Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome

Detalhes bibliográficos
Autor(a) principal: Terreri, Maria Teresa R. A. [UNIFESP]
Data de Publicação: 2016
Outros Autores: Bernardo, Wanderley Marques, Len, Claudio Arnaldo [UNIFESP], Almeida da Silva, Clovis Artur, Ribeiro de Magalhaes, Cristina Medeiros, Sacchetti, Silvana B., Leme Ferriani, Virginia Paes, Petry Piotto, Daniela Gerent [UNIFESP], Cavalcanti, Andre de Souza, Pantoja de Moraes, Ana Julia, Sztajnbok, Flavio Roberto, Feitosa de Oliveira, Sheila Knupp, Arruda Campos, Lucia Maria, Bandeira, Marcia, Sena Teixeira Santos, Flavia Patricia, Magalhaes, Claudia Saad
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1016/j.rbr.2015.08.005
http://repositorio.unifesp.br/handle/11600/49532
Resumo: Objective: To establish guidelines based on scientific evidence for the management of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. Description of the evidence collection method: The Guideline was prepared from 5 clinical questions that were structured through PICO (Patient, Intervention or indicator, Comparison and Outcome), to search in key primary scientific information databases. After defining the potential studies to support the recommendations, these were graduated considering their strength of evidence and grade of recommendation. Results: 806 articles were retrieved and evaluated by title and abstract
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spelling Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndromeDiretrizes de conduta e tratamento de síndromes febris periódicas: síndrome de febre periódica, estomatite aftosa, faringite e adeniteSyndrome Of Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical AdenitisGuidelinesChildhoodFeverAutoinflammatory SyndromesPfapa SyndromeCervical AdenitisClinical CharacteristicsTonsillectomyChildrenAdenotonsillectomyOutcomesObjective: To establish guidelines based on scientific evidence for the management of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. Description of the evidence collection method: The Guideline was prepared from 5 clinical questions that were structured through PICO (Patient, Intervention or indicator, Comparison and Outcome), to search in key primary scientific information databases. After defining the potential studies to support the recommendations, these were graduated considering their strength of evidence and grade of recommendation. Results: 806 articles were retrieved and evaluated by title and abstractfrom these, 32 articles were selected to support the recommendations. Recommendations: 1. PFAPA is a diagnosis of exclusion established on clinical grounds, and one must suspect of this problem in children with recurrent and periodic febrile episodes of unknown origin, or with recurrent tonsillitis interspersed with asymptomatic periods, especially in children in good general condition and with preservation of weight and height development2. Laboratory findings are nonspecific. Additional tests do not reveal pathognomonic changes3. The evidence supporting an indication for surgical treatment (tonsillectomy with or without adenoidectomy), is based on two non-blinded randomized clinical trials with small numbers of patients4. The use of prednisone at the onset of fever in patients with PFAPA proved to be an effective strategy. There is still need for more qualified evidence to support its use in patients with PFAPA5. Despite promising results obtained in studies with IL-1 beta inhibitors, such studies are limited to a few case reports. (C) 2015 Elsevier Editora Ltda. All rights reserved.Setor de Reumatologia Pediátrica, Departamento de Pediatria, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, BrasilCentro de Desenvolvimento de Educação Médica, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilUnidade de Reumatologia Pediátrica, Instituto da Criança, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilHospital da Criança de Brasília José Alencar (HCB), Brasília, DF, BrasilIrmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, SP, BrasilServiço de Imunologia, Alergia e Reumatologia Pediátrica, Departamento de Pediatria, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (USP), Ribeirão Preto, SP, BrasilServiço de Reumatologia, Hospital das Clínicas, Universidade Federal de Pernambuco (UFPE), Recife, PE, BrasilUniversidade Federal do Pará (UFPA), Belém, PA, BrasilServiço de Reumatologia, Núcleo de Estudos da Saúde do Adolescente, Universidade do Estado do Rio de Janeiro (Uerj), Rio de Janeiro, RJ, BrasilServiço de Reumatologia Pediátrica, Instituto de Puericultura e Pediatria Martagão Gesteira, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, BrasilHospital Pequeno Príncipe, Curitiba, PR, BrasilServiço de Reumatologia, Hospital das Clínicas, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, BrasilUnidade de Reumatologia Pediátrica, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista (Unesp), Botucatu, SP, BrasilSetor de Reumatologia Pediátrica, Departamento de Pediatria, Universidade Federal de São Paulo (Unifesp), São Paulo, SP, BrasilWeb of ScienceElsevier science inc2019-01-21T10:30:00Z2019-01-21T10:30:00Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion52-57http://dx.doi.org/10.1016/j.rbr.2015.08.005Revista Brasileira De Reumatologia. New york, v. 56, n. 1, p. 52-57, 2016.10.1016/j.rbr.2015.08.005S0482-50042016000100052.pdf0482-5004S0482-50042016000100052http://repositorio.unifesp.br/handle/11600/49532WOS:000374895300009porRevista Brasileira De Reumatologiainfo:eu-repo/semantics/openAccessTerreri, Maria Teresa R. A. [UNIFESP]Bernardo, Wanderley MarquesLen, Claudio Arnaldo [UNIFESP]Almeida da Silva, Clovis ArturRibeiro de Magalhaes, Cristina MedeirosSacchetti, Silvana B.Leme Ferriani, Virginia PaesPetry Piotto, Daniela Gerent [UNIFESP]Cavalcanti, Andre de SouzaPantoja de Moraes, Ana JuliaSztajnbok, Flavio RobertoFeitosa de Oliveira, Sheila KnuppArruda Campos, Lucia MariaBandeira, MarciaSena Teixeira Santos, Flavia PatriciaMagalhaes, Claudia Saadreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-07T21:01:45Zoai:repositorio.unifesp.br/:11600/49532Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652022-02-07T21:01:45Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
Diretrizes de conduta e tratamento de síndromes febris periódicas: síndrome de febre periódica, estomatite aftosa, faringite e adenite
title Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
spellingShingle Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
Terreri, Maria Teresa R. A. [UNIFESP]
Syndrome Of Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis
Guidelines
Childhood
Fever
Autoinflammatory SyndromesPfapa Syndrome
Cervical Adenitis
Clinical Characteristics
Tonsillectomy
Children
Adenotonsillectomy
Outcomes
title_short Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
title_full Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
title_fullStr Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
title_full_unstemmed Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
title_sort Guidelines for the management and treatment of periodic fever syndromes: periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome
author Terreri, Maria Teresa R. A. [UNIFESP]
author_facet Terreri, Maria Teresa R. A. [UNIFESP]
Bernardo, Wanderley Marques
Len, Claudio Arnaldo [UNIFESP]
Almeida da Silva, Clovis Artur
Ribeiro de Magalhaes, Cristina Medeiros
Sacchetti, Silvana B.
