"Omics" studies on carbon nanoparticles effects

Detalhes bibliográficos
Autor(a) principal: Garcia Hernandez, Liudy
Data de Publicação: 2015
Outros Autores: Espindola, Foued Salmen, García, Luis Felipe Desdin
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Bioscience journal (Online)
Texto Completo: https://seer.ufu.br/index.php/biosciencejournal/article/view/28473
Resumo: Nanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide powerful tools that are sensitive and complementary for the study of molecular toxicology and for biomedical applications of nanomaterials. Specifically, proteomics could elucidate mechanisms of action and contribute to studies on how nanomaterials affect protein expression in tissues and organs, metabolic pathways, signal transduction mechanisms and target molecules. The objective of this review is to present a small approach about "omics" technologies applied to the study of the effect of carbon nanomaterials in the cell.
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spelling "Omics" studies on carbon nanoparticles effects Health SciencesNanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide powerful tools that are sensitive and complementary for the study of molecular toxicology and for biomedical applications of nanomaterials. Specifically, proteomics could elucidate mechanisms of action and contribute to studies on how nanomaterials affect protein expression in tissues and organs, metabolic pathways, signal transduction mechanisms and target molecules. The objective of this review is to present a small approach about "omics" technologies applied to the study of the effect of carbon nanomaterials in the cell.EDUFU2015-06-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.ufu.br/index.php/biosciencejournal/article/view/2847310.14393/BJ-v31n4a2015-28473Bioscience Journal ; Vol. 31 No. 4 (2015): July/Aug.; 1260-1269Bioscience Journal ; v. 31 n. 4 (2015): July/Aug.; 1260-12691981-3163reponame:Bioscience journal (Online)instname:Universidade Federal de Uberlândia (UFU)instacron:UFUenghttps://seer.ufu.br/index.php/biosciencejournal/article/view/28473/16751Brazil; ContemporaryCopyright (c) 2015 Liudy Garcia Hernandez, Foued Salmen Espindola, Luis Felipe Desdin Garcíahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGarcia Hernandez, LiudyEspindola, Foued SalmenGarcía, Luis Felipe Desdin2022-05-22T20:11:18Zoai:ojs.www.seer.ufu.br:article/28473Revistahttps://seer.ufu.br/index.php/biosciencejournalPUBhttps://seer.ufu.br/index.php/biosciencejournal/oaibiosciencej@ufu.br||1981-31631516-3725opendoar:2022-05-22T20:11:18Bioscience journal (Online) - Universidade Federal de Uberlândia (UFU)false
dc.title.none.fl_str_mv "Omics" studies on carbon nanoparticles effects
title "Omics" studies on carbon nanoparticles effects
spellingShingle "Omics" studies on carbon nanoparticles effects
Garcia Hernandez, Liudy
Health Sciences
title_short "Omics" studies on carbon nanoparticles effects
title_full "Omics" studies on carbon nanoparticles effects
title_fullStr "Omics" studies on carbon nanoparticles effects
title_full_unstemmed "Omics" studies on carbon nanoparticles effects
title_sort "Omics" studies on carbon nanoparticles effects
author Garcia Hernandez, Liudy
author_facet Garcia Hernandez, Liudy
Espindola, Foued Salmen
García, Luis Felipe Desdin
author_role author
author2 Espindola, Foued Salmen
García, Luis Felipe Desdin
author2_role author
author
dc.contributor.author.fl_str_mv Garcia Hernandez, Liudy
Espindola, Foued Salmen
García, Luis Felipe Desdin
dc.subject.por.fl_str_mv Health Sciences
topic Health Sciences
description Nanoparticles are being explored for biomedical applications in diagnostics and therapeutics. However, biocompatibility, toxicity and cellular entry ability are critical factors that will determine the utility of nanoparticles in clinical applications. "Omics" technologies can provide powerful tools that are sensitive and complementary for the study of molecular toxicology and for biomedical applications of nanomaterials. Specifically, proteomics could elucidate mechanisms of action and contribute to studies on how nanomaterials affect protein expression in tissues and organs, metabolic pathways, signal transduction mechanisms and target molecules. The objective of this review is to present a small approach about "omics" technologies applied to the study of the effect of carbon nanomaterials in the cell.
publishDate 2015
dc.date.none.fl_str_mv 2015-06-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufu.br/index.php/biosciencejournal/article/view/28473
10.14393/BJ-v31n4a2015-28473
url https://seer.ufu.br/index.php/biosciencejournal/article/view/28473
identifier_str_mv 10.14393/BJ-v31n4a2015-28473
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://seer.ufu.br/index.php/biosciencejournal/article/view/28473/16751
dc.rights.driver.fl_str_mv Copyright (c) 2015 Liudy Garcia Hernandez, Foued Salmen Espindola, Luis Felipe Desdin García
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2015 Liudy Garcia Hernandez, Foued Salmen Espindola, Luis Felipe Desdin García
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Brazil; Contemporary
dc.publisher.none.fl_str_mv EDUFU
publisher.none.fl_str_mv EDUFU
dc.source.none.fl_str_mv Bioscience Journal ; Vol. 31 No. 4 (2015): July/Aug.; 1260-1269
Bioscience Journal ; v. 31 n. 4 (2015): July/Aug.; 1260-1269
1981-3163
reponame:Bioscience journal (Online)
instname:Universidade Federal de Uberlândia (UFU)
instacron:UFU
instname_str Universidade Federal de Uberlândia (UFU)
instacron_str UFU
institution UFU
reponame_str Bioscience journal (Online)
collection Bioscience journal (Online)
repository.name.fl_str_mv Bioscience journal (Online) - Universidade Federal de Uberlândia (UFU)
repository.mail.fl_str_mv biosciencej@ufu.br||
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