Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita

Detalhes bibliográficos
Autor(a) principal: Penido, Norma de Oliveira [UNIFESP]
Data de Publicação: 2005
Outros Autores: Ramos, Hugo Valter Lisboa [UNIFESP], Barros, Flávia Alencar [UNIFESP], Cruz, Oswaldo Laércio Mendonça [UNIFESP], Toledo, Ronaldo Nunes [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0034-72992005000500014
http://repositorio.unifesp.br/handle/11600/2726
Resumo: Out of the many forms of therapy for sudden deafness, some require hospitalization and present significant risks. AIM: This prospective study analyzes etiology and evolution in cases of sudden deafness (SD) where outpatient oral treatment was used. STUDY DESIGN: clinical with transversal cohort. MATERIAL AND METHOD: Forty cases of sudden hearing loss were followed for at least one year. All were submitted to initial clinical evaluation, auditory tests, routine blood analysis, and magnetic resonance imaging. All received initial treatment with pentoxifylline and prednisone. RESULTS: 45% (n=18) presented normal auditory thresholds, 40% (n=16) showed some improvement in hearing, 15% (n=6) maintained initial hearing level. Nine cases (22.5%) presented clinical conditions possibly implicated in hearing loss (viral infection, immunomediated hearing loss, vascular disorders, and so on); three (7.5%) had cerebellopontine tumors. Evolution of hearing in these 12 cases with presumed etiology presented no differences from hearing in the 28 cases without any known etiological factor. Clinical treatment within the first seven days was the only statistically significantly different condition in patients who improved hearing. CONCLUSIONS: An objective search for etiological bases should be conducted in any case of acute sensorineural hearing loss. The presence of cerebellopontine tumors in 7.5% of cases of SD, among other treated causes, justifies a thorough clinical investigation in these patients. Overall good evolution of hearing was observed in 67.5% of cases of SD, regardless of its etiology. Therapy within the first seven days of SD was significantly related to better outcomes in hearing.
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spelling Fatores clínicos, etiológicos e evolutivos da audição na surdez súbitaClinical, etiological and progression factors of hearing in sudden deafnesssudden Deafnesssensorineural hearing losssurdez súbitadisacusia neurossensorialOut of the many forms of therapy for sudden deafness, some require hospitalization and present significant risks. AIM: This prospective study analyzes etiology and evolution in cases of sudden deafness (SD) where outpatient oral treatment was used. STUDY DESIGN: clinical with transversal cohort. MATERIAL AND METHOD: Forty cases of sudden hearing loss were followed for at least one year. All were submitted to initial clinical evaluation, auditory tests, routine blood analysis, and magnetic resonance imaging. All received initial treatment with pentoxifylline and prednisone. RESULTS: 45% (n=18) presented normal auditory thresholds, 40% (n=16) showed some improvement in hearing, 15% (n=6) maintained initial hearing level. Nine cases (22.5%) presented clinical conditions possibly implicated in hearing loss (viral infection, immunomediated hearing loss, vascular disorders, and so on); three (7.5%) had cerebellopontine tumors. Evolution of hearing in these 12 cases with presumed etiology presented no differences from hearing in the 28 cases without any known etiological factor. Clinical treatment within the first seven days was the only statistically significantly different condition in patients who improved hearing. CONCLUSIONS: An objective search for etiological bases should be conducted in any case of acute sensorineural hearing loss. The presence of cerebellopontine tumors in 7.5% of cases of SD, among other treated causes, justifies a thorough clinical investigation in these patients. Overall good evolution of hearing was observed in 67.5% of cases of SD, regardless of its etiology. Therapy within the first seven days of SD was significantly related to better outcomes in hearing.Existem várias terapias preconizadas para o tratamento da surdez súbita, algumas apresentam riscos significativos necessitando inclusive de internação hospitalar. OBJETIVO: Este estudo prospectivo analisa aspectos clínicos, etiológicos e evolutivos nos casos de surdez súbita (SS) em pacientes tratados ambulatorialmente com medicação oral. FORMA DE ESTUDO: clínico com coorte transversal. MATERIAL E MÉTODO: 40 pacientes com perda súbita da audição submeteram inicialmente a avaliação clínica otorrinolaringológica, testes audiométricos, análise hematológica e ressonância magnética. Confirmado o diagnóstico de SS, todos os pacientes receberam inicialmente prednisona e pentoxifilina sendo acompanhados por pelo menos um ano. RESULTADO: 45% (n=18) apresentaram normalização dos limiares auditivos, 40% (n=16) apresentaram melhoras auditivas, 15% (n=6) mantiveram os mesmos limiares iniciais. Nove casos (22,5%) apresentaram manifestações clínicas que justificaram a perda auditiva (infecção viral, fatores imunomediados, alterações vasculares e outros), três (7,5%) apresentaram tumores na região do ângulo ponto-cerebelar. A evolução auditiva nestes 12 casos com etiologia presumida não apresentou diferença estatística significante em relação aos 28 casos sem etiologia definida. O tratamento clínico instituído nos primeiros sete dias de instalação da perda auditiva, nos pacientes que obtiveram melhora, foi o único parâmetro estatisticamente significante dos fatores prognóstico avaliado. CONCLUSÃO: A pesquisa exaustiva etiológica deve ser realizada em qualquer caso de perda auditiva neurossensorial