O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans

Detalhes bibliográficos
Autor(a) principal: Reis-Filho, João Baptista dos [UNIFESP]
Data de Publicação: 1985
Outros Autores: Neves, Afonso Carlos [UNIFESP], Zymberg, Samuel Tau [UNIFESP], Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0036-46651985000400003
http://repositorio.unifesp.br/handle/11600/203
Resumo: The Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites.
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spelling O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformansThe CSF in cryptococcal meningitisThe Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites.A criptococose, conhecida desde 1905, é doença grave, causada pelo Cryptococcus neoformans. Nesta entidade o estudo do líquido cefalorraquiano é muito importante visto que o sistema nervoso está envolvido em 81% dos casos5. O propósito do presente trabalho é o de evidenciar as alterações do líquido cefalorraquiano inicial nas meningencefalites criptocócicas e demonstrar a importância de exame minucioso do líquido cefalorraquiano para o diagnóstico precoce desta doença. O material é constituído por 46 observações de pacientes com diagnóstico de meningencefalite criptocócica. O quadro inflamatório crônico, caracterizado por pleocitose predominantemente linfocitária, hiperproteinorraquia e glicose diminuída foi observado em 54% das amostras de líquido cefalorraquiano. Em 69% dos casos o líquido cefalorraquiano mostrava hipertensão. A glicose estava diminuída em 61% dos pacientes e a taxa de cloretos em 16%. Eosinófilos em baixa percentagem foram observados em 48% dos casos. O criptococo foi identificado no líquido cefalorraquiano de 98% dos pacientes; é salientada a importância da pesquisa a fresco do fungo pelo método da tinta da China, sempre que uma amostra de líquido cefalorraquiano revelar pleocitose. Esta é uma conduta básica para o diagnóstico precoce da criptococose do sistema nervoso.Escola Paulista de Medicina Setor de LCREscola Paulista de MedicinaUNIFESP, EPM, Setor de LCREscola Paulista de MedicinaSciELOInstituto de Medicina TropicalUniversidade Federal de São Paulo (UNIFESP)Reis-Filho, João Baptista dos [UNIFESP]Neves, Afonso Carlos [UNIFESP]Zymberg, Samuel Tau [UNIFESP]Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]2015-06-14T13:24:16Z2015-06-14T13:24:16Z1985-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion173-178application/pdfhttp://dx.doi.org/10.1590/S0036-46651985000400003REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 198510.1590/S0036-46651985000400003S0036-46651985000400003.pdf0036-4665S0036-46651985000400003http://repositorio.unifesp.br/handle/11600/203WOS:A1985ARE8900003porRevista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T06:33:25Zoai:repositorio.unifesp.br/:11600/203Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T06:33:25Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
The CSF in cryptococcal meningitis
title O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
spellingShingle O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
Reis-Filho, João Baptista dos [UNIFESP]
title_short O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
title_full O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
title_fullStr O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
title_full_unstemmed O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
title_sort O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
author Reis-Filho, João Baptista dos [UNIFESP]
author_facet Reis-Filho, João Baptista dos [UNIFESP]
Neves, Afonso Carlos [UNIFESP]
Zymberg, Samuel Tau [UNIFESP]
Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]
author_role author
author2 Neves, Afonso Carlos [UNIFESP]
Zymberg, Samuel Tau [UNIFESP]
Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Reis-Filho, João Baptista dos [UNIFESP]
Neves, Afonso Carlos [UNIFESP]
Zymberg, Samuel Tau [UNIFESP]
Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]
description The Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites.
publishDate 1985
dc.date.none.fl_str_mv 1985-08-01
2015-06-14T13:24:16Z
2015-06-14T13:24:16Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0036-46651985000400003
REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 1985
10.1590/S0036-46651985000400003
S0036-46651985000400003.pdf
0036-4665
S0036-46651985000400003
http://repositorio.unifesp.br/handle/11600/203
WOS:A1985ARE8900003
url http://dx.doi.org/10.1590/S0036-46651985000400003
http://repositorio.unifesp.br/handle/11600/203
identifier_str_mv REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 1985
10.1590/S0036-46651985000400003
S0036-46651985000400003.pdf
0036-4665
S0036-46651985000400003
WOS:A1985ARE8900003
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 173-178
application/pdf
dc.publisher.none.fl_str_mv Instituto de Medicina Tropical
publisher.none.fl_str_mv Instituto de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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