Overactive bladder-18 years - Part II
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/57829 http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0367 |
Resumo: | Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics - pillars of the overactive bladder pharmacotherapy - started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning - as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder - 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder. |
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Truzzi, Jose Carlos [UNIFESP]Gomes, Cristiano MendesBezerra, Carlos A.Plata, Ivan MauricioCampos, JoseGarrido, Gustavo LuisAlmeida, Fernando G. [UNIFESP]Averbeck, Marcio AugustoFornari, AlexandreSalazar, AnibalDell'Oro, ArturoCintra, CaioRicetto Sacomani, Carlos AlbertoTapia, Juan PabloBrambila, EduardoLongo, Emilio MiguelRocha, Flavio TrigoCoutinho, FranciscoFavre, GabrielGarcia, Jose AntonioCastano, JuanReyes, MiguelLeyton, Rodrigo EugenioFerreira, Ruiter SilvaDuran, SergioLopez, VandaReges, Ricardo2020-08-21T17:00:00Z2020-08-21T17:00:00Z2016International Braz J Urol. Rio De Janeiro, v. 42, n. 2, p. 199-214, 2016.1677-5538https://repositorio.unifesp.br/handle/11600/57829http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0367S1677-55382016000200199-en.pdfS1677-5538201600020019910.1590/S1677-5538.IBJU.2015.0367WOS:000375604900006Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics - pillars of the overactive bladder pharmacotherapy - started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning - as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder - 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder.Univ Fed Sao Paulo, EPM, Sao Paulo, SP, BrazilUniv Sao Paulo, Dept Urol, BR-05508 Sao Paulo, SP, BrazilFac Med ABC, Dept Urol, Sao Paulo, SP, BrazilUniv Los Andes, Dept Urol, Bogota, ColombiaEscuela Med Mil, Dept Urol, Mexico City, DF, MexicoHosp Clin Jose San Martin, Catedra Urol, Buenos Aires, DF, ArgentinaMae de Deus Ctr Hosp, Dept Urol, Porto Alegre, RS, BrazilUniv Fed Ciencias Saude Porto Alegre, Porto Alegre, RS, BrazilAC Camargo Hosp, Dept Urol, Sao Paulo, SP, BrazilHosp Clinico Fuerza Area Chile, Santiago, ChileInst Mexicano Seguro Social, Mexico City, DF, MexicoHosp Souza Aguiar, Dept Urol, Rio De Janeiro, RJ, BrazilComplejo Med Policial Churruca Visca, Serv Urol, Buenos Aires, DF, ArgentinaCtr Policlin Valencia Vina, Valencia, VenezuelaHosp Pablo Tobon Uribe, Medellin, ColombiaClin Indisa, Serv Urol, Providencia, ChileCtr Reabilitacao & Readaptacao Dr Henriqe Santill, Goiania, Go, BrazilHosp Univ Caracas, Serv Urol, Caracas, VenezuelaUniv Fed Ceara, Div Urol, Fortaleza, Ceara, BrazilUniv Fed Sao Paulo, EPM, Sao Paulo, SP, BrazilWeb of Science199-214engBrazilian Soc UrolInternational Braz J UrolOveractive BladderMuscarinic AntagonistsBeta-adrenergic agonistsBotulinum ToxinSacral neuromodulationUrodynamicsOveractive bladder-18 years - Part IIinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRio De Janeiro422info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1677-55382016000200199-en.pdfapplication/pdf203934${dspace.ui.url}/bitstream/11600/57829/1/S1677-55382016000200199-en.pdf00f1e7d6ac57b0fb4d333ecf38471150MD51open accessTEXTS1677-55382016000200199-en.pdf.txtS1677-55382016000200199-en.pdf.txtExtracted texttext/plain75668${dspace.ui.url}/bitstream/11600/57829/2/S1677-55382016000200199-en.pdf.txtd15d99f9739d1db88d085b173927de39MD52open accessTHUMBNAILS1677-55382016000200199-en.pdf.jpgS1677-55382016000200199-en.pdf.jpgIM Thumbnailimage/jpeg6360${dspace.ui.url}/bitstream/11600/57829/4/S1677-55382016000200199-en.pdf.jpgda50e6baa33f6d1521ab941e689aa228MD54open access11600/578292022-07-31 19:53:43.751open accessoai:repositorio.unifesp.br:11600/57829Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-07-31T22:53:43Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Overactive bladder-18 years - Part II |
title |
Overactive bladder-18 years - Part II |
spellingShingle |
Overactive bladder-18 years - Part II Truzzi, Jose Carlos [UNIFESP] Overactive Bladder Muscarinic Antagonists Beta-adrenergic agonists Botulinum Toxin Sacral neuromodulation Urodynamics |
title_short |
Overactive bladder-18 years - Part II |
title_full |
Overactive bladder-18 years - Part II |
title_fullStr |
Overactive bladder-18 years - Part II |
title_full_unstemmed |
Overactive bladder-18 years - Part II |
title_sort |
Overactive bladder-18 years - Part II |
author |
Truzzi, Jose Carlos [UNIFESP] |
author_facet |
Truzzi, Jose Carlos [UNIFESP] Gomes, Cristiano Mendes Bezerra, Carlos A. Plata, Ivan Mauricio Campos, Jose Garrido, Gustavo Luis Almeida, Fernando G. [UNIFESP] Averbeck, Marcio Augusto Fornari, Alexandre Salazar, Anibal Dell'Oro, Arturo Cintra, Caio Ricetto Sacomani, Carlos Alberto Tapia, Juan Pablo Brambila, Eduardo Longo, Emilio Miguel Rocha, Flavio Trigo Coutinho, Francisco Favre, Gabriel Garcia, Jose Antonio Castano, Juan Reyes, Miguel Leyton, Rodrigo Eugenio Ferreira, Ruiter Silva Duran, Sergio Lopez, Vanda Reges, Ricardo |