aguda. A presença de 7,5% de tumores localizados na região do ângulo ponto-cerebelar nos casos de SS juntamente com outras causas tratáveis justifica a investigação clínica nestes pacientes. Nossos pacientes apresentaram uma boa melhora auditiva em 67,5% dos casos, independentemente da etiologia. O início da terapia nos primeiros sete dias de instalação da perda auditiva foi o único fator de melhora significante dos limiares auditivos.UNIFESP-EpmUNIFESP-EpmSciELOABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-FacialUniversidade Federal de São Paulo (UNIFESP)Penido, Norma de Oliveira [UNIFESP]Ramos, Hugo Valter Lisboa [UNIFESP]Barros, Flávia Alencar [UNIFESP]Cruz, Oswaldo Laércio Mendonça [UNIFESP]Toledo, Ronaldo Nunes [UNIFESP]2015-06-14T13:31:46Z2015-06-14T13:31:46Z2005-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion633-638application/pdfhttp://dx.doi.org/10.1590/S0034-72992005000500014Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 71, n. 5, p. 633-638, 2005.10.1590/S0034-72992005000500014S0034-72992005000500014.pdf0034-7299S0034-72992005000500014http://repositorio.unifesp.br/handle/11600/2726porRevista Brasileira de Otorrinolaringologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T13:50:04Zoai:repositorio.unifesp.br/:11600/2726Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T13:50:04Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
Clinical, etiological and progression factors of hearing in sudden deafness
title Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
spellingShingle Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
Penido, Norma de Oliveira [UNIFESP]
sudden Deafness
sensorineural hearing loss
surdez súbita
disacusia neurossensorial
title_short Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
title_full Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
title_fullStr Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
title_full_unstemmed Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
title_sort Fatores clínicos, etiológicos e evolutivos da audição na surdez súbita
author Penido, Norma de Oliveira [UNIFESP]
author_facet Penido, Norma de Oliveira [UNIFESP]
Ramos, Hugo Valter Lisboa [UNIFESP]
Barros, Flávia Alencar [UNIFESP]
Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Toledo, Ronaldo Nunes [UNIFESP]
author_role author
author2 Ramos, Hugo Valter Lisboa [UNIFESP]
Barros, Flávia Alencar [UNIFESP]
Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Toledo, Ronaldo Nunes [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Penido, Norma de Oliveira [UNIFESP]
Ramos, Hugo Valter Lisboa [UNIFESP]
Barros, Flávia Alencar [UNIFESP]
Cruz, Oswaldo Laércio Mendonça [UNIFESP]
Toledo, Ronaldo Nunes [UNIFESP]
dc.subject.por.fl_str_mv sudden Deafness
sensorineural hearing loss
surdez súbita
disacusia neurossensorial
topic sudden Deafness
sensorineural hearing loss
surdez súbita
disacusia neurossensorial
description Out of the many forms of therapy for sudden deafness, some require hospitalization and present significant risks. AIM: This prospective study analyzes etiology and evolution in cases of sudden deafness (SD) where outpatient oral treatment was used. STUDY DESIGN: clinical with transversal cohort. MATERIAL AND METHOD: Forty cases of sudden hearing loss were followed for at least one year. All were submitted to initial clinical evaluation, auditory tests, routine blood analysis, and magnetic resonance imaging. All received initial treatment with pentoxifylline and prednisone. RESULTS: 45% (n=18) presented normal auditory thresholds, 40% (n=16) showed some improvement in hearing, 15% (n=6) maintained initial hearing level. Nine cases (22.5%) presented clinical conditions possibly implicated in hearing loss (viral infection, immunomediated hearing loss, vascular disorders, and so on); three (7.5%) had cerebellopontine tumors. Evolution of hearing in these 12 cases with presumed etiology presented no differences from hearing in the 28 cases without any known etiological factor. Clinical treatment within the first seven days was the only statistically significantly different condition in patients who improved hearing. CONCLUSIONS: An objective search for etiological bases should be conducted in any case of acute sensorineural hearing loss. The presence of cerebellopontine tumors in 7.5% of cases of SD, among other treated causes, justifies a thorough clinical investigation in these patients. Overall good evolution of hearing was observed in 67.5% of cases of SD, regardless of its etiology. Therapy within the first seven days of SD was significantly related to better outcomes in hearing.
publishDate 2005
dc.date.none.fl_str_mv 2005-10-01
2015-06-14T13:31:46Z
2015-06-14T13:31:46Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0034-72992005000500014
Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 71, n. 5, p. 633-638, 2005.
10.1590/S0034-72992005000500014
S0034-72992005000500014.pdf
0034-7299
S0034-72992005000500014
http://repositorio.unifesp.br/handle/11600/2726
url http://dx.doi.org/10.1590/S0034-72992005000500014
http://repositorio.unifesp.br/handle/11600/2726
identifier_str_mv Revista Brasileira de Otorrinolaringologia. ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial, v. 71, n. 5, p. 633-638, 2005.
10.1590/S0034-72992005000500014
S0034-72992005000500014.pdf
0034-7299
S0034-72992005000500014
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira de Otorrinolaringologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 633-638
application/pdf
dc.publisher.none.fl_str_mv ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
publisher.none.fl_str_mv ABORL-CCF Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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