Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy

Detalhes bibliográficos
Autor(a) principal: Martinho, Fernanda Louise [UNIFESP]
Data de Publicação: 2006
Outros Autores: Zonato, Adriane Iurck [UNIFESP], Bittencourt, Lia Rita Azeredo [UNIFESP], Soares, Maria Claudia Mattos [UNIFESP], Silva, Rogério Fernandes Nunes da [UNIFESP], Gregório, Luiz Carlos [UNIFESP], Tufik, Sergio [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://dx.doi.org/10.1590/S0100-879X2006000800017
https://repositorio.unifesp.br/handle/11600/3188
Resumo: The physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment.
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spelling Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomySleep apnea syndromeObesitySurgeryTonsillectomyApnea and hypopnea indexThe physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment.Universidade Federal de São Paulo (UNIFESP) Departamento de OtorrinolaringologiaUniversidade Federal de São Paulo (UNIFESP) Departamento de Psicobiologia Instituto do SonoUNIFESP, Depto. de OtorrinolaringologiaUNIFESP, Depto. de Psicobiologia Instituto do SonoSciELOAssociação Brasileira de Divulgação CientíficaUniversidade Federal de São Paulo (UNIFESP)Martinho, Fernanda Louise [UNIFESP]Zonato, Adriane Iurck [UNIFESP]Bittencourt, Lia Rita Azeredo [UNIFESP]Soares, Maria Claudia Mattos [UNIFESP]Silva, Rogério Fernandes Nunes da [UNIFESP]Gregório, Luiz Carlos [UNIFESP]Tufik, Sergio [UNIFESP]2015-06-14T13:36:22Z2015-06-14T13:36:22Z2006-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1137-1142application/pdfhttps://dx.doi.org/10.1590/S0100-879X2006000800017Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006.10.1590/S0100-879X2006000800017S0100-879X2006000800017.pdf0100-879XS0100-879X2006000800017https://repositorio.unifesp.br/handle/11600/3188WOS:000239936900017engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T17:57:39Zoai:repositorio.unifesp.br/:11600/3188Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T17:57:39Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
title Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
spellingShingle Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
Martinho, Fernanda Louise [UNIFESP]
Sleep apnea syndrome
Obesity
Surgery
Tonsillectomy
Apnea and hypopnea index
title_short Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
title_full Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
title_fullStr Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
title_full_unstemmed Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
title_sort Obese obstructive sleep apnea patients with tonsil hypertrophy submitted to tonsillectomy
author Martinho, Fernanda Louise [UNIFESP]
author_facet Martinho, Fernanda Louise [UNIFESP]
Zonato, Adriane Iurck [UNIFESP]
Bittencourt, Lia Rita Azeredo [UNIFESP]
Soares, Maria Claudia Mattos [UNIFESP]
Silva, Rogério Fernandes Nunes da [UNIFESP]
Gregório, Luiz Carlos [UNIFESP]
Tufik, Sergio [UNIFESP]
author_role author
author2 Zonato, Adriane Iurck [UNIFESP]
Bittencourt, Lia Rita Azeredo [UNIFESP]
Soares, Maria Claudia Mattos [UNIFESP]
Silva, Rogério Fernandes Nunes da [UNIFESP]
Gregório, Luiz Carlos [UNIFESP]
Tufik, Sergio [UNIFESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Martinho, Fernanda Louise [UNIFESP]
Zonato, Adriane Iurck [UNIFESP]
Bittencourt, Lia Rita Azeredo [UNIFESP]
Soares, Maria Claudia Mattos [UNIFESP]
Silva, Rogério Fernandes Nunes da [UNIFESP]
Gregório, Luiz Carlos [UNIFESP]
Tufik, Sergio [UNIFESP]
dc.subject.por.fl_str_mv Sleep apnea syndrome
Obesity
Surgery
Tonsillectomy
Apnea and hypopnea index
topic Sleep apnea syndrome
Obesity
Surgery
Tonsillectomy
Apnea and hypopnea index
description The physiopathology of obstructive sleep apnea-hypopnea syndrome (OSAHS) is multifactorial and obesity has been shown to be one of the main factors correlated with its occurrence. In obese patients with anatomical alterations of the upper airways it is often difficult to predict success for surgical correction since obesity is a limiting factor. Therefore, the aim of the present study was to evaluate the results of tonsillectomy in a specific group of patients, i.e., obese OSAHS patients with tonsil hypertrophy. Seven OSAHS patients with moderate obesity with obstructive palatine tonsil hypertrophy were submitted to tonsillectomy. All patients were submitted to pre- and postoperative appraisal of body mass index, otorhinolaryngology examination and polysomnography. Patients' average age was 36.4 ± 10.3 years and average preoperative body mass index was 36.6 ± 6.3 kg/m². Postoperative weight did not differ significantly from preoperative weight (P = 0.27). Average preoperative apnea and hypopnea index (AHI) was 81 ± 26/h and postoperative AHI was 23 ± 18/h (P = 0.0005). Average preoperative minimum oxyhemoglobin saturation (SaO2 min) was 69 ± 14% and the postoperative value was 83 ± 3% (P = 0.038). In relation to AHI, 6 (86%) of the 7 patients studied showed a reduction of 50% in relation to preoperative level and of these, 4 (57%) presented AHI of less than 20%. Only one patient presented a reduction of less than 50% in AHI, but even so showed improved SaO2 min. Tonsillectomy treatment for OSAHS in obese patients with obstructive palatine tonsil hypertrophy caused a significant reduction in AHI, with improvement in SaO2 min. This procedure could be eventually considered as an option of treatment for obese OSAHS patients with significant tonsil hypertrophy when continuous positive air pressure therapy is not possible as the first choice of treatment.
publishDate 2006
dc.date.none.fl_str_mv 2006-08-01
2015-06-14T13:36:22Z
2015-06-14T13:36:22Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://dx.doi.org/10.1590/S0100-879X2006000800017
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006.
10.1590/S0100-879X2006000800017
S0100-879X2006000800017.pdf
0100-879X
S0100-879X2006000800017
https://repositorio.unifesp.br/handle/11600/3188
WOS:000239936900017
url https://dx.doi.org/10.1590/S0100-879X2006000800017
https://repositorio.unifesp.br/handle/11600/3188
identifier_str_mv Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 39, n. 8, p. 1137-1142, 2006.
10.1590/S0100-879X2006000800017
S0100-879X2006000800017.pdf
0100-879X
S0100-879X2006000800017
WOS:000239936900017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Medical and Biological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1137-1142
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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