Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan

Detalhes bibliográficos
Autor(a) principal: Sakae, Patricia Naomi [UNIFESP]
Data de Publicação: 2017
Tipo de documento: Tese
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5426466
http://repositorio.unifesp.br/handle/11600/50479
Resumo: Introduction: Diets with carbohydrate restriction has been widely used by the population aiming at weight loss. Among them, Dukan diet, with high protein content and carbohydrate and fat restriction has been widely used for weight loss. Objective: To compare nutritional, laboratory and endothelial function parameters in obese subjects submitted to the Dukan diet with those submitted to traditional low calorie diet. Methods: Subjects with obesity classes I or II, from both genders, aging 19 to 65 years, were included in the study and allocated into two groups: Traditional low-calorie diet (n = 17) and Dukan Diet (n = 17). The traditional diet group received counselling according to the recommendations of the Guia Alimentar para a População Brasileira (Ministério da Saúde, 2006) and the Dukan diet group followed the high-protein diet with carbohydrate restriction. Clinical, nutritional, and laboratory evaluations were performed at baseline, 3, 6 and 12 months. The endothelial function was assessed by flow-mediated dilatation of the brachial artery, at same times. Statistical analysis was performed by Student t test for comparison between groups and repeated measure analysis of variance (ANOVA) followed by Tukey test for comparison the values in the times in each group. Results: In the Dukan diet group, there was an imbalance in the food intake of macro and micronutrients with reductions in calories, proteins, carbohydrates, lipids, fibers, saturated, polyunsaturated and monounsaturated fats and magnesium. In the traditional diet group there was reduction only in calories and vitamin B12. After 12 months, it was verified that the Dukan diet was more effective (p<0.05) than traditional diet for the following anthropometric parameters: weight loss (-10.6 kg and -2.9 kg), body mass index (-3.7 kg/m2 and -1.1 kg/m2 ), waist circumference abdominal (-11.2 cm and -2.1 cm), body composition with loss in fat (-5.7 kg and -2.0 kg), lean mass (-4.8 kg and -0.8 kg) and basal metabolic rate (-152 cal and -28 cal). Laboratory changes observed in the Dukan diet group include improvement (p<0.05 vs. baseline) in triglyceride levels (172.40 ± 62.36 mg/dL to 111.90 ± 43.22 mg/dL) and insulin resistance, based on HOMA-IR index (4.98 ± 3.03 to 3.26 ± 2.03, p<0.05 vs. baseline). The glomerular filtration rate decreased in this group (132.50 ± 31.13 mL/min to 113.80 ± 24.25 mL/min, p<0.05 vs. baseline) after 3 months, and no significant change was observed in the endothelial function in any group. Conclusion: The Dukan Diet was more effective than traditional diet for weight loss in the 12-months follow-up in obese subjects. Some improvement on biochemical parameters was observed, without changes in endothelial function.
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spelling Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta DukanNutritional and laboratory evaluation of two programs for weight loss obese individuals: traditional diet and Dukan dietObesityDiet therapyWeight lossDiet, carbohydrate-restrictedNutrition assessmentObesidadeDietoterapiaPerda de pesoDieta com restrição de carboidratosAvaliação nutricionalIntroduction: Diets with carbohydrate restriction has been widely used by the population aiming at weight loss. Among them, Dukan diet, with high protein content and carbohydrate and fat restriction has been widely used for weight loss. Objective: To compare nutritional, laboratory and endothelial function parameters in obese subjects submitted to the Dukan diet with those submitted to traditional low calorie diet. Methods: Subjects with obesity classes I or II, from both genders, aging 19 to 65 years, were included in the study and allocated into two groups: Traditional low-calorie diet (n = 17) and Dukan Diet (n = 17). The traditional diet group received counselling according to the recommendations of the Guia Alimentar para a População Brasileira (Ministério da Saúde, 2006) and the Dukan diet group followed the high-protein diet with carbohydrate restriction. Clinical, nutritional, and laboratory evaluations were performed at baseline, 3, 6 and 12 months. The endothelial function was assessed by flow-mediated dilatation of the brachial artery, at same times. Statistical analysis was performed by Student t test for comparison between groups and repeated measure analysis of variance (ANOVA) followed by Tukey test for comparison the values in the times in each group. Results: In the Dukan diet group, there was an imbalance in the food intake of macro and micronutrients with reductions in calories, proteins, carbohydrates, lipids, fibers, saturated, polyunsaturated and monounsaturated fats and magnesium. In the traditional diet group there was