author_role |
author |
author2 |
Gomes, Cristiano Mendes Bezerra, Carlos A. Plata, Ivan Mauricio Campos, Jose Garrido, Gustavo Luis Almeida, Fernando G. [UNIFESP] Averbeck, Marcio Augusto Fornari, Alexandre Salazar, Anibal Dell'Oro, Arturo Cintra, Caio Ricetto Sacomani, Carlos Alberto Tapia, Juan Pablo Brambila, Eduardo Longo, Emilio Miguel Rocha, Flavio Trigo Coutinho, Francisco Favre, Gabriel Garcia, Jose Antonio Castano, Juan Reyes, Miguel Leyton, Rodrigo Eugenio Ferreira, Ruiter Silva Duran, Sergio Lopez, Vanda Reges, Ricardo |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Truzzi, Jose Carlos [UNIFESP] Gomes, Cristiano Mendes Bezerra, Carlos A. Plata, Ivan Mauricio Campos, Jose Garrido, Gustavo Luis Almeida, Fernando G. [UNIFESP] Averbeck, Marcio Augusto Fornari, Alexandre Salazar, Anibal Dell'Oro, Arturo Cintra, Caio Ricetto Sacomani, Carlos Alberto Tapia, Juan Pablo Brambila, Eduardo Longo, Emilio Miguel Rocha, Flavio Trigo Coutinho, Francisco Favre, Gabriel Garcia, Jose Antonio Castano, Juan Reyes, Miguel Leyton, Rodrigo Eugenio Ferreira, Ruiter Silva Duran, Sergio Lopez, Vanda Reges, Ricardo |
dc.subject.eng.fl_str_mv |
Overactive Bladder Muscarinic Antagonists Beta-adrenergic agonists Botulinum Toxin Sacral neuromodulation Urodynamics |
topic |
Overactive Bladder Muscarinic Antagonists Beta-adrenergic agonists Botulinum Toxin Sacral neuromodulation Urodynamics |
description |
Traditionally, the treatment of overactive bladder syndrome has been based on the use of oral medications with the purpose of reestablishing the detrusor stability. The recent better understanding of the urothelial physiology fostered conceptual changes, and the oral anticholinergics - pillars of the overactive bladder pharmacotherapy - started to be not only recognized for their properties of inhibiting the detrusor contractile activity, but also their action on the bladder afference, and therefore, on the reduction of the symptoms that constitute the syndrome. Beta-adrenergic agonists, which were recently added to the list of drugs for the treatment of overactive bladder, still wait for a definitive positioning - as either a second-line therapy or an adjuvant to oral anticholinergics. Conservative treatment failure, whether due to unsatisfactory results or the presence of adverse side effects, define it as refractory overactive bladder. In this context, the intravesical injection of botulinum toxin type A emerged as an effective option for the existing gap between the primary measures and more complex procedures such as bladder augmentation. Sacral neuromodulation, described three decades ago, had its indication reinforced in this overactive bladder era. Likewise, the electric stimulation of the tibial nerve is now a minimally invasive alternative to treat those with refractory overactive bladder. The results of the systematic literature review on the oral pharmacological treatment and the treatment of refractory overactive bladder gave rise to this second part of the review article Overactive Bladder - 18 years, prepared during the 1st Latin-American Consultation on Overactive Bladder. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016 |
dc.date.accessioned.fl_str_mv |
2020-08-21T17:00:00Z |
dc.date.available.fl_str_mv |
2020-08-21T17:00:00Z |
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info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
International Braz J Urol. Rio De Janeiro, v. 42, n. 2, p. 199-214, 2016. |
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https://repositorio.unifesp.br/handle/11600/57829 http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0367 |
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1677-5538 |
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S1677-55382016000200199-en.pdf |
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S1677-55382016000200199 |
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10.1590/S1677-5538.IBJU.2015.0367 |
dc.identifier.wos.none.fl_str_mv |
WOS:000375604900006 |
identifier_str_mv |
International Braz J Urol. Rio De Janeiro, v. 42, n. 2, p. 199-214, 2016. 1677-5538 S1677-55382016000200199-en.pdf S1677-55382016000200199 10.1590/S1677-5538.IBJU.2015.0367 WOS:000375604900006 |
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https://repositorio.unifesp.br/handle/11600/57829 http://dx.doi.org/10.1590/S1677-5538.IBJU.2015.0367 |
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Brazilian Soc Urol |
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Brazilian Soc Urol |
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