Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise

Detalhes bibliográficos
Autor(a) principal: Batista, Marcus Sabry Azar [UNIFESP]
Data de Publicação: 1999
Outros Autores: Sesso, Ricardo de Castro Cintra [UNIFESP], Reis-Filho, João Batista dos [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0037-86821999000600011
http://repositorio.unifesp.br/handle/11600/853
Resumo: We reviewed the cerebrospinal fluid (CSF) syndromes of 100 consecutive HIV-positive patients presenting acute consciousness compromise in emergency rooms, and correlated them with clinical data. The most frequent CSF syndromes were: absolute protein-cytological dissociation (21), viral (19), neurocryptococcosis (7), relative protein-cytological dissociation (6) and septic (4), moderate hypoglycorrachia (4), severe hypoglycorrachia (4) and hydroelectrolytic disturbance (3). One fifth of the patients had CSF syndromes considered sufficient for diagnosis or an immediate clinical decision. The most common clinical data were infective and neurological. There was little correlation between the clinical data and the CSF syndromes. We conclude that in HIV-positive individuals presenting acute consciousness disturbances there are frequently non-specific results in the CSF analysis that must be weighed against a detailed history and thorough physical examination. Taking this into account, in about one fifth of cases the CSF analysis can offer useful information for treatment.
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spelling Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromiseSíndromes liquóricas em pacientes HIV positivos com comprometimento agudo da consciênciaCerebrospinal fluidDeliriumSomnolenceAIDSHIVLíquorDeliriumSonolênciaAIDSHIVWe reviewed the cerebrospinal fluid (CSF) syndromes of 100 consecutive HIV-positive patients presenting acute consciousness compromise in emergency rooms, and correlated them with clinical data. The most frequent CSF syndromes were: absolute protein-cytological dissociation (21), viral (19), neurocryptococcosis (7), relative protein-cytological dissociation (6) and septic (4), moderate hypoglycorrachia (4), severe hypoglycorrachia (4) and hydroelectrolytic disturbance (3). One fifth of the patients had CSF syndromes considered sufficient for diagnosis or an immediate clinical decision. The most common clinical data were infective and neurological. There was little correlation between the clinical data and the CSF syndromes. We conclude that in HIV-positive individuals presenting acute consciousness disturbances there are frequently non-specific results in the CSF analysis that must be weighed against a detailed history and thorough physical examination. Taking this into account, in about one fifth of cases the CSF analysis can offer useful information for treatment.Revisamos as síndromes liquóricas de 100 pacientes HIV-positivos apresentando comprometimento agudo da consciência em pronto-socorro, as correlacionando com dados clínicos. As síndromes mais frequentes foram: dissociação proteino-citológica absoluta (21), viral (19), neurocriptococose (7), dissociação proteino-citológica relativa (6) e séptica (4), hipoglicorraquia moderada (4%), hipoglicorraquia severa (4%), distúrbio hidroeletrolítico (3%). Um quinto dos pacientes apresentou síndromes liquóricas consideradas suficientes para um diagnóstico ou uma conduta imediata. Os dados clínicos mais comuns foram infecciosos e neurológicos. Houve pouca correlação entre os dados clínicos e as síndromes liquóricas. Comparado a dados de literatura, HIV-positivos tem menor chance de resultados decisivos no exame de líquor. Nós concluimos que, em pacientes HIV-positivos, que se apresentam com alterações agudas da consciência, frequentemente há resultados inespecíficos no líquor, o que deve ser julgado em função de uma história clínica e exame físicos detalhados.Universidade Federal de São Paulo (UNIFESP)UNIFESPSciELOSociedade Brasileira de Medicina Tropical - SBMTUniversidade Federal de São Paulo (UNIFESP)Batista, Marcus Sabry Azar [UNIFESP]Sesso, Ricardo de Castro Cintra [UNIFESP]Reis-Filho, João Batista dos [UNIFESP]2015-06-14T13:24:57Z2015-06-14T13:24:57Z1999-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion683-688application/pdfhttp://dx.doi.org/10.1590/S0037-86821999000600011Revista da Sociedade Brasileira de Medicina Tropical. Sociedade Brasileira de Medicina Tropical - SBMT, v. 32, n. 6, p. 683-688, 1999.10.1590/S0037-86821999000600011S0037-86821999000600011.pdf0037-8682S0037-86821999000600011http://repositorio.unifesp.br/handle/11600/853engRevista da Sociedade Brasileira de Medicina Tropicalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T20:05:51Zoai:repositorio.unifesp.br/:11600/853Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T20:05:51Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
Síndromes liquóricas em pacientes HIV positivos com comprometimento agudo da consciência
title Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
spellingShingle Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
Batista, Marcus Sabry Azar [UNIFESP]
Cerebrospinal fluid
Delirium
Somnolence
AIDS
HIV
Líquor
Delirium
Sonolência
AIDS
HIV
title_short Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
title_full Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
title_fullStr Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
title_full_unstemmed Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
title_sort Cerebrospinal fluid syndromes in HIV-positive patients with acute consciousness compromise
author Batista, Marcus Sabry Azar [UNIFESP]
author_facet Batista, Marcus Sabry Azar [UNIFESP]
Sesso, Ricardo de Castro Cintra [UNIFESP]
Reis-Filho, João Batista dos [UNIFESP]
author_role author
author2 Sesso, Ricardo de Castro Cintra [UNIFESP]
Reis-Filho, João Batista dos [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Batista, Marcus Sabry Azar [UNIFESP]
Sesso, Ricardo de Castro Cintra [UNIFESP]
Reis-Filho, João Batista dos [UNIFESP]
dc.subject.por.fl_str_mv Cerebrospinal fluid
Delirium
Somnolence
AIDS
HIV
Líquor
Delirium
Sonolência
AIDS
HIV
topic Cerebrospinal fluid
Delirium
Somnolence
AIDS
HIV
Líquor
Delirium
Sonolência
AIDS
HIV
description We reviewed the cerebrospinal fluid (CSF) syndromes of 100 consecutive HIV-positive patients presenting acute consciousness compromise in emergency rooms, and correlated them with clinical data. The most frequent CSF syndromes were: absolute protein-cytological dissociation (21), viral (19), neurocryptococcosis (7), relative protein-cytological dissociation (6) and septic (4), moderate hypoglycorrachia (4), severe hypoglycorrachia (4) and hydroelectrolytic disturbance (3). One fifth of the patients had CSF syndromes considered sufficient for diagnosis or an immediate clinical decision. The most common clinical data were infective and neurological. There was little correlation between the clinical data and the CSF syndromes. We conclude that in HIV-positive individuals presenting acute consciousness disturbances there are frequently non-specific results in the CSF analysis that must be weighed against a detailed history and thorough physical examination. Taking this into account, in about one fifth of cases the CSF analysis can offer useful information for treatment.
publishDate 1999
dc.date.none.fl_str_mv 1999-12-01
2015-06-14T13:24:57Z
2015-06-14T13:24:57Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0037-86821999000600011
Revista da Sociedade Brasileira de Medicina Tropical. Sociedade Brasileira de Medicina Tropical - SBMT, v. 32, n. 6, p. 683-688, 1999.
10.1590/S0037-86821999000600011
S0037-86821999000600011.pdf
0037-8682
S0037-86821999000600011
http://repositorio.unifesp.br/handle/11600/853
url http://dx.doi.org/10.1590/S0037-86821999000600011
http://repositorio.unifesp.br/handle/11600/853
identifier_str_mv Revista da Sociedade Brasileira de Medicina Tropical. Sociedade Brasileira de Medicina Tropical - SBMT, v. 32, n. 6, p. 683-688, 1999.
10.1590/S0037-86821999000600011
S0037-86821999000600011.pdf
0037-8682
S0037-86821999000600011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista da Sociedade Brasileira de Medicina Tropical
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 683-688
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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