspace.ui.url}/bitstream/11600/53458/1/WOS000404780000001.pdf ${dspace.ui.url}/bitstream/11600/53458/5/WOS000404780000001.pdf.txt ${dspace.ui.url}/bitstream/11600/53458/7/WOS000404780000001.pdf.jpg |
bitstream.checksum.fl_str_mv |
ec84a354726c389f0c59f25a8d7b824d 9a4f7d055d0987880d053b90efe534a0 5cf9c7c2ec87d9f230f9edec53aca9f9 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1783460304671211520 |