Efeitos da aplicação do laser a diodo de arseneto de gálio (As-Ga) na osteoartrite experimental em coelhos

• Autor(a) principal: Lobato, Danielle Andreazzi
• Data de Publicação: 2003
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: LOCUS Repositório Institucional da UFV
• Texto Completo: http://locus.ufv.br/handle/123456789/5200
• topic: Laserterapia; Osteoartrite; Doença degenerativa; Lasertherapy; Ostheoarthritis; Degenerative disease; CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL

The aim of this study was to evaluate the effects of gallium arsenite (Ga-As) diode laser application on rabbits knees with ostheoarthritis induced by intrarticular injection of carrageenan. Clinical evaluation in vivo showed that there was reduction in inflammatory signs and pain, with treated animals presenting a better performance and greater amplitude of movements, if compared with untreated animals. The degenerative processes resulting from the administration of carrageenan were evidenced in both groups by post-mortem macroscopic and microscopic assessment in both treated and control groups, which allowed inferring that laser diminished the presence of chemical mediators, reducing the inflammatory response and local lesions, including the degradation of glycosaminoglycans. Histological analysis of the synovial membrane revealed the presence of inflammatory cells distributed diffusely or in foci, the intensity of which was higher in control groups. It was concluded therefore that the rate of progression of ostheoarthritis was slowed down by lasertherapy.