Influência do trauma cirúrgico no comportamento dos níveis séricos de albumina após cirurgia da coluna vertebral

• Autor(a) principal: Luciano, Rafael Paiva [UNIFESP]
• Data de Publicação: 2010
• Outros Autores: Leite, Marcio Squassoni [UNIFESP], Martins, Délio Eulálio [UNIFESP], Wajchenberg, Marcelo [UNIFESP], Puertas, Eduardo Barros [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S1808-18512010000400011; http://repositorio.unifesp.br/handle/11600/6069
• topic: Serum albumin; Surgical procedures; operative; Spine; Spinal diseases; Albumina sérica; Procedimentos cirúrgicos operatórios; Coluna vertebral; Doenças da Coluna Vertebral

OBJECTIVE: to evaluate the variation of serum albumin concentration in surgery of the spine and its relation to clinical effects in the postoperative. METHODS: prospective observational study on the values of serum albumin of 55 patients undergoing spine surgery.Blood samples were collected one day before and 24 hours after the procedure. The paired t test was performed to evaluate the change parameters albumin, hemoglobin and hematocrit. The presence of association between the degree of variation in levels of albumin (<1 g/dL or >1 g/dL) and the variables of interest: complications, transfusions, procedures performed, patients' age and sex and diagnosis were assessed by χ2 test or the χ2 likelihood ratio when appropriate. RESULTS: the average reduction of this protein was of 0.58 g/dL, ranging from 0 to 1.8 g/dL. Of the patients, 78.2% showed albumin values in the postoperative period below the normal range. Only two patients presented with complications during the 30 days of follow-up. The group with the correction of deformities showed 100% of patients with variation of >1 g/dL. CONCLUSION: there was an influence of the surgical trauma in reducing serum albumin, on average, 0.58 g/dL in surgery of the spine. It was not possible to associate this decrease to complications in the postoperative period after 30 days of follow-up of these patients.