Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UNIGRANRIO |
Texto Completo: | http://localhost:8080/tede/handle/tede/222 |
Resumo: | The use of biomaterials in dental surgery has become an important area of research. This material can be used for the purpose of filling defects, replace portions bone, bone augmentation, facilitate or enhance the repair of bone defects by bone conduction, providing mechanical support to the membrane and stabilize the blood clot .The geometry of these biomaterials to promote invagination of blood vessels. For this, it needs to be porous and have interconnected macropores. The surface of bone substitutes are determined by their chemical composition, microporosity, surface roughness, crystallinity and crystal size.This study presents the results of histomorphometric use of three commercially available substitutes. The model of defects in the calvaria of rabbits used is well established in the literature, with consistent results. In this case, both the defects filled with the biomaterials showed better distribution in the newly formed bone , lower volume loss and reduced migration into the soft tissue defect , then the conclusion is that both bone substitutes showed used biocompatibility , not negatively affect the repair process. However, the synthetic biomaterial NanoSynt had higher levels of bone formation and maintenance of the defect when compared to materials BoneCeramic ® and Bio-Oss ® during the two periods in vivo in the present study (4 and 8 weeks). |
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Senna , Plinio MendesGranato, RodrigoVieira, Victor Talarico LealMarin, CharlesSotto Maior, Bruno SallesOliveira, Michel Anderson Galvão de2018-07-12T20:33:45Z2015-08-11Oliveira, Michel Anderson Galvão de. Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo. 2015. 28 f. Dissertação( Programa de Pós-Graduação em Odontologia) - Universidade do Grande Rio, Duque de Caxias.http://localhost:8080/tede/handle/tede/222The use of biomaterials in dental surgery has become an important area of research. This material can be used for the purpose of filling defects, replace portions bone, bone augmentation, facilitate or enhance the repair of bone defects by bone conduction, providing mechanical support to the membrane and stabilize the blood clot .The geometry of these biomaterials to promote invagination of blood vessels. For this, it needs to be porous and have interconnected macropores. The surface of bone substitutes are determined by their chemical composition, microporosity, surface roughness, crystallinity and crystal size.This study presents the results of histomorphometric use of three commercially available substitutes. The model of defects in the calvaria of rabbits used is well established in the literature, with consistent results. In this case, both the defects filled with the biomaterials showed better distribution in the newly formed bone , lower volume loss and reduced migration into the soft tissue defect , then the conclusion is that both bone substitutes showed used biocompatibility , not negatively affect the repair process. However, the synthetic biomaterial NanoSynt had higher levels of bone formation and maintenance of the defect when compared to materials BoneCeramic ® and Bio-Oss ® during the two periods in vivo in the present study (4 and 8 weeks).O uso de biomateriais em cirurgias odontológicas tornou-se uma importante área de pesquisa. Esses materiais podem ser utilizados com o objetivo de preencher defeitos, substituir porções ósseas, aumentar o tecido ósseo, facilitar ou melhorar o reparo dos defeitos ósseos pela osteocondução, fornecer suporte mecânico para membranas e estabilizar o coágulo sanguíneo. A geometria desses biomateriais deve favorecer a proliferação de vasos sanguíneos. Para isso, o mesmo precisa ser poroso, com macroporos interconectados. As características superficiais dos substitutos ósseos são determinadas pela sua composição química, microporosidade, rugosidade superficial, cristalinidade e tamanho do cristal.Este estudo apresenta os resultados histomorfométricos do uso de três substitutos comercialmente disponíveis. O modelo de defeitos em calvária de coelhos utilizado já está consolidado na literatura, com resultados consistentes. Neste caso, os defeitos preenchidos com os biomateriais, apresentaram melhor distribuição do tecido ósseo neoformado, menor perda de volume e menor migração de tecido mole para o interior do defeito, concluindo-se então que todos os substitutos ósseos utilizados apresentaram características de biocompatibilidade, não interferindo negativamente no processo de reparo. Entretanto, o biomaterial sintético NanoSynt apresentou maior nível de formação óssea e manutenção do espaço do defeito quando comparado aos materiais Boneceramic® e Bio-Oss® durante os dois períodos in vivo do presente estudo (4 e 8 semanas).Submitted by Patricia Vieira Silva (patricia.silva@unigranrio.com.br) on 2018-07-12T20:33:45Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Michel Anderson Galvão de Oliveira 2015.pdf: 1479195 bytes, checksum: 0dabe5a385c1b82fa59fe9634d051ca9 (MD5)Made available in DSpace on 2018-07-12T20:33:45Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Michel Anderson Galvão de Oliveira 2015.pdf: 1479195 bytes, checksum: 0dabe5a385c1b82fa59fe9634d051ca9 (MD5) Previous issue date: 2015-08-11application/pdfporUniversidade