A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | LOCUS Repositório Institucional da UFV |
Texto Completo: | https://doi.org/10.1016/j.pscychresns.2015.05.009 http://www.locus.ufv.br/handle/123456789/19310 |
Resumo: | Facial emotion recognition (FER) is one of the many cognitive deficits reported in bipolar disorder (BD) patients. The aim of this study was to investigate neuroanatomical correlates of FER impairments in BD type I (BD-I). Participants comprised 21 euthymic BD-I patients without Axis I DSM IV-TR comorbidities and 21 healthy controls who were assessed using magnetic resonance imaging and the Penn Emotion Recognition Test (ER40). Preprocessing of images used DARTEL (diffeomorphic anatomical registration through exponentiated Lie algebra) for optimized voxel-based morphometry in SPM8. Compared with healthy subjects, BD-I patients performed poorly in on the ER40 and had reduced gray matter volume (GMV) in the left orbitofrontal cortex, superior portion of the temporal pole and insula. In the BD-I group, the statistical maps indicated a direct correlation between FER on the ER40 and right middle cingulate gyrus GMV. Our findings are consistent with the previous studies regarding the overlap of multiple brain networks of social cognition and BD neurobiology, particularly components of the anterior-limbic neural network. |
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Neves, Maila de Castro L.Albuquerque, Maicon RodriguesMalloy-Diniz, LeandroNicolato, RodrigoNeves, Fernando SilvaSouza-Duran, Fábio Luis deBusatto, GeraldoCorrêa, Humberto2018-05-03T14:14:34Z2018-05-03T14:14:34Z2015-05-2709254927https://doi.org/10.1016/j.pscychresns.2015.05.009http://www.locus.ufv.br/handle/123456789/19310Facial emotion recognition (FER) is one of the many cognitive deficits reported in bipolar disorder (BD) patients. The aim of this study was to investigate neuroanatomical correlates of FER impairments in BD type I (BD-I). Participants comprised 21 euthymic BD-I patients without Axis I DSM IV-TR comorbidities and 21 healthy controls who were assessed using magnetic resonance imaging and the Penn Emotion Recognition Test (ER40). Preprocessing of images used DARTEL (diffeomorphic anatomical registration through exponentiated Lie algebra) for optimized voxel-based morphometry in SPM8. Compared with healthy subjects, BD-I patients performed poorly in on the ER40 and had reduced gray matter volume (GMV) in the left orbitofrontal cortex, superior portion of the temporal pole and insula. In the BD-I group, the statistical maps indicated a direct correlation between FER on the ER40 and right middle cingulate gyrus GMV. Our findings are consistent with the previous studies regarding the overlap of multiple brain networks of social cognition and BD neurobiology, particularly components of the anterior-limbic neural network.engPsychiatry Research: Neuroimagingv. 233, Issue 2, p. 158-164, August 2015Elsevier Ireland Ltd.info:eu-repo/semantics/openAccessBipolar disorderSocial cognitionFacial emotion recognitionVoxel-based morphometry (VBM)A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorderinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfreponame:LOCUS Repositório Institucional da UFVinstname:Universidade Federal de Viçosa (UFV)instacron:UFVORIGINALartigo.pdfartigo.pdfTexto completoapplication/pdf846608https://locus.ufv.br//bitstream/123456789/19310/1/artigo.pdfb69e4ab3d2f428a5d375b270d58a675cMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://locus.ufv.br//bitstream/123456789/19310/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILartigo.pdf.jpgartigo.pdf.jpgIM Thumbnailimage/jpeg6282https://locus.ufv.br//bitstream/123456789/19310/3/artigo.pdf.jpg066fb32896328c9596ec30ba6a0501efMD53123456789/193102018-05-03 23:00:38.594oai:locus.ufv.br:123456789/19310Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.locus.ufv.br/oai/requestfabiojreis@ufv.bropendoar:21452018-05-04T02:00:38LOCUS Repositório Institucional da UFV - Universidade Federal de Viçosa (UFV)false |
dc.title.en.fl_str_mv |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
title |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
spellingShingle |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder Neves, Maila de Castro L. Bipolar disorder Social cognition Facial emotion recognition Voxel-based morphometry (VBM) |
title_short |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
title_full |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
title_fullStr |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
title_full_unstemmed |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
title_sort |
A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder |
author |
Neves, Maila de Castro L. |
author_facet |
Neves, Maila de Castro L. Albuquerque, Maicon Rodrigues Malloy-Diniz, Leandro Nicolato, Rodrigo Neves, Fernando Silva Souza-Duran, Fábio Luis de Busatto, Geraldo Corrêa, Humberto |
author_role |
author |
author2 |
Albuquerque, Maicon Rodrigues Malloy-Diniz, Leandro Nicolato, Rodrigo Neves, Fernando Silva Souza-Duran, Fábio Luis de Busatto, Geraldo Corrêa, Humberto |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Neves, Maila de Castro L. Albuquerque, Maicon Rodrigues Malloy-Diniz, Leandro Nicolato, Rodrigo Neves, Fernando Silva Souza-Duran, Fábio Luis de Busatto, Geraldo Corrêa, Humberto |
dc.subject.pt-BR.fl_str_mv |
Bipolar disorder Social cognition Facial emotion recognition Voxel-based morphometry (VBM) |
topic |
Bipolar disorder Social cognition Facial emotion recognition Voxel-based morphometry (VBM) |
description |
Facial emotion recognition (FER) is one of the many cognitive deficits reported in bipolar disorder (BD) patients. The aim of this study was to investigate neuroanatomical correlates of FER impairments in BD type I (BD-I). Participants comprised 21 euthymic BD-I patients without Axis I DSM IV-TR comorbidities and 21 healthy controls who were assessed using magnetic resonance imaging and the Penn Emotion Recognition Test (ER40). Preprocessing of images used DARTEL (diffeomorphic anatomical registration through exponentiated Lie algebra) for optimized voxel-based morphometry in SPM8. Compared with healthy subjects, BD-I patients performed poorly in on the ER40 and had reduced gray matter volume (GMV) in the left orbitofrontal cortex, superior portion of the temporal pole and insula. In the BD-I group, the statistical maps indicated a direct correlation between FER on the ER40 and right middle cingulate gyrus GMV. Our findings are consistent with the previous studies regarding the overlap of multiple brain networks of social cognition and BD neurobiology, particularly components of the anterior-limbic neural network. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-05-27 |
dc.date.accessioned.fl_str_mv |
2018-05-03T14:14:34Z |
dc.date.available.fl_str_mv |
2018-05-03T14:14:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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dc.identifier.uri.fl_str_mv |
https://doi.org/10.1016/j.pscychresns.2015.05.009 http://www.locus.ufv.br/handle/123456789/19310 |
dc.identifier.issn.none.fl_str_mv |
09254927 |
identifier_str_mv |
09254927 |
url |
https://doi.org/10.1016/j.pscychresns.2015.05.009 http://www.locus.ufv.br/handle/123456789/19310 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofseries.pt-BR.fl_str_mv |
v. 233, Issue 2, p. 158-164, August 2015 |
dc.rights.driver.fl_str_mv |
Elsevier Ireland Ltd. info:eu-repo/semantics/openAccess |
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Elsevier Ireland Ltd. |
eu_rights_str_mv |
openAccess |
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dc.publisher.none.fl_str_mv |
Psychiatry Research: Neuroimaging |
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Psychiatry Research: Neuroimaging |
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