reduction only in calories and vitamin B12. After 12 months, it was verified that the Dukan diet was more effective (p<0.05) than traditional diet for the following anthropometric parameters: weight loss (-10.6 kg and -2.9 kg), body mass index (-3.7 kg/m2 and -1.1 kg/m2 ), waist circumference abdominal (-11.2 cm and -2.1 cm), body composition with loss in fat (-5.7 kg and -2.0 kg), lean mass (-4.8 kg and -0.8 kg) and basal metabolic rate (-152 cal and -28 cal). Laboratory changes observed in the Dukan diet group include improvement (p<0.05 vs. baseline) in triglyceride levels (172.40 ± 62.36 mg/dL to 111.90 ± 43.22 mg/dL) and insulin resistance, based on HOMA-IR index (4.98 ± 3.03 to 3.26 ± 2.03, p<0.05 vs. baseline). The glomerular filtration rate decreased in this group (132.50 ± 31.13 mL/min to 113.80 ± 24.25 mL/min, p<0.05 vs. baseline) after 3 months, and no significant change was observed in the endothelial function in any group. Conclusion: The Dukan Diet was more effective than traditional diet for weight loss in the 12-months follow-up in obese subjects. Some improvement on biochemical parameters was observed, without changes in endothelial function.Introdução: Dietas com baixo consumo de carboidratos têm sido utilizadas visando perda de peso. Dentre elas, a dieta Dukan, com restrição de carboidratos e de gorduras e alta concentração de proteínas, tem sido amplamente utilizada para emagrecimento. Objetivo: Comparar parâmetros nutricionais, laboratoriais e função endotelial em indivíduos obesos submetidos à dieta Dukan com os submetidos à dieta tradicional de baixa caloria. Métodos: Foram incluídos participantes de ambos os gêneros, com idades entre 19 e 65 anos, obesidades graus I ou II, distribuídos em dois grupos: Dieta tradicional de baixa caloria (n=17) e dieta Dukan (n=17). O grupo dieta tradicional recebeu as recomendações do Guia Alimentar para a População Brasileira (Ministério da Saúde, 2006) e o grupo dieta Dukan seguiu dieta hiperproteica com restrição de carboidrato. Os participantes foram avaliados nos tempos basal, 3, 6 e 12 meses, com avaliações clínica, nutricional, laboratoriais e função endotelial avaliada pela dilatação mediada pelo fluxo da artéria braquial. Análise estatística foi realizada por teste t de Student para comparação entre grupos e teste ANOVA de medidas repetidas seguida por teste de Tukey para comparação entre os tempos em cada grupo. Resultados: O grupo dieta Dukan apresentou alteração no consumo alimentar de macro e micronutrientes com aumento de proteínas e redução em calorias, carboidratos, lipídios, fibras, gorduras saturadas, poliinsaturadas, monoinsaturadas e magnésio. No grupo dieta tradicional houve redução apenas em calorias, carboidratos e vitamina B12. Após 12 meses, a dieta Dukan foi mais efetiva do que a dieta tradicional (p<0,05) para os seguintes parâmetros nutricionais, respectivamente: redução no peso (-10,6 kg e -2,9 kg), índice de massa corpórea (-3,7 kg/m2 e -1,1 kg/m2 ), circunferência abdominal (-11,2 cm e -2,1 cm), composição corporal com perda de gordura (-5,7 kg e -2,0 kg), massa magra (-4,8 kg e -0,8 kg) e taxa metabólica basal (-152 cal e -28 cal). Houve melhora (p<0,05 vs. basal) para os participantes do grupo dieta Dukan nos níveis de triglicérides (172,40 ± 62,36 mg/dL para 111,90 ± 43,22 mg/dL) e na resistência insulínica avaliada pelo índice de HOMA-IR (4,98 ± 3,03 para 3,26 ± 2,03). A taxa de filtração glomerular diminuiu neste grupo após 3 meses (132,50 ± 31,13 mL/min para 113,80 ± 24,25 mL/min, p<0,05 vs. basal) e a função endotelial não se modificou em relação ao basal em nenhum dos grupos. Conclusão: A dieta Dukan mostrou mais efetiva do que a dieta tradicional para perda de peso em pacientes obesos ao longo de 12 meses. Melhora em alguns parâmetros bioquímicos foram observados, sem alteração na função endotelial.Dados abertos - Sucupira - Teses e dissertações (2017)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Federal de São Paulo (UNIFESP)Ihara, Silvia Saiuli Miki [UNIFESP]Fonseca, Francisco Antônio Helfenstein [UNIFESP]Bianco, Henrique Tria [UNIFESP]http://lattes.cnpq.br/2393476657163442http://lattes.cnpq.br/8007263883467875http://lattes.cnpq.br/6248521668115511http://lattes.cnpq.br/7894940635195736Universidade Federal de São Paulo (UNIFESP)Sakae, Patricia Naomi [UNIFESP]2019-06-19T14:57:58Z2019-06-19T14:57:58Z2017-03-09info:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/publishedVersion100 f.application/pdfhttps://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5426466http://repositorio.unifesp.br/handle/11600/50479porSão Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-02T17:39:41Zoai:repositorio.unifesp.br/:11600/50479Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-02T17:39:41Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
Nutritional and laboratory evaluation of two programs for weight loss obese individuals: traditional diet and Dukan diet
title Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
