Relação da doença periodontal com espessura da parede íntima-média da artéria carótida

Detalhes bibliográficos
Autor(a) principal: Castagna, Lisiane
Data de Publicação: 2009
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UNIGRANRIO
Texto Completo: http://localhost:8080/tede/handle/tede/81
Resumo: Chronic infections and inflammation are considered risk factors for the development of cardiovascular diseases. Recent studies indicate that severe periodontitis may increase proinflammatory cytokines and markers of inflammation associated with increased risk of coronary disease and stroke. The intima-media layer thickness of the carotid artery is considered a risk marker for cardiovascular diseases. The purpose of this study was to investigate the relationship between periodontal disease and the myo-intimal thickening of carotid arteries. Noninvasive measurements of the intima-media of the common, internal and external carotid artery bilaterally were made in 217 subjects with mean age of 62.28 (SD:10.37). Tooth loss and clinical parameters of periodontal disease such as pocket depth and attachment level obtained from six sites of every tooth were recorded. Also, an interview was conducted about medical and dental history. The results indicated chronic generalized periodontitis was more prevalent in individuals with plaque (61,36%) and subclinical atherosclerosis (21,59%) than less extensive periodontal disease (P=0,0001). The severity of periodontal disease was also prevalent in the stenotic group (58,82%) compared to the mild/moderate periodontitis group (P=0,0242). Additionally, fewer teeth (P=0.0007) were also more prevalent in the group with stenosis. Thus we can conclude that this study found the association between partial stenosis in the intima-media wall of carotidio system (atheromatous plaques) and subclinical atherosclerosis and the extent and severity of chronic generalized periodontal disease and numbers of teeth.
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spelling Tinoco, Eduardo Muniz BarrettoSilva, Denise Gomes daFalabella, Marcio Eduardo VieiraFischer, Ricardo GuimarãesCastagna, Lisiane2016-10-19T17:24:00Z2009-09-09Castagna, Lisiane. Relação da doença periodontal com espessura da parede íntima-média da artéria carótida. 2009. [72] f. Dissertação (mestrado em Odontologia) - Universidade do Grande Rio “Prof. José de Souza Herdy”, Duque de Caxias.http://localhost:8080/tede/handle/tede/81Chronic infections and inflammation are considered risk factors for the development of cardiovascular diseases. Recent studies indicate that severe periodontitis may increase proinflammatory cytokines and markers of inflammation associated with increased risk of coronary disease and stroke. The intima-media layer thickness of the carotid artery is considered a risk marker for cardiovascular diseases. The purpose of this study was to investigate the relationship between periodontal disease and the myo-intimal thickening of carotid arteries. Noninvasive measurements of the intima-media of the common, internal and external carotid artery bilaterally were made in 217 subjects with mean age of 62.28 (SD:10.37). Tooth loss and clinical parameters of periodontal disease such as pocket depth and attachment level obtained from six sites of every tooth were recorded. Also, an interview was conducted about medical and dental history. The results indicated chronic generalized periodontitis was more prevalent in individuals with plaque (61,36%) and subclinical atherosclerosis (21,59%) than less extensive periodontal disease (P=0,0001). The severity of periodontal disease was also prevalent in the stenotic group (58,82%) compared to the mild/moderate periodontitis group (P=0,0242). Additionally, fewer teeth (P=0.0007) were also more prevalent in the group with stenosis. Thus we can conclude that this study found the association between partial stenosis in the intima-media wall of carotidio system (atheromatous plaques) and subclinical atherosclerosis and the extent and severity of chronic generalized periodontal disease and numbers of teeth.A infecção e a inflamação crônicas são consideradas fatores de risco para o desenvolvimento das doenças cardiovasculares. Recentes estudos indicam que a periodontite severa pode influenciar no aumento de citocinas pró-inflamatórias e marcadores de inflamação associados com os eventos cardiovasculares. A espessura da camada íntima-média da artéria carótida é considerada um marcador de risco para as doenças cardiovasculares. O propósito deste estudo foi relacionar a doença periodontal com o espessamento mio-intimal das artérias carótidas. Medidas não invasivas dos sistemas carotídeos (artéria carótida comum, externa e interna) esquerdo e direito foram feitas com ultrassonografia de alta resolução em 217 sujeitos com idade média de 62,28 (DP: 10,37). A presença do elemento dentário e os parâmetros clínicos de doença periodontal, como as medidas de bolsas periodontais e o nível de inserção clínico, foram obtidos de seis sítios de cada dente presente. Também, foi realizada uma