O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans
Autor(a) principal: | |
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Data de Publicação: | 1985 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0036-46651985000400003 http://repositorio.unifesp.br/handle/11600/203 |
Resumo: | The Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites. |
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O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformansThe CSF in cryptococcal meningitisThe Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites.A criptococose, conhecida desde 1905, é doença grave, causada pelo Cryptococcus neoformans. Nesta entidade o estudo do líquido cefalorraquiano é muito importante visto que o sistema nervoso está envolvido em 81% dos casos5. O propósito do presente trabalho é o de evidenciar as alterações do líquido cefalorraquiano inicial nas meningencefalites criptocócicas e demonstrar a importância de exame minucioso do líquido cefalorraquiano para o diagnóstico precoce desta doença. O material é constituído por 46 observações de pacientes com diagnóstico de meningencefalite criptocócica. O quadro inflamatório crônico, caracterizado por pleocitose predominantemente linfocitária, hiperproteinorraquia e glicose diminuída foi observado em 54% das amostras de líquido cefalorraquiano. Em 69% dos casos o líquido cefalorraquiano mostrava hipertensão. A glicose estava diminuída em 61% dos pacientes e a taxa de cloretos em 16%. Eosinófilos em baixa percentagem foram observados em 48% dos casos. O criptococo foi identificado no líquido cefalorraquiano de 98% dos pacientes; é salientada a importância da pesquisa a fresco do fungo pelo método da tinta da China, sempre que uma amostra de líquido cefalorraquiano revelar pleocitose. Esta é uma conduta básica para o diagnóstico precoce da criptococose do sistema nervoso.Escola Paulista de Medicina Setor de LCREscola Paulista de MedicinaUNIFESP, EPM, Setor de LCREscola Paulista de MedicinaSciELOInstituto de Medicina TropicalUniversidade Federal de São Paulo (UNIFESP)Reis-Filho, João Baptista dos [UNIFESP]Neves, Afonso Carlos [UNIFESP]Zymberg, Samuel Tau [UNIFESP]Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP]2015-06-14T13:24:16Z2015-06-14T13:24:16Z1985-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion173-178application/pdfhttp://dx.doi.org/10.1590/S0036-46651985000400003REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 198510.1590/S0036-46651985000400003S0036-46651985000400003.pdf0036-4665S0036-46651985000400003http://repositorio.unifesp.br/handle/11600/203WOS:A1985ARE8900003porRevista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T06:33:25Zoai:repositorio.unifesp.br/:11600/203Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T06:33:25Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans The CSF in cryptococcal meningitis |
title |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
spellingShingle |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans Reis-Filho, João Baptista dos [UNIFESP] |
title_short |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
title_full |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
title_fullStr |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
title_full_unstemmed |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
title_sort |
O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans |
author |
Reis-Filho, João Baptista dos [UNIFESP] |
author_facet |
Reis-Filho, João Baptista dos [UNIFESP] Neves, Afonso Carlos [UNIFESP] Zymberg, Samuel Tau [UNIFESP] Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP] |
author_role |
author |
author2 |
Neves, Afonso Carlos [UNIFESP] Zymberg, Samuel Tau [UNIFESP] Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Reis-Filho, João Baptista dos [UNIFESP] Neves, Afonso Carlos [UNIFESP] Zymberg, Samuel Tau [UNIFESP] Oliveira, Roberto de Magalhaes Carneiro de [UNIFESP] |
description |
The Authors emphasize the importance of cerebrospinal fluid (CSF) in the diagnoses of nervous system cryptococcosis. It is analysed 46 observations of patients with criptococcal meningitis searched in the 1953 1984 period, 32 male and 14 female. The age ranged between 11 and 59 years. The cell count of CSF was high as 1050 and as low as 9 per cubic millimeter. The cells were mainly of the mononuclear type. The protein content was normal in 14% of the cases and increased in 86%. The sugar levels were normal or with a discreet elevation in 39% and low in 61%. In 45 cases was perform- ed the India Ink test in the CSF sediment and the Cryptococcus neoformans was found in 44. In this one with India Ink test negative the culture in Sabouraud medium allowed the growth of yeast organism. It is very important to perform the India Ink test in every CSF sample with pleocitosis, in order to make early diagnosis. In this paper the spinal fluid change looks like that of tuberculous meningitis in 54% of the patients. In 7 samples the cloudness of the CSF was given only by the high number of parasites. |
publishDate |
1985 |
dc.date.none.fl_str_mv |
1985-08-01 2015-06-14T13:24:16Z 2015-06-14T13:24:16Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0036-46651985000400003 REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 1985 10.1590/S0036-46651985000400003 S0036-46651985000400003.pdf 0036-4665 S0036-46651985000400003 http://repositorio.unifesp.br/handle/11600/203 WOS:A1985ARE8900003 |
url |
http://dx.doi.org/10.1590/S0036-46651985000400003 http://repositorio.unifesp.br/handle/11600/203 |
identifier_str_mv |
REIS-FILHO, João Baptista dos et al . O líquido cefalorraquiano inicial nas meningencefalites por Cryptococcus neoformans. Rev. Inst. Med. trop. S. Paulo, São Paulo , v. 27, n. 4, p. 173-178, ago. 1985 10.1590/S0036-46651985000400003 S0036-46651985000400003.pdf 0036-4665 S0036-46651985000400003 WOS:A1985ARE8900003 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista do Instituto de Medicina Tropical de São Paulo |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
173-178 application/pdf |
dc.publisher.none.fl_str_mv |
Instituto de Medicina Tropical |
publisher.none.fl_str_mv |
Instituto de Medicina Tropical |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
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Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268312634261504 |