do Grande RioPrograma de Pós-Graduação em OdontologiaUNIGRANRIOBrasilUnigranrio::Odontologiahttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessOdontologiaOsteoconduçãoRegeneração ósseaHistomorfometriaOdontologiaAvaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisreponame:Biblioteca Digital de Teses e Dissertações da UNIGRANRIOinstname:Universidade do Grande Rio (UNIGRANRIO)instacron:UNIGRANRIOLICENSElicense.txtlicense.txttext/plain; charset=utf-81982http://localhost:8080/tede/bitstream/tede/222/1/license.txt4a50535e8405f611398e6e2d408dbd1bMD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://localhost:8080/tede/bitstream/tede/222/2/license_url4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://localhost:8080/tede/bitstream/tede/222/3/license_textd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://localhost:8080/tede/bitstream/tede/222/4/license_rdfd41d8cd98f00b204e9800998ecf8427eMD54ORIGINALMichel Anderson Galvão de Oliveira 2015.pdfMichel Anderson Galvão de Oliveira 2015.pdfapplication/pdf1479195http://localhost:8080/tede/bitstream/tede/222/5/Michel+Anderson+Galv%C3%A3o+de+Oliveira+2015.pdf0dabe5a385c1b82fa59fe9634d051ca9MD55tede/2222018-07-12 17:33:45.192oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttp://tede.unigranrio.edu.br/PUBhttp://tede.unigranrio.edu.br/oai/requestrepositorio@instituicao.br||repositorio@instituicao.bropendoar:2018-07-12T20:33:45Biblioteca Digital de Teses e Dissertações da UNIGRANRIO - Universidade do Grande Rio (UNIGRANRIO)false |
dc.title.por.fl_str_mv |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
title |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
spellingShingle |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo Oliveira, Michel Anderson Galvão de Odontologia Osteocondução Regeneração óssea Histomorfometria Odontologia |
title_short |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
title_full |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
title_fullStr |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
title_full_unstemmed |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
title_sort |
Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo |
author |
Oliveira, Michel Anderson Galvão de |
author_facet |
Oliveira, Michel Anderson Galvão de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Senna , Plinio Mendes |
dc.contributor.advisor-co1.fl_str_mv |
Granato, Rodrigo |
dc.contributor.referee1.fl_str_mv |
Vieira, Victor Talarico Leal |
dc.contributor.referee2.fl_str_mv |
Marin, Charles |
dc.contributor.referee3.fl_str_mv |
Sotto Maior, Bruno Salles |
dc.contributor.author.fl_str_mv |
Oliveira, Michel Anderson Galvão de |
contributor_str_mv |
Senna , Plinio Mendes Granato, Rodrigo Vieira, Victor Talarico Leal Marin, Charles Sotto Maior, Bruno Salles |
dc.subject.por.fl_str_mv |
Odontologia Osteocondução Regeneração óssea Histomorfometria |
topic |
Odontologia Osteocondução Regeneração óssea Histomorfometria Odontologia |
dc.subject.cnpq.fl_str_mv |
Odontologia |
description |
The use of biomaterials in dental surgery has become an important area of research. This material can be used for the purpose of filling defects, replace portions bone, bone augmentation, facilitate or enhance the repair of bone defects by bone conduction, providing mechanical support to the membrane and stabilize the blood clot .The geometry of these biomaterials to promote invagination of blood vessels. For this, it needs to be porous and have interconnected macropores. The surface of bone substitutes are determined by their chemical composition, microporosity, surface roughness, crystallinity and crystal size.This study presents the results of histomorphometric use of three commercially available substitutes. The model of defects in the calvaria of rabbits used is well established in the literature, with consistent results. In this case, both the defects filled with the biomaterials showed better distribution in the newly formed bone , lower volume loss and reduced migration into the soft tissue defect , then the conclusion is that both bone substitutes showed used biocompatibility , not negatively affect the repair process. However, the synthetic biomaterial NanoSynt had higher levels of bone formation and maintenance of the defect when compared to materials BoneCeramic ® and Bio-Oss ® during the two periods in vivo in the present study (4 and 8 weeks). |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-08-11 |
dc.date.accessioned.fl_str_mv |
2018-07-12T20:33:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
Oliveira, Michel Anderson Galvão de. Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo. 2015. 28 f. Dissertação( Programa de Pós-Graduação em Odontologia) - Universidade do Grande Rio, Duque de Caxias. |
dc.identifier.uri.fl_str_mv |
http://localhost:8080/tede/handle/tede/222 |
identifier_str_mv |
Oliveira, Michel Anderson Galvão de. Avaliação histomorfométrica de 3 substitutos ósseos em odontologia: estudo in vivo. 2015. 28 f. Dissertação( Programa de Pós-Graduação em Odontologia) - Universidade do Grande Rio, Duque de Caxias. |
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Programa de Pós-Graduação em Odontologia |
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UNIGRANRIO |
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Universidade do Grande Rio |
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