Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence

Detalhes bibliográficos
Autor(a) principal: Silva, Juliana Saboia Fontenele e
Data de Publicação: 2013
Outros Autores: Galvão, Taís Freire, Pereira, Maurício Gomes, Silva, Marcus Tolentino
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio.unb.br/handle/10482/28692
https://dx.doi.org/10.1590/0037-8682-0104-2013
Resumo: We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making.
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spelling Treatment of American tegumentary leishmaniasis in special populations : a summary of evidenceLeishmaniose tegumentar americanaPopulações especiaisLeishmaniose - tratamentoWe aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making.Faculdade de Medicina (FMD)Sociedade Brasileira de Medicina Tropical - SBMT2017-12-07T05:02:25Z2017-12-07T05:02:25Z2013-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.http://repositorio.unb.br/handle/10482/28692https://dx.doi.org/10.1590/0037-8682-0104-2013Revista da Sociedade Brasileira de Medicina Tropical - (CC BY-NC) - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.info:eu-repo/semantics/openAccessSilva, Juliana Saboia Fontenele eGalvão, Taís FreirePereira, Maurício GomesSilva, Marcus Tolentinoengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-25T20:29:52Zoai:repositorio.unb.br:10482/28692Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-25T20:29:52Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
title Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
spellingShingle Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
Silva, Juliana Saboia Fontenele e
Leishmaniose tegumentar americana
Populações especiais
Leishmaniose - tratamento
title_short Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
title_full Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
title_fullStr Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
title_full_unstemmed Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
title_sort Treatment of American tegumentary leishmaniasis in special populations : a summary of evidence
author Silva, Juliana Saboia Fontenele e
author_facet Silva, Juliana Saboia Fontenele e
Galvão, Taís Freire
Pereira, Maurício Gomes
Silva, Marcus Tolentino
author_role author
author2 Galvão, Taís Freire
Pereira, Maurício Gomes
Silva, Marcus Tolentino
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Juliana Saboia Fontenele e
Galvão, Taís Freire
Pereira, Maurício Gomes
Silva, Marcus Tolentino
dc.subject.por.fl_str_mv Leishmaniose tegumentar americana
Populações especiais
Leishmaniose - tratamento
topic Leishmaniose tegumentar americana
Populações especiais
Leishmaniose - tratamento
description We aimed to assess and synthesize the information available in the literature regarding the treatment of American tegumentary leishmaniasis in special populations. We searched MEDLINE (via PubMed), EMBASE, LILACS, SciELO, Scopus, Cochrane Library and mRCT databases to identify clinical trials and observational studies that assessed the pharmacological treatment of the following groups of patients: pregnant women, nursing mothers, children, the elderly, individuals with chronic diseases and individuals with suppressed immune systems. The quality of evidence was assessed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The available evidence suggests that the treatments of choice for each population or disease entity are as follows: nursing mothers and children (meglumine antimoniate or pentamidine), patients with renal disease (amphotericin B or miltefosine), patients with heart disease (amphotericin B, miltefosine or pentamidine), immunosuppressed patients (liposomal amphotericin), the elderly (meglumine antimoniate), pregnant women (amphotericin B) and patients with liver disease (no evidence available). The quality of evidence is low or very low for all groups. Accurate controlled studies are required to fill in the gaps in evidence for treatment in special populations. Post-marketing surveillance programs could also collect relevant information to guide treatment decision-making.
publishDate 2013
dc.date.none.fl_str_mv 2013-12
2017-12-07T05:02:25Z
2017-12-07T05:02:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv SILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.
http://repositorio.unb.br/handle/10482/28692
https://dx.doi.org/10.1590/0037-8682-0104-2013
identifier_str_mv SILVA, Juliana Saboia Fontenele e et al. Treatment of American tegumentary leishmaniasis in special populations: a summary of evidence. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 6, p. 669-677, nov./dez. 2013. DOI: https://doi.org/10.1590/0037-8682-0104-2013. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822013000600669&lng=en&tlng=en. Acesso em: 14 set. 2020.
url http://repositorio.unb.br/handle/10482/28692
https://dx.doi.org/10.1590/0037-8682-0104-2013
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
publisher.none.fl_str_mv Sociedade Brasileira de Medicina Tropical - SBMT
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
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institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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