Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits

Detalhes bibliográficos
Autor(a) principal: Pontes,Kelly Cristine de Sousa
Data de Publicação: 2012
Outros Autores: Borges,Andréa Pacheco Batista, Eleotério,Renato Barros, Reis,Emily Correna Carlo, Duarte,Tatiana Schmitz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista Ceres
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2012000300004
Resumo: The aim of this study was to evaluate the effects of canine amniotic membrane, previously preserved in glycerin, used as a patch on the repair of experimentally-made superficial corneal ulcers and to compare corneal epithelization between the treated and non-treated groups. Xenogeneic amniotic membranes were collected aseptically and preserved in 99% glycerin at room temperature. Each animal was anesthetized and submitted to superficial corneal keratectomy of the left eye. The treated group received a fragment of canine amniotic membrane as a patch, while the control group had no treatment. The treated group showed blepharospasm, ocular discharge and conjunctival congestion. The membrane accelerated corneal repair in the beginning of the process, however, it delayed its conclusion (p<0.05). Treated eyes showed greater vessel formation and decreased corneal transparency (p<0.05). The stroma of the control group was thicker than that of the treated group (p<0.05). We suggest that amniotic membrane used in this manner can be applied as a therapy for superficial corneal ulcers in the beginning phases of the repair process.
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spelling Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbitscorneasurgeryveterinary ophthalmologybiomaterialsThe aim of this study was to evaluate the effects of canine amniotic membrane, previously preserved in glycerin, used as a patch on the repair of experimentally-made superficial corneal ulcers and to compare corneal epithelization between the treated and non-treated groups. Xenogeneic amniotic membranes were collected aseptically and preserved in 99% glycerin at room temperature. Each animal was anesthetized and submitted to superficial corneal keratectomy of the left eye. The treated group received a fragment of canine amniotic membrane as a patch, while the control group had no treatment. The treated group showed blepharospasm, ocular discharge and conjunctival congestion. The membrane accelerated corneal repair in the beginning of the process, however, it delayed its conclusion (p<0.05). Treated eyes showed greater vessel formation and decreased corneal transparency (p<0.05). The stroma of the control group was thicker than that of the treated group (p<0.05). We suggest that amniotic membrane used in this manner can be applied as a therapy for superficial corneal ulcers in the beginning phases of the repair process.Universidade Federal de Viçosa2012-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2012000300004Revista Ceres v.59 n.3 2012reponame:Revista Ceresinstname:Universidade Federal de Viçosa (UFV)instacron:UFV10.1590/S0034-737X2012000300004info:eu-repo/semantics/openAccessPontes,Kelly Cristine de SousaBorges,Andréa Pacheco BatistaEleotério,Renato BarrosReis,Emily Correna CarloDuarte,Tatiana Schmitzeng2015-07-02T00:00:00ZRevista
dc.title.none.fl_str_mv Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
title Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
spellingShingle Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
Pontes,Kelly Cristine de Sousa
cornea
surgery
veterinary ophthalmology
biomaterials
title_short Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
title_full Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
title_fullStr Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
title_full_unstemmed Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
title_sort Preserved xenogenic amniotic membrane as a patch on the repair of superficial corneal ulcers in rabbits
author Pontes,Kelly Cristine de Sousa
author_facet Pontes,Kelly Cristine de Sousa
Borges,Andréa Pacheco Batista
Eleotério,Renato Barros
Reis,Emily Correna Carlo
Duarte,Tatiana Schmitz
author_role author
author2 Borges,Andréa Pacheco Batista
Eleotério,Renato Barros
Reis,Emily Correna Carlo
Duarte,Tatiana Schmitz
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pontes,Kelly Cristine de Sousa
Borges,Andréa Pacheco Batista
Eleotério,Renato Barros
Reis,Emily Correna Carlo
Duarte,Tatiana Schmitz
dc.subject.por.fl_str_mv cornea
surgery
veterinary ophthalmology
biomaterials
topic cornea
surgery
veterinary ophthalmology
biomaterials
dc.description.none.fl_txt_mv The aim of this study was to evaluate the effects of canine amniotic membrane, previously preserved in glycerin, used as a patch on the repair of experimentally-made superficial corneal ulcers and to compare corneal epithelization between the treated and non-treated groups. Xenogeneic amniotic membranes were collected aseptically and preserved in 99% glycerin at room temperature. Each animal was anesthetized and submitted to superficial corneal keratectomy of the left eye. The treated group received a fragment of canine amniotic membrane as a patch, while the control group had no treatment. The treated group showed blepharospasm, ocular discharge and conjunctival congestion. The membrane accelerated corneal repair in the beginning of the process, however, it delayed its conclusion (p<0.05). Treated eyes showed greater vessel formation and decreased corneal transparency (p<0.05). The stroma of the control group was thicker than that of the treated group (p<0.05). We suggest that amniotic membrane used in this manner can be applied as a therapy for superficial corneal ulcers in the beginning phases of the repair process.
description The aim of this study was to evaluate the effects of canine amniotic membrane, previously preserved in glycerin, used as a patch on the repair of experimentally-made superficial corneal ulcers and to compare corneal epithelization between the treated and non-treated groups. Xenogeneic amniotic membranes were collected aseptically and preserved in 99% glycerin at room temperature. Each animal was anesthetized and submitted to superficial corneal keratectomy of the left eye. The treated group received a fragment of canine amniotic membrane as a patch, while the control group had no treatment. The treated group showed blepharospasm, ocular discharge and conjunctival congestion. The membrane accelerated corneal repair in the beginning of the process, however, it delayed its conclusion (p<0.05). Treated eyes showed greater vessel formation and decreased corneal transparency (p<0.05). The stroma of the control group was thicker than that of the treated group (p<0.05). We suggest that amniotic membrane used in this manner can be applied as a therapy for superficial corneal ulcers in the beginning phases of the repair process.
publishDate 2012
dc.date.none.fl_str_mv 2012-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2012000300004
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2012000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0034-737X2012000300004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Federal de Viçosa
publisher.none.fl_str_mv Universidade Federal de Viçosa
dc.source.none.fl_str_mv Revista Ceres v.59 n.3 2012
reponame:Revista Ceres
instname:Universidade Federal de Viçosa (UFV)
instacron:UFV
instname_str Universidade Federal de Viçosa (UFV)
instacron_str UFV
institution UFV
reponame_str Revista Ceres
collection Revista Ceres
repository.name.fl_str_mv
repository.mail.fl_str_mv
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