Inequality in pediatric kidney transplantation in Brazil

• Autor(a) principal: Koch Nogueira, Paulo Cesar [UNIFESP]
• Data de Publicação: 2016
• Outros Autores: Camargo de Carvalho, Maria Fernanda, Feltran, Luciana de Santis [UNIFESP], Konstantyner, Tulio [UNIFESP], Sesso, Ricardo [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1007/s00467-015-3226-z; https://repositorio.unifesp.br/handle/11600/57916
• topic: Kidney transplantation; Epidemiology; Demography; Supply and distribution; Pediatrics

Background The aim of this study was to describe the access and factors associated with kidney transplantation for children in different regions of Brazil. Methods We analyzed a cohort of 1211 children enrolled on the transplant list from January 2011 to December of 2013. We fitted regression models to investigate factors associated with: (a) undergoing kidney transplantation from a deceased donor, and (b) being removed from the waiting list. Results The incidence of transplantation was uneven across regions, with the lowest rate at 0.4 per million age-related population (pmarp) in the Midwest and the highest incidence rate of 8.3 cases pmarp in the South. Children from the North and the Midwest regions had a 3-4 times lower probability of undergoing a deceased donor transplant (p < 0.05). Apart from the geographic region, age of recipients and GDP influenced the outcome. The likelihood of undergoing transplantation was very low in the youngest children in the North and Midwest. The number of transplant centers was not associated with either outcome. Conclusions Factors of inequality in transplantation in Brazil are of macroeconomic origin, but there is room to reduce inequalities. Training existing transplant center professionals in the care of children could diminish the discrepancies.