Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/28692 https://dx.doi.org/10.1590/0037-8682-0104-2013 |
Resumo: | We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making. |
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Treatment of American tegumentary leishmaniasis in special populations : a summary of evidenceLeishmaniose tegumentar americanaPopulações especiaisLeishmaniose - tratamentoWe aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making.Faculdade de Medicina (FMD)Sociedade Brasileira de Medicina Tropical - SBMT2017-12-07T05:02:25Z2017-12-07T05:02:25Z2013-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.http://repositorio.unb.br/handle/10482/28692https://dx.doi.org/10.1590/0037-8682-0104-2013Revista da Sociedade Brasileira de Medicina Tropical - (CC BY-NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.info:eu-repo/semantics/openAccessSilva, Juliana Saboia Fontenele eGalvão, Taís FreirePereira, Maurício GomesSilva, Marcus Tolentinoengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-25T20:29:52Zoai:repositorio.unb.br:10482/28692Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-25T20:29:52Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
title |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
spellingShingle |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence Silva, Juliana Saboia Fontenele e Leishmaniose tegumentar americana Populações especiais Leishmaniose - tratamento |
title_short |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
title_full |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
title_fullStr |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
title_full_unstemmed |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
title_sort |
Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence |
author |
Silva, Juliana Saboia Fontenele e |
author_facet |
Silva, Juliana Saboia Fontenele e Galvão, Taís Freire Pereira, Maurício Gomes Silva, Marcus Tolentino |
author_role |
author |
author2 |
Galvão, Taís Freire Pereira, Maurício Gomes Silva, Marcus Tolentino |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Silva, Juliana Saboia Fontenele e Galvão, Taís Freire Pereira, Maurício Gomes Silva, Marcus Tolentino |
dc.subject.por.fl_str_mv |
Leishmaniose tegumentar americana Populações especiais Leishmaniose - tratamento |
topic |
Leishmaniose tegumentar americana Populações especiais Leishmaniose - tratamento |
description |
We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-12 2017-12-07T05:02:25Z 2017-12-07T05:02:25Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
SILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020. http://repositorio.unb.br/handle/10482/28692 https://dx.doi.org/10.1590/0037-8682-0104-2013 |
identifier_str_mv |
SILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020. |
url |
http://repositorio.unb.br/handle/10482/28692 https://dx.doi.org/10.1590/0037-8682-0104-2013 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
publisher.none.fl_str_mv |
Sociedade Brasileira de Medicina Tropical - SBMT |
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reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
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UNB |
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UNB |
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Repositório Institucional da UnB |
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Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
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1814508410843955200 |