Leme Ferriani, Virginia Paes
Petry Piotto, Daniela Gerent [UNIFESP]
Cavalcanti, Andre de Souza
Pantoja de Moraes, Ana Julia
Sztajnbok, Flavio Roberto
Feitosa de Oliveira, Sheila Knupp
Arruda Campos, Lucia Maria
Bandeira, Marcia
Sena Teixeira Santos, Flavia Patricia
Magalhaes, Claudia Saad
author_role author
author2 Bernardo, Wanderley Marques
Len, Claudio Arnaldo [UNIFESP]
Almeida da Silva, Clovis Artur
Ribeiro de Magalhaes, Cristina Medeiros
Sacchetti, Silvana B.
Leme Ferriani, Virginia Paes
Petry Piotto, Daniela Gerent [UNIFESP]
Cavalcanti, Andre de Souza
Pantoja de Moraes, Ana Julia
Sztajnbok, Flavio Roberto
Feitosa de Oliveira, Sheila Knupp
Arruda Campos, Lucia Maria
Bandeira, Marcia
Sena Teixeira Santos, Flavia Patricia
Magalhaes, Claudia Saad
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Terreri, Maria Teresa R. A. [UNIFESP]
Bernardo, Wanderley Marques
Len, Claudio Arnaldo [UNIFESP]
Almeida da Silva, Clovis Artur
Ribeiro de Magalhaes, Cristina Medeiros
Sacchetti, Silvana B.
Leme Ferriani, Virginia Paes
Petry Piotto, Daniela Gerent [UNIFESP]
Cavalcanti, Andre de Souza
Pantoja de Moraes, Ana Julia
Sztajnbok, Flavio Roberto
Feitosa de Oliveira, Sheila Knupp
Arruda Campos, Lucia Maria
Bandeira, Marcia
Sena Teixeira Santos, Flavia Patricia
Magalhaes, Claudia Saad
dc.subject.por.fl_str_mv Syndrome Of Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis
Guidelines
Childhood
Fever
Autoinflammatory SyndromesPfapa Syndrome
Cervical Adenitis
Clinical Characteristics
Tonsillectomy
Children
Adenotonsillectomy
Outcomes
topic Syndrome Of Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis
Guidelines
Childhood
Fever
Autoinflammatory SyndromesPfapa Syndrome
Cervical Adenitis
Clinical Characteristics
Tonsillectomy
Children
Adenotonsillectomy
Outcomes
description Objective: To establish guidelines based on scientific evidence for the management of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. Description of the evidence collection method: The Guideline was prepared from 5 clinical questions that were structured through PICO (Patient, Intervention or indicator, Comparison and Outcome), to search in key primary scientific information databases. After defining the potential studies to support the recommendations, these were graduated considering their strength of evidence and grade of recommendation. Results: 806 articles were retrieved and evaluated by title and abstract
publishDate 2016
dc.date.none.fl_str_mv 2016
2019-01-21T10:30:00Z
2019-01-21T10:30:00Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.rbr.2015.08.005
Revista Brasileira De Reumatologia. New york, v. 56, n. 1, p. 52-57, 2016.
10.1016/j.rbr.2015.08.005
S0482-50042016000100052.pdf
0482-5004
S0482-50042016000100052
http://repositorio.unifesp.br/handle/11600/49532
WOS:000374895300009
url http://dx.doi.org/10.1016/j.rbr.2015.08.005
http://repositorio.unifesp.br/handle/11600/49532
identifier_str_mv Revista Brasileira De Reumatologia. New york, v. 56, n. 1, p. 52-57, 2016.
10.1016/j.rbr.2015.08.005
S0482-50042016000100052.pdf
0482-5004
S0482-50042016000100052
WOS:000374895300009
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira De Reumatologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 52-57
dc.publisher.none.fl_str_mv Elsevier science inc
publisher.none.fl_str_mv Elsevier science inc
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268392896462848

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