Modificações dopplervelocimétricas da artéria oftálmica em pacientes com diabetes mellitus pré-gestacional

• Autor(a) principal: Damian, Nicholas Godoy Canazza
• Data de Publicação: 2012
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UFU
• Texto Completo: https://repositorio.ufu.br/handle/123456789/12734; https://doi.org/10.14393/ufu.di.2012.196
• topic: Diabetes mellitus; Artéria oftálmica; Dopplervelocimetria; Gestação; Vasculopatia; Diabetes; Mulheres grávidas; Ophthalmic artery; Doppler; Pregnancy; CNPQ::CIENCIAS DA SAUDE

Objective: The purpose of this paper is to analyze the pre-gestational diabetes can modify the defaults maternal ophthalmic artery Doppler velocimetry. Methods: This prospective observational study that examined the ophthalmic artery Doppler 30 pregnant women with pre-gestational diabetes according to the criteria of the American Diabetes Association (ADA) and compared with data from a control group of 40 normal pregnant women. Inclusion criteria were pregnant women above 18 years with a diagnosis of diabetes mellitus type I, II, or secondary, with a gestational age greater than or equal to 20 weeks. We excluded patients with heart disease, and hypertensive smokers. All patients underwent obstetrical ultrasound examination, focusing on Doppler examination of the ophthalmic artery. The following variables were measured in the ophthalmic artery, resistance index (RI), pulsatility index (PI), peak velocity ratio (RPV), peak systolic velocity (PSV) and end diastolic velocity (EDV). Statistical analysis was performed calculating the average, median and standard deviation (SD) of variables and applying Student\'s t test and Mann-Whitney test as normality of the sample. The significance level was 95%. Results: The diabetic women had a mean age of 28 years (SD 8.5) and mean gestational age 30 weeks (SD 2.8). The average or median and SD of the indexes of the study group were: RI = 0.75, PI = 1.83 (SD 0.34); RPV = 0.53 (SD 0.01), PSV = 31.92; VDF = 7.89. When comparing the mean between the study group and normal group of patients showed an increase of PSV and EDV in the diabetic group compared to the normal group, with significant results (p = 0.020 and p = 0.005 respectively). The other Doppler indices did not differ significantly between the two groups. Conclusion: In this study it was observed that the ophthalmic artery Doppler signals identified orbital hyperperfusion in diabetic pregnant women, by high values of peak systolic velocity and end diastolic velocity in relation to pregnant women.