Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Bioscience journal (Online) |
Texto Completo: | https://seer.ufu.br/index.php/biosciencejournal/article/view/28247 |
Resumo: | Affective disorders have been linked to abnormal biological rhythms. Depression- and anxiety-related behaviors can be altered following changes of daily periods of environmental light. The aim of this study was to investigate the effect of daily light cycle on both anxiety- and depressive-like behaviors of rats. Wistar male rats were exposed to constant dark or constant light during one week and compared to control animals exposed to 12/12h light/dark cycle regarding to anxiety-like behaviors and general activity on open field test and depressive-like behaviors on the forced swimming test. Data showed that rats exposed to one week of constant light exhibited increased number of quadrants crossed in the open field. No change on anxiety-like behaviors (time and quadrants crossed in the center of apparatus) was observed in the open field test. One week of constant dark increased the time of immobility behavior in the forced swimming test relative to control 12/12h light/dark treatment. Therefore, one week of continuous light induced locomotor hyperactivity and one week of continuous dark induced depressive-like behaviors following reestablishment of normal 12/12h light/dark cycle. Such data demonstrate the importance of light/dark environmental rhythm on mood changes and the significance of light/dark cycle control on behavioral studies. |
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Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats Anxiety. Depression. Locomotor activity. Circadian rhythmBiological SciencesAffective disorders have been linked to abnormal biological rhythms. Depression- and anxiety-related behaviors can be altered following changes of daily periods of environmental light. The aim of this study was to investigate the effect of daily light cycle on both anxiety- and depressive-like behaviors of rats. Wistar male rats were exposed to constant dark or constant light during one week and compared to control animals exposed to 12/12h light/dark cycle regarding to anxiety-like behaviors and general activity on open field test and depressive-like behaviors on the forced swimming test. Data showed that rats exposed to one week of constant light exhibited increased number of quadrants crossed in the open field. No change on anxiety-like behaviors (time and quadrants crossed in the center of apparatus) was observed in the open field test. One week of constant dark increased the time of immobility behavior in the forced swimming test relative to control 12/12h light/dark treatment. Therefore, one week of continuous light induced locomotor hyperactivity and one week of continuous dark induced depressive-like behaviors following reestablishment of normal 12/12h light/dark cycle. Such data demonstrate the importance of light/dark environmental rhythm on mood changes and the significance of light/dark cycle control on behavioral studies.EDUFU2015-11-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.ufu.br/index.php/biosciencejournal/article/view/2824710.14393/BJ-v31n6a2015-28247Bioscience Journal ; Vol. 31 No. 6 (2015): Nov./Dec.; 1837-184Bioscience Journal ; v. 31 n. 6 (2015): Nov./Dec.; 1837-1841981-3163reponame:Bioscience journal (Online)instname:Universidade Federal de Uberlândia (UFU)instacron:UFUenghttps://seer.ufu.br/index.php/biosciencejournal/article/view/28247/17403Brazil; ContemporaryCopyright (c) 2015 Macelo Tadeu Marin, Túlio Teixeira Araújo, Marina Monteiro Figueiredo Rezende, Renata Ribeiro-Barbosahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarin, Macelo TadeuAraújo, Túlio TeixeiraRezende, Marina Monteiro FigueiredoRibeiro-Barbosa, Renata2022-05-10T13:12:43Zoai:ojs.www.seer.ufu.br:article/28247Revistahttps://seer.ufu.br/index.php/biosciencejournalPUBhttps://seer.ufu.br/index.php/biosciencejournal/oaibiosciencej@ufu.br||1981-31631516-3725opendoar:2022-05-10T13:12:43Bioscience journal (Online) - Universidade Federal de Uberlândia (UFU)false |
dc.title.none.fl_str_mv |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
title |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
spellingShingle |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats Marin, Macelo Tadeu Anxiety. Depression. Locomotor activity. Circadian rhythm Biological Sciences |
title_short |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
title_full |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
title_fullStr |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
title_full_unstemmed |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
title_sort |
Behavioral alterations induced by absence of circadian light rhythm: effects of constant light or constant dark on depression-like behaviors and locomotor activity in rats |
author |
Marin, Macelo Tadeu |
author_facet |
Marin, Macelo Tadeu Araújo, Túlio Teixeira Rezende, Marina Monteiro Figueiredo Ribeiro-Barbosa, Renata |
author_role |
author |
author2 |
Araújo, Túlio Teixeira Rezende, Marina Monteiro Figueiredo Ribeiro-Barbosa, Renata |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Marin, Macelo Tadeu Araújo, Túlio Teixeira Rezende, Marina Monteiro Figueiredo Ribeiro-Barbosa, Renata |
dc.subject.por.fl_str_mv |
Anxiety. Depression. Locomotor activity. Circadian rhythm Biological Sciences |
topic |
Anxiety. Depression. Locomotor activity. Circadian rhythm Biological Sciences |
description |
Affective disorders have been linked to abnormal biological rhythms. Depression- and anxiety-related behaviors can be altered following changes of daily periods of environmental light. The aim of this study was to investigate the effect of daily light cycle on both anxiety- and depressive-like behaviors of rats. Wistar male rats were exposed to constant dark or constant light during one week and compared to control animals exposed to 12/12h light/dark cycle regarding to anxiety-like behaviors and general activity on open field test and depressive-like behaviors on the forced swimming test. Data showed that rats exposed to one week of constant light exhibited increased number of quadrants crossed in the open field. No change on anxiety-like behaviors (time and quadrants crossed in the center of apparatus) was observed in the open field test. One week of constant dark increased the time of immobility behavior in the forced swimming test relative to control 12/12h light/dark treatment. Therefore, one week of continuous light induced locomotor hyperactivity and one week of continuous dark induced depressive-like behaviors following reestablishment of normal 12/12h light/dark cycle. Such data demonstrate the importance of light/dark environmental rhythm on mood changes and the significance of light/dark cycle control on behavioral studies. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-17 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufu.br/index.php/biosciencejournal/article/view/28247 10.14393/BJ-v31n6a2015-28247 |
url |
https://seer.ufu.br/index.php/biosciencejournal/article/view/28247 |
identifier_str_mv |
10.14393/BJ-v31n6a2015-28247 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://seer.ufu.br/index.php/biosciencejournal/article/view/28247/17403 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.coverage.none.fl_str_mv |
Brazil; Contemporary |
dc.publisher.none.fl_str_mv |
EDUFU |
publisher.none.fl_str_mv |
EDUFU |
dc.source.none.fl_str_mv |
Bioscience Journal ; Vol. 31 No. 6 (2015): Nov./Dec.; 1837-184 Bioscience Journal ; v. 31 n. 6 (2015): Nov./Dec.; 1837-184 1981-3163 reponame:Bioscience journal (Online) instname:Universidade Federal de Uberlândia (UFU) instacron:UFU |
instname_str |
Universidade Federal de Uberlândia (UFU) |
instacron_str |
UFU |
institution |
UFU |
reponame_str |
Bioscience journal (Online) |
collection |
Bioscience journal (Online) |
repository.name.fl_str_mv |
Bioscience journal (Online) - Universidade Federal de Uberlândia (UFU) |
repository.mail.fl_str_mv |
biosciencej@ufu.br|| |
_version_ |
1797069075392757760 |