Fibrinogênio como fator de risco independente de doença vascular cerebral

• Autor(a) principal: Fukujima, Marcia Maiumi [UNIFESP]
• Data de Publicação: 1997
• Outros Autores: Martinez, Tânia Leme da Rocha [UNIFESP], Pinto, Leonor do Espírito Santo de Almeida [UNIFESP], Auriemo, Caio R.c. [UNIFESP], Andrade, Luiz Augusto Franco de [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-282X1997000500009; http://repositorio.unifesp.br/handle/11600/457
• topic: stroke; cerebrovascular disease; fibrinogen; risk factor; carotid ultrasonography; doença cerebrovascular; fibrinogênio; fator de risco; ultra-sonografia carotídea

We have studied fibrinogen levels (Clauss technique) in atherothrombotic ischemic stroke patients, in order to determine its role as a thombogenic risk factor. Twenty nine patients (20 men and 9 women) between 25 and 79 years old were studied; they all have had a atherothrombotic stroke. They were classified into two groups according to the result of their carotid doppler ultrasonography: g1 - without carotid flow reduction (n=l 9) and g2 - with carotid flow reduction (n=10). The fibrinogen mean value was 269mg/dl in gl and 353 mg/dl in g2. There were 47% of patients in gl and 80% of patients in g2 who presented levels >300 mg/dl. The proportions of the groups were significantly different (p<0,05). Considering the epidemiological value of 300 mg/dl, we conclude that the fibrinogen can be an independent risk factor for ischemic atherothrombotic stroke, specially in those whose carotid flow is reduced.