Detecção de locos de características quantitativas com efeito da origem parental dos alelos nos cromossomos 1, 2 e 4 de suínos

• Autor(a) principal: Silva Filho, Miguel Inácio da
• Data de Publicação: 2010
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: LOCUS Repositório Institucional da UFV
• Texto Completo: http://locus.ufv.br/handle/123456789/4726
• topic: Suínos; População F2; QTL; Imprinting; Pigs; F2 Population; QTL; Imprinting; CNPQ::CIENCIAS AGRARIAS::ZOOTECNIA::GENETICA E MELHORAMENTO DOS ANIMAIS DOMESTICOS

Data from an F2 swine population, consisting of 600 animals derived from crosses between Piau sires and Commercial dams were used in order to detect QTL with parent-of-origin effects. Phenotypic data on performance, carcass, internal organs, viscera, carcass cuts and meat quality traits were collected in the F2 animals. The population was genotyped for 16 microsatellite loci covering the chromosomes 1, 2 and 144. Based on the genotypes a specific linkage map was constructed for this population. Association analyses were performed using interval mapping by regression for QTL detection. A decision tree for identifying QTL with parent-of-origin effects based on tests against the Mendelian mode of expression was used. Twenty three QTL were detected using the Mendelian model of analysis, three on the chromosome one, five on chromosome two and 15 on chromosome four. It was also detected 12 QTL with parentof-origin effects. Six of these QTL were identified on chromosome one, where three were paternally expressed and three were maternally expressed. Three QTL were detected on chromosome two, where one was paternally expressed and the other two were maternally expressed. The remaining three QTL were identified on chromosome four, all of them were paternally expressed. None of the QTL with parent-of-origin effects was detected by the Mendelian model. The results generated in this study may contribute to a better understanding of the genetic mechanisms involved in the control of quantitative traits.