entrevista com histórico médico-odontológico. Os resultados indicam que a periodontite crônica generalizada foi mais prevalente em indivíduos que apresentavam placas ateromatosas (61,36%) e espessamento médio-intimal (aterosclerose sublínica) (21,59%), em comparação aos pacientes com menor extensão de doença periodontal (P=0,0001). A severidade da doença periodontal também esteve mais prevalente no grupo estenótico (58,82%) (P=0,0242), se comparado ao grupo com periodontite média/moderada. Adicionalmente, o menor número de dentes (P=0,0007) também foi mais prevalente no grupo com estenose. Neste estudo, observamos, portanto, a associação entre a estenose parcial na parede íntima-média no sistema carotídeo (placas ateromatosas) e a aterosclerose subclinical, com a presença da doença periodontal crônica em maior extensão e severidade e o números de dentes.Submitted by Janser dos Santos Nascimento (janser.nascimento@unigranrio.com.br) on 2016-10-19T17:24:00Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Lisiane Castagna.pdf: 1851883 bytes, checksum: ed9ecf1ff76d1c08bcefd0f284be0be1 (MD5)Made available in DSpace on 2016-10-19T17:24:00Z (GMT). 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dc.title.por.fl_str_mv Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
title Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
spellingShingle Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
Castagna, Lisiane
Odontologia
Periodontia
Doenças periodontais - Complicações
Doenças cardiovasculares
ODONTOLOGIA::PERIODONTIA
title_short Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
title_full Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
title_fullStr Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
title_full_unstemmed Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
title_sort Relação da doença periodontal com espessura da parede íntima-média da artéria carótida
author Castagna, Lisiane
author_facet Castagna, Lisiane
author_role author
dc.contributor.advisor1.fl_str_mv Tinoco, Eduardo Muniz Barretto
dc.contributor.referee1.fl_str_mv Silva, Denise Gomes da
dc.contributor.referee2.fl_str_mv Falabella, Marcio Eduardo Vieira
dc.contributor.referee3.fl_str_mv Fischer, Ricardo Guimarães
dc.contributor.author.fl_str_mv Castagna, Lisiane
contributor_str_mv Tinoco, Eduardo Muniz Barretto
Silva, Denise Gomes da
Falabella, Marcio Eduardo Vieira
Fischer, Ricardo Guimarães
dc.subject.por.fl_str_mv Odontologia
Periodontia
Doenças periodontais - Complicações
Doenças cardiovasculares
topic Odontologia
Periodontia
Doenças periodontais - Complicações
Doenças cardiovasculares
ODONTOLOGIA::PERIODONTIA
dc.subject.cnpq.fl_str_mv ODONTOLOGIA::PERIODONTIA
description Chronic infections and inflammation are considered risk factors for the development of cardiovascular diseases. Recent studies indicate that severe periodontitis may increase proinflammatory cytokines and markers of inflammation associated with increased risk of coronary disease and stroke. The intima-media layer thickness of the carotid artery is considered a risk marker for cardiovascular diseases. The purpose of this study was to investigate the relationship between periodontal disease and the myo-intimal thickening of carotid arteries. Noninvasive measurements of the intima-media of the common, internal and external carotid artery bilaterally were made in 217 subjects with mean age of 62.28 (SD:10.37). Tooth loss and clinical parameters of periodontal disease such as pocket depth and attachment level obtained from six sites of every tooth were recorded. Also, an interview was conducted about medical and dental history. The results indicated chronic generalized periodontitis was more prevalent in individuals with plaque (61,36%) and subclinical atherosclerosis (21,59%) than less extensive periodontal disease (P=0,0001). The severity of periodontal disease was also prevalent in the stenotic group (58,82%) compared to the mild/moderate periodontitis group (P=0,0242). Additionally, fewer teeth (P=0.0007) were also more prevalent in the group with stenosis. Thus we can conclude that this study found the association between partial stenosis in the intima-media wall of carotidio system (atheromatous plaques) and subclinical atherosclerosis and the extent and severity of chronic generalized periodontal disease and numbers of teeth.
publishDate 2009
dc.date.issued.fl_str_mv 2009-09-09
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dc.identifier.citation.fl_str_mv Castagna, Lisiane. Relação da doença periodontal com espessura da parede íntima-média da artéria carótida. 2009. [72] f. Dissertação (mestrado em Odontologia) - Universidade do Grande Rio “Prof. José de Souza Herdy”, Duque de Caxias.
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identifier_str_mv Castagna, Lisiane. Relação da doença periodontal com espessura da parede íntima-média da artéria carótida. 2009. [72] f. Dissertação (mestrado em Odontologia) - Universidade do Grande Rio “Prof. José de Souza Herdy”, Duque de Caxias.
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