Análise vibracional e espacial de óxido de grafeno e DNTPs
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFU |
Texto Completo: | https://repositorio.ufu.br/handle/123456789/29651 http://doi.org/10.14393/ufu.di.2020.300 |
Resumo: | This work is about the study of the interaction between oxidized graphene (GO) and dNTPs (Deoxynucleotides triphosphate) - dATP, dCTP, dGTP and dTTP; two materials widely studied and applied in the field of nanomedicine. The materials were characterized using Raman spectroscopy and the surface scanning method called AFM (“atomic force microscopy”), individually and in a composite. From the oxidized graphene, we were able to analyze its characteristic bands through its vibrational spectrum and the profiles of its leaves through the surface images. As for the constituent bases of DNA, an assignment of the vibrational modes corresponding to each of its groups was carried out. The individual characterization of the materials was made for comparison with the composites in order to detect changes caused by the interaction of the materials. In this work, we were able to infer after analyzing and comparing spectra and surface profiles of composites, that there is a different interaction between the bases classified as purines (dATP and dGTP) and pyrimidines (dCTP and dTTP) with oxidized graphene. |
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Análise vibracional e espacial de óxido de grafeno e DNTPsVibrational and spatial analysis of graphene oxide and DNTPsRamanGrafenoDNTPGrapheneFísicaCNPQ::CIENCIAS EXATAS E DA TERRA::FISICA::FISICA DA MATERIA CONDENSADAThis work is about the study of the interaction between oxidized graphene (GO) and dNTPs (Deoxynucleotides triphosphate) - dATP, dCTP, dGTP and dTTP; two materials widely studied and applied in the field of nanomedicine. The materials were characterized using Raman spectroscopy and the surface scanning method called AFM (“atomic force microscopy”), individually and in a composite. From the oxidized graphene, we were able to analyze its characteristic bands through its vibrational spectrum and the profiles of its leaves through the surface images. As for the constituent bases of DNA, an assignment of the vibrational modes corresponding to each of its groups was carried out. The individual characterization of the materials was made for comparison with the composites in order to detect changes caused by the interaction of the materials. In this work, we were able to infer after analyzing and comparing spectra and surface profiles of composites, that there is a different interaction between the bases classified as purines (dATP and dGTP) and pyrimidines (dCTP and dTTP) with oxidized graphene.CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorDissertação (Mestrado)Este trabalho trata do estudo da interação entre o grafeno oxidado (GO) e dNTPs (Desoxinucleotídeos trifosfato)- dATP, dCTP, dGTP e dTTP; dois materiais amplamente estudados e aplicáveis na área da nanomedicina. Os materiais foram caracterizados através de espectroscopia Raman e do método de escaneamento de superfície chamado AFM (“atomic force microscopy”), de forma individual e em compósito. Do grafeno oxidado, pudemos analisar suas bandas características através de seu espectro vibracional e os perfis de suas folhas através das imagens de superfície. Quanto às bases constituintes do DNA, foi realizada uma atribuição dos modos vibracionais correspondentes a cada um de seus grupamentos. A caracterização individual dos materiais foi feita para a comparação com os compósitos de modo a detectar alterações provocadas pela interação dos materiais. Neste trabalho, pudemos inferir após a análise e comparação de espectros e perfis de superfície dos compósitos, que há uma diferente interação entre as bases classificadas como purinas (dATP e dGTP) e pirimidinas (dCTP e dTTP) com o grafeno oxidado.Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em FísicaSilva, Raigna Augusta dahttp://lattes.cnpq.br/8550035837459093Marletta, AlexandreFurtado, Clascidia AparecidaZaramella, Pedro Henrique Dondori2020-08-10T22:15:27Z2020-08-10T22:15:27Z2020-02-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfZARAMELLA, Pedro Henrique Dondori. Análise vibracional e espacial de óxido de grafeno e DNTPs. 2020. 136f. Dissertação (Mestrado em Física) - Universidade Federal de Uberlândia, Uberlândia, 2020. DOI http://doi.org/10.14393/ufu.di.2020.300https://repositorio.ufu.br/handle/123456789/29651http://doi.org/10.14393/ufu.di.2020.300porhttp://creativecommons.org/licenses/by-nc-nd/3.0/us/info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFUinstname:Universidade Federal de Uberlândia (UFU)instacron:UFU2021-10-20T18:20:48Zoai:repositorio.ufu.br:123456789/29651Repositório InstitucionalONGhttp://repositorio.ufu.br/oai/requestdiinf@dirbi.ufu.bropendoar:2021-10-20T18:20:48Repositório Institucional da UFU - Universidade Federal de Uberlândia (UFU)false |
