Epidemiology of hepatitis C virus infection

Detalhes bibliográficos
Autor(a) principal: Martins, Tatiana
Data de Publicação: 2011
Outros Autores: Narciso-Schiavon, Janaina Luz [UNIFESP], Schiavon, Leonardo de Lucca [UNIFESP]
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0104-42302011000100024
http://repositorio.unifesp.br/handle/11600/33220
Resumo: Epidemiology of hepatitis C virus infectionHepatitis C is a major cause of chronic liver disease worldwide. There is a significant variation in the prevalence of hepatitis C virus (HCV) infection according to the geographic region studied. These discrepancies reflect not only distinct epidemiological characteristics among the populations, but also differences in the methodologies used for the estimates. Despite scarce data, estimates indicate that Brazil is a country with an intermediate prevalence of HCV infection, ranging from 1% to 2%. the most important risk factors for HCV acquisition include injection drug use, blood product transfusion, organ transplantation, hemodialysis, occupational injury, sexual transmission and vertical transmission. Because there is no vaccine and no post-exposure prophylaxis for HCV, the focus of primary prevention efforts should be identification and removal of the risk factors. in this article we review literature regarding the prevalence of HCV infection, particularly in Brazil. in addition, we discuss the pattern of HCV infection according to the age groups and risk factors for HCV acquisition.
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spelling Epidemiology of hepatitis C virus infectionEpidemiologia da infecção pelo vírus da hepatite CHepatitis Cepidemiologydisease transmissioninfectiousprevalencerisk factorsHepatite Cepidemiologiatransmissão de doença infecciosaprevalênciafatores de riscoEpidemiology of hepatitis C virus infectionHepatitis C is a major cause of chronic liver disease worldwide. There is a significant variation in the prevalence of hepatitis C virus (HCV) infection according to the geographic region studied. These discrepancies reflect not only distinct epidemiological characteristics among the populations, but also differences in the methodologies used for the estimates. Despite scarce data, estimates indicate that Brazil is a country with an intermediate prevalence of HCV infection, ranging from 1% to 2%. the most important risk factors for HCV acquisition include injection drug use, blood product transfusion, organ transplantation, hemodialysis, occupational injury, sexual transmission and vertical transmission. Because there is no vaccine and no post-exposure prophylaxis for HCV, the focus of primary prevention efforts should be identification and removal of the risk factors. in this article we review literature regarding the prevalence of HCV infection, particularly in Brazil. in addition, we discuss the pattern of HCV infection according to the age groups and risk factors for HCV acquisition.A hepatite C é uma das principais causas de doença hepática crônica em todo o mundo. Existe grande variação na prevalência da infecção pelo vírus da hepatite C (HCV) de acordo com a região geográfica estudada, refletindo não só características epidemiológicas distintas entre as populações, mas diferenças nas metodologias utilizadas para a realização das estimativas. Apesar dos dados escassos, estimativas indicam que o Brasil é um país com prevalência intermediária, variando entre 1% e 2%. Os principais fatores de risco para a infecção pelo HCV são a transfusão de hemoderivados de doadores não rastreados com anti-HCV, uso de drogas intravenosas, transplante de órgãos, hemodiálise, transmissão vertical, exposição sexual e ocupacional. Pela ausência de vacina ou profilaxia pós-exposição eficaz, o foco principal da prevenção está no reconhecimento e controle desses fatores de risco. Neste artigo será feita uma revisão da literatura com enfoque na prevalência da hepatite C, especialmente no Brasil. Além disso, serão discutidos aspectos relacionados à distribuição da infecção pelo HCV de acordo com as faixas etárias e também os principais fatores de risco para a hepatite C.Univ Santa Catarina UNISUL, Florianopolis, SC, BrazilUniv Sul Santa Catarina, Programa Posgrad Ciencias Saude, Tubarao, SC, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilWeb of ScienceAssoc Medica BrasileiraUniv Santa Catarina UNISULUniv Sul Santa CatarinaUniversidade Federal de São Paulo (UNIFESP)Martins, TatianaNarciso-Schiavon, Janaina Luz [UNIFESP]Schiavon, Leonardo de Lucca [UNIFESP]2016-01-24T14:05:53Z2016-01-24T14:05:53Z2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion107-112application/pdfapplication/pdfhttp://dx.doi.org/10.1590/S0104-42302011000100024Revista Da Associacao Medica Brasileira. São Paulo: Assoc Medica Brasileira, v. 57, n. 1, p. 107-112, 2011.10.1590/S0104-423020110001000240104-4230S0104-42302011000100024http://repositorio.unifesp.br/handle/11600/33220WOS:000287825600023porengRevista Da Associacao Medica Brasileirainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-31T13:48:53Zoai:repositorio.unifesp.br/:11600/33220Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-31T13:48:53Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Epidemiology of hepatitis C virus infection
Epidemiologia da infecção pelo vírus da hepatite C
title Epidemiology of hepatitis C virus infection
spellingShingle Epidemiology of hepatitis C virus infection
Martins, Tatiana
Hepatitis C
epidemiology
disease transmission
infectious
prevalence
risk factors
Hepatite C
epidemiologia
transmissão de doença infecciosa
prevalência
fatores de risco
title_short Epidemiology of hepatitis C virus infection
title_full Epidemiology of hepatitis C virus infection
title_fullStr Epidemiology of hepatitis C virus infection
title_full_unstemmed Epidemiology of hepatitis C virus infection
title_sort Epidemiology of hepatitis C virus infection
author Martins, Tatiana
author_facet Martins, Tatiana
Narciso-Schiavon, Janaina Luz [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
author_role author
author2 Narciso-Schiavon, Janaina Luz [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Univ Santa Catarina UNISUL
Univ Sul Santa Catarina
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Martins, Tatiana
Narciso-Schiavon, Janaina Luz [UNIFESP]
Schiavon, Leonardo de Lucca [UNIFESP]
dc.subject.por.fl_str_mv Hepatitis C
epidemiology
disease transmission
infectious
prevalence
risk factors
Hepatite C
epidemiologia
transmissão de doença infecciosa
prevalência
fatores de risco
topic Hepatitis C
epidemiology
disease transmission
infectious
prevalence
risk factors
Hepatite C
epidemiologia
transmissão de doença infecciosa
prevalência
fatores de risco
description Epidemiology of hepatitis C virus infectionHepatitis C is a major cause of chronic liver disease worldwide. There is a significant variation in the prevalence of hepatitis C virus (HCV) infection according to the geographic region studied. These discrepancies reflect not only distinct epidemiological characteristics among the populations, but also differences in the methodologies used for the estimates. Despite scarce data, estimates indicate that Brazil is a country with an intermediate prevalence of HCV infection, ranging from 1% to 2%. the most important risk factors for HCV acquisition include injection drug use, blood product transfusion, organ transplantation, hemodialysis, occupational injury, sexual transmission and vertical transmission. Because there is no vaccine and no post-exposure prophylaxis for HCV, the focus of primary prevention efforts should be identification and removal of the risk factors. in this article we review literature regarding the prevalence of HCV infection, particularly in Brazil. in addition, we discuss the pattern of HCV infection according to the age groups and risk factors for HCV acquisition.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
2016-01-24T14:05:53Z
2016-01-24T14:05:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0104-42302011000100024
Revista Da Associacao Medica Brasileira. São Paulo: Assoc Medica Brasileira, v. 57, n. 1, p. 107-112, 2011.
10.1590/S0104-42302011000100024
0104-4230
S0104-42302011000100024
http://repositorio.unifesp.br/handle/11600/33220
WOS:000287825600023
url http://dx.doi.org/10.1590/S0104-42302011000100024
http://repositorio.unifesp.br/handle/11600/33220
identifier_str_mv Revista Da Associacao Medica Brasileira. São Paulo: Assoc Medica Brasileira, v. 57, n. 1, p. 107-112, 2011.
10.1590/S0104-42302011000100024
0104-4230
S0104-42302011000100024
WOS:000287825600023
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv Revista Da Associacao Medica Brasileira
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 107-112
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Assoc Medica Brasileira
publisher.none.fl_str_mv Assoc Medica Brasileira
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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