Freqüência e distribuição de Helicobacter ssp. na mucosa gástrica de cães

• Autor(a) principal: Vieira, Fernanda de Toledo
• Data de Publicação: 2004
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: LOCUS Repositório Institucional da UFV
• Texto Completo: http://locus.ufv.br/handle/123456789/4995
• topic: Cão; Estômago; Úlceras; Helicobacter pylori; Dogs; Stomach; Ulcer; Helicobacter pylori; CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::PATOLOGIA ANIMAL

The discovery of Helicobacter pylori in human beings and its relation with gastritis, peptic ulcer and gastric neoplasia, has renewed the interest on the establishment of the incidence and on the clinical meaning of this bacteria in pets, specifically in dogs. There are several researches that indicate the presence of Helicobacter ssp in dogs, even though the relation of these bacteria with gastric alterations in dogs has not been clarified yet. The aim of this dissertation was to evaluate the presence of Helicobacter ssp in dogs, to analyse the macro and microscopic findings, determine the correlation between the presence of the bacteria with alterations in the gastric mucosa, and of these with the dogs age, and additionally to investigate the correlation of the positiveness of the urease test with the presence of the bacteria. During the necropsy of 60 dogs, samples from cardia, fundus, body, and pylorus regions were collected from the dogs stomach for conducting the urease test and histopathologic examination. The urease test was positive in 95,12% of the animals. The histopathologic examination using Carbol-Fucsina coloration revealed Helicobacter ssp in 96,66% of the animals. The most frequent observed alteration in preparations colored by HE were infiltrated with inflammatory cells, predominantly mononuclear, lymphoid nodules hyperplasia and hiperemy. Correlation between the urease test and the histopathology for the diagnostic of Helicobacter ssp in dogs was found. Age was not found correlated with infection by Helicobacter ssp. It was not found any correlation between inflamatory alterations, in the presence of the bacteria, with the age of the animals. The fundus and body stomach regions presented more positive results in the urease test and the body and pylorus regions presented more positive results in the histopathologic examination. There was correlation between the number of Helicobacter ssp, the number of inflamatory cells and lymphoid nodules in those regions. The high percentage of dogs infected by Helicobacter ssp and the variation in the patogenicity among the species indicate the necessity of further investigation for the identification of species more pathogenic and mechanisms of patogenicity in dogs. Besides, due to the zoonotic potential, further research should be done on the helicobacterias.