dc.title.none.fl_str_mv |
Análise vibracional e espacial de óxido de grafeno e DNTPs Vibrational and spatial analysis of graphene oxide and DNTPs |
title |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
spellingShingle |
Análise vibracional e espacial de óxido de grafeno e DNTPs Zaramella, Pedro Henrique Dondori Raman Grafeno DNTP Graphene Física CNPQ::CIENCIAS EXATAS E DA TERRA::FISICA::FISICA DA MATERIA CONDENSADA |
title_short |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
title_full |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
title_fullStr |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
title_full_unstemmed |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
title_sort |
Análise vibracional e espacial de óxido de grafeno e DNTPs |
author |
Zaramella, Pedro Henrique Dondori |
author_facet |
Zaramella, Pedro Henrique Dondori |
author_role |
author |
dc.contributor.none.fl_str_mv |
Silva, Raigna Augusta da http://lattes.cnpq.br/8550035837459093 Marletta, Alexandre Furtado, Clascidia Aparecida |
dc.contributor.author.fl_str_mv |
Zaramella, Pedro Henrique Dondori |
dc.subject.por.fl_str_mv |
Raman Grafeno DNTP Graphene Física CNPQ::CIENCIAS EXATAS E DA TERRA::FISICA::FISICA DA MATERIA CONDENSADA |
topic |
Raman Grafeno DNTP Graphene Física CNPQ::CIENCIAS EXATAS E DA TERRA::FISICA::FISICA DA MATERIA CONDENSADA |
description |
This work is about the study of the interaction between oxidized graphene (GO) and dNTPs (Deoxynucleotides triphosphate) - dATP, dCTP, dGTP and dTTP; two materials widely studied and applied in the field of nanomedicine. The materials were characterized using Raman spectroscopy and the surface scanning method called AFM (“atomic force microscopy”), individually and in a composite. From the oxidized graphene, we were able to analyze its characteristic bands through its vibrational spectrum and the profiles of its leaves through the surface images. As for the constituent bases of DNA, an assignment of the vibrational modes corresponding to each of its groups was carried out. The individual characterization of the materials was made for comparison with the composites in order to detect changes caused by the interaction of the materials. In this work, we were able to infer after analyzing and comparing spectra and surface profiles of composites, that there is a different interaction between the bases classified as purines (dATP and dGTP) and pyrimidines (dCTP and dTTP) with oxidized graphene. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-10T22:15:27Z 2020-08-10T22:15:27Z 2020-02-20 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
ZARAMELLA, Pedro Henrique Dondori. Análise vibracional e espacial de óxido de grafeno e DNTPs. 2020. 136f. Dissertação (Mestrado em Física) - Universidade Federal de Uberlândia, Uberlândia, 2020. DOI http://doi.org/10.14393/ufu.di.2020.300 https://repositorio.ufu.br/handle/123456789/29651 http://doi.org/10.14393/ufu.di.2020.300 |
identifier_str_mv |
ZARAMELLA, Pedro Henrique Dondori. Análise vibracional e espacial de óxido de grafeno e DNTPs. 2020. 136f. Dissertação (Mestrado em Física) - Universidade Federal de Uberlândia, Uberlândia, 2020. DOI http://doi.org/10.14393/ufu.di.2020.300 |
url |
https://repositorio.ufu.br/handle/123456789/29651 http://doi.org/10.14393/ufu.di.2020.300 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/3.0/us/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/3.0/us/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Uberlândia Brasil Programa de Pós-graduação em Física |
publisher.none.fl_str_mv |
Universidade Federal de Uberlândia Brasil Programa de Pós-graduação em Física |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFU instname:Universidade Federal de Uberlândia (UFU) instacron:UFU |
instname_str |
Universidade Federal de Uberlândia (UFU) |
instacron_str |
UFU |
institution |
UFU |
reponame_str |
Repositório Institucional da UFU |
collection |
Repositório Institucional da UFU |
repository.name.fl_str_mv |
Repositório Institucional da UFU - Universidade Federal de Uberlândia (UFU) |
repository.mail.fl_str_mv |
diinf@dirbi.ufu.br |
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1805569662334795776 |