Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://dx.doi.org/10.1590/S0100-879X2006000800017 https://repositorio.unifesp.br/handle/11600/3188 |
Resumo: | The physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment. |
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Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomySleep apnea syndromeObesitySurgeryTonsillectomyApnea and hypopnea indexThe physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment.Universidade Federal de São Paulo (UNIFESP) Departamento de OtorrinolaringologiaUniversidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia Instituto do SonoUNIFESP, Depto. de OtorrinolaringologiaUNIFESP, Depto. de Psicobiologia Instituto do SonoSciELOAssociação Brasileira de Divulgação CientíficaUniversidade Federal de São Paulo (UNIFESP)Martinho, Fernanda Louise [UNIFESP]Zonato, Adriane Iurck [UNIFESP]Bittencourt, Lia Rita Azeredo [UNIFESP]Soares, Maria Claudia Mattos [UNIFESP]Silva, Rogério Fernandes Nunes da [UNIFESP]Gregório, Luiz Carlos [UNIFESP]Tufik, Sergio [UNIFESP]2015-06-14T13:36:22Z2015-06-14T13:36:22Z2006-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1137-1142application/pdfhttps://dx.doi.org/10.1590/S0100-879X2006000800017Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006.10.1590/S0100-879X2006000800017S0100-879X2006000800017.pdf0100-879XS0100-879X2006000800017https://repositorio.unifesp.br/handle/11600/3188WOS:000239936900017engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T17:57:39Zoai:repositorio.unifesp.br/:11600/3188Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T17:57:39Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
title |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
spellingShingle |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy Martinho, Fernanda Louise [UNIFESP] Sleep apnea syndrome Obesity Surgery Tonsillectomy Apnea and hypopnea index |
title_short |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
title_full |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
title_fullStr |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
title_full_unstemmed |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
title_sort |
Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy |
author |
Martinho, Fernanda Louise [UNIFESP] |
author_facet |
Martinho, Fernanda Louise [UNIFESP] Zonato, Adriane Iurck [UNIFESP] Bittencourt, Lia Rita Azeredo [UNIFESP] Soares, Maria Claudia Mattos [UNIFESP] Silva, Rogério Fernandes Nunes da [UNIFESP] Gregório, Luiz Carlos [UNIFESP] Tufik, Sergio [UNIFESP] |
author_role |
author |
author2 |
Zonato, Adriane Iurck [UNIFESP] Bittencourt, Lia Rita Azeredo [UNIFESP] Soares, Maria Claudia Mattos [UNIFESP] Silva, Rogério Fernandes Nunes da [UNIFESP] Gregório, Luiz Carlos [UNIFESP] Tufik, Sergio [UNIFESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Martinho, Fernanda Louise [UNIFESP] Zonato, Adriane Iurck [UNIFESP] Bittencourt, Lia Rita Azeredo [UNIFESP] Soares, Maria Claudia Mattos [UNIFESP] Silva, Rogério Fernandes Nunes da [UNIFESP] Gregório, Luiz Carlos [UNIFESP] Tufik, Sergio [UNIFESP] |
dc.subject.por.fl_str_mv |
Sleep apnea syndrome Obesity Surgery Tonsillectomy Apnea and hypopnea index |
topic |
Sleep apnea syndrome Obesity Surgery Tonsillectomy Apnea and hypopnea index |
description |
The physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-08-01 2015-06-14T13:36:22Z 2015-06-14T13:36:22Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://dx.doi.org/10.1590/S0100-879X2006000800017 Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006. 10.1590/S0100-879X2006000800017 S0100-879X2006000800017.pdf 0100-879X S0100-879X2006000800017 https://repositorio.unifesp.br/handle/11600/3188 WOS:000239936900017 |
url |
https://dx.doi.org/10.1590/S0100-879X2006000800017 https://repositorio.unifesp.br/handle/11600/3188 |
identifier_str_mv |
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006. 10.1590/S0100-879X2006000800017 S0100-879X2006000800017.pdf 0100-879X S0100-879X2006000800017 WOS:000239936900017 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1137-1142 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268463798026240 |