spellingShingle Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
Sakae, Patricia Naomi [UNIFESP]
Obesity
Diet therapy
Weight loss
Diet, carbohydrate-restricted
Nutrition assessment
Obesidade
Dietoterapia
Perda de peso
Dieta com restrição de carboidratos
Avaliação nutricional
title_short Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
title_full Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
title_fullStr Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
title_full_unstemmed Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
title_sort Avaliação nutricional e laboratorial de dois programas para perda de peso em indivíduos obesos: dieta tradicional X dieta Dukan
author Sakae, Patricia Naomi [UNIFESP]
author_facet Sakae, Patricia Naomi [UNIFESP]
author_role author
dc.contributor.none.fl_str_mv Ihara, Silvia Saiuli Miki [UNIFESP]
Fonseca, Francisco Antônio Helfenstein [UNIFESP]
Bianco, Henrique Tria [UNIFESP]
http://lattes.cnpq.br/2393476657163442
http://lattes.cnpq.br/8007263883467875
http://lattes.cnpq.br/6248521668115511
http://lattes.cnpq.br/7894940635195736
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Sakae, Patricia Naomi [UNIFESP]
dc.subject.por.fl_str_mv Obesity
Diet therapy
Weight loss
Diet, carbohydrate-restricted
Nutrition assessment
Obesidade
Dietoterapia
Perda de peso
Dieta com restrição de carboidratos
Avaliação nutricional
topic Obesity
Diet therapy
Weight loss
Diet, carbohydrate-restricted
Nutrition assessment
Obesidade
Dietoterapia
Perda de peso
Dieta com restrição de carboidratos
Avaliação nutricional
description Introduction: Diets with carbohydrate restriction has been widely used by the population aiming at weight loss. Among them, Dukan diet, with high protein content and carbohydrate and fat restriction has been widely used for weight loss. Objective: To compare nutritional, laboratory and endothelial function parameters in obese subjects submitted to the Dukan diet with those submitted to traditional low calorie diet. Methods: Subjects with obesity classes I or II, from both genders, aging 19 to 65 years, were included in the study and allocated into two groups: Traditional low-calorie diet (n = 17) and Dukan Diet (n = 17). The traditional diet group received counselling according to the recommendations of the Guia Alimentar para a População Brasileira (Ministério da Saúde, 2006) and the Dukan diet group followed the high-protein diet with carbohydrate restriction. Clinical, nutritional, and laboratory evaluations were performed at baseline, 3, 6 and 12 months. The endothelial function was assessed by flow-mediated dilatation of the brachial artery, at same times. Statistical analysis was performed by Student t test for comparison between groups and repeated measure analysis of variance (ANOVA) followed by Tukey test for comparison the values in the times in each group. Results: In the Dukan diet group, there was an imbalance in the food intake of macro and micronutrients with reductions in calories, proteins, carbohydrates, lipids, fibers, saturated, polyunsaturated and monounsaturated fats and magnesium. In the traditional diet group there was reduction only in calories and vitamin B12. After 12 months, it was verified that the Dukan diet was more effective (p<0.05) than traditional diet for the following anthropometric parameters: weight loss (-10.6 kg and -2.9 kg), body mass index (-3.7 kg/m2 and -1.1 kg/m2 ), waist circumference abdominal (-11.2 cm and -2.1 cm), body composition with loss in fat (-5.7 kg and -2.0 kg), lean mass (-4.8 kg and -0.8 kg) and basal metabolic rate (-152 cal and -28 cal). Laboratory changes observed in the Dukan diet group include improvement (p<0.05 vs. baseline) in triglyceride levels (172.40 ± 62.36 mg/dL to 111.90 ± 43.22 mg/dL) and insulin resistance, based on HOMA-IR index (4.98 ± 3.03 to 3.26 ± 2.03, p<0.05 vs. baseline). The glomerular filtration rate decreased in this group (132.50 ± 31.13 mL/min to 113.80 ± 24.25 mL/min, p<0.05 vs. baseline) after 3 months, and no significant change was observed in the endothelial function in any group. Conclusion: The Dukan Diet was more effective than traditional diet for weight loss in the 12-months follow-up in obese subjects. Some improvement on biochemical parameters was observed, without changes in endothelial function.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-09
2019-06-19T14:57:58Z
2019-06-19T14:57:58Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format doctoralThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5426466
http://repositorio.unifesp.br/handle/11600/50479
url https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5426466
http://repositorio.unifesp.br/handle/11600/50479
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv 100 f.
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dc.coverage.none.fl_str_mv São Paulo
dc.publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
publisher.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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