Bacterial and fungal colonization of burn wounds
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/26335 https://dx.doi.org/10.1590/S0074-02762005000500014 |
Resumo: | A prospective study of fungal and bacterial flora of burn wounds was carried out from February 2004 to February 2005 at the Burns Unit of Hospital Regional da Asa Norte, Brasília, Brazil. During the period of the study, 203 patients were treated at the Burns Unit. Wound swab cultures were assessed at weekly intervals for four weeks. Three hundred and fifty four sampling procedures (surface swabs) were performed from the burn wounds. The study revealed that bacterial colonization reached 86.6% within the first week. Although the gram-negative organisms, as a group, were more predominant, Staphylococcus aureus (28.4%) was the most prevalent organism in the first week. It was however surpassed by Pseudomonas aeruginosa form third week onwards. For S. aureus and P. aeruginosa vancomycin and polymyxin were found to be the most effective drugs. Most of the isolates showed high level resistance to antimicrobial agents. Fungi were found to colonize the burn wound late during the second week postburn, with a peak incidence during the third and fourth weeks. Species identification of fungi revealed that Candida tropicalis was the most predominant, followed by Candida parapsilosis. It is crucial for every burn institution to determine the specific pattern of burn wound microbial colonization, the time-related changes in the dominant flora, and the antimicrobial sensitivity profiles. This would enable early treatment of imminent septic episodes with proper empirical systemic antibiotics, without waiting for culture results, thus improving the overall infection-related morbidity and mortality. |
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Bacterial and fungal colonization of burn woundsQueimadurasInfecçãoA prospective study of fungal and bacterial flora of burn wounds was carried out from February 2004 to February 2005 at the Burns Unit of Hospital Regional da Asa Norte, Brasília, Brazil. During the period of the study, 203 patients were treated at the Burns Unit. Wound swab cultures were assessed at weekly intervals for four weeks. Three hundred and fifty four sampling procedures (surface swabs) were performed from the burn wounds. The study revealed that bacterial colonization reached 86.6% within the first week. Although the gram-negative organisms, as a group, were more predominant, Staphylococcus aureus (28.4%) was the most prevalent organism in the first week. It was however surpassed by Pseudomonas aeruginosa form third week onwards. For S. aureus and P. aeruginosa vancomycin and polymyxin were found to be the most effective drugs. Most of the isolates showed high level resistance to antimicrobial agents. Fungi were found to colonize the burn wound late during the second week postburn, with a peak incidence during the third and fourth weeks. Species identification of fungi revealed that Candida tropicalis was the most predominant, followed by Candida parapsilosis. It is crucial for every burn institution to determine the specific pattern of burn wound microbial colonization, the time-related changes in the dominant flora, and the antimicrobial sensitivity profiles. This would enable early treatment of imminent septic episodes with proper empirical systemic antibiotics, without waiting for culture results, thus improving the overall infection-related morbidity and mortality.Faculdade de Medicina (FMD)Instituto Oswaldo Cruz, Ministério da Saúde2017-12-07T04:42:03Z2017-12-07T04:42:03Z2005-08info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfMACEDO, Jefferson Lessa Soares de; SANTOS, João Barberino. Bacterial and fungal colonization of burn wounds. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 535-539, ago. 2005. DOI: https://doi.org/10.1590/S0074-02762005000500014. Disponível: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000500014&lng=en&nrm=iso. Acesso: 19 mar. 2021.http://repositorio.unb.br/handle/10482/26335https://dx.doi.org/10.1590/S0074-02762005000500014Memórias do Instituto Oswaldo Cruz - All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License (CC BY NC 4.0). Fonte: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000500014&lng=en&tlng=en. Acesso em: 19 mar. 2021.info:eu-repo/semantics/openAccessMacedo, Jefferson Lessa Soares deSantos, João Barberinoengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2023-08-22T18:40:52Zoai:repositorio.unb.br:10482/26335Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2023-08-22T18:40:52Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Bacterial and fungal colonization of burn wounds |
title |
Bacterial and fungal colonization of burn wounds |
spellingShingle |
Bacterial and fungal colonization of burn wounds Macedo, Jefferson Lessa Soares de Queimaduras Infecção |
title_short |
Bacterial and fungal colonization of burn wounds |
title_full |
Bacterial and fungal colonization of burn wounds |
title_fullStr |
Bacterial and fungal colonization of burn wounds |
title_full_unstemmed |
Bacterial and fungal colonization of burn wounds |
title_sort |
Bacterial and fungal colonization of burn wounds |
author |
Macedo, Jefferson Lessa Soares de |
author_facet |
Macedo, Jefferson Lessa Soares de Santos, João Barberino |
author_role |
author |
author2 |
Santos, João Barberino |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Macedo, Jefferson Lessa Soares de Santos, João Barberino |
dc.subject.por.fl_str_mv |
Queimaduras Infecção |
topic |
Queimaduras Infecção |
description |
A prospective study of fungal and bacterial flora of burn wounds was carried out from February 2004 to February 2005 at the Burns Unit of Hospital Regional da Asa Norte, Brasília, Brazil. During the period of the study, 203 patients were treated at the Burns Unit. Wound swab cultures were assessed at weekly intervals for four weeks. Three hundred and fifty four sampling procedures (surface swabs) were performed from the burn wounds. The study revealed that bacterial colonization reached 86.6% within the first week. Although the gram-negative organisms, as a group, were more predominant, Staphylococcus aureus (28.4%) was the most prevalent organism in the first week. It was however surpassed by Pseudomonas aeruginosa form third week onwards. For S. aureus and P. aeruginosa vancomycin and polymyxin were found to be the most effective drugs. Most of the isolates showed high level resistance to antimicrobial agents. Fungi were found to colonize the burn wound late during the second week postburn, with a peak incidence during the third and fourth weeks. Species identification of fungi revealed that Candida tropicalis was the most predominant, followed by Candida parapsilosis. It is crucial for every burn institution to determine the specific pattern of burn wound microbial colonization, the time-related changes in the dominant flora, and the antimicrobial sensitivity profiles. This would enable early treatment of imminent septic episodes with proper empirical systemic antibiotics, without waiting for culture results, thus improving the overall infection-related morbidity and mortality. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-08 2017-12-07T04:42:03Z 2017-12-07T04:42:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
MACEDO, Jefferson Lessa Soares de; SANTOS, João Barberino. Bacterial and fungal colonization of burn wounds. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 535-539, ago. 2005. DOI: https://doi.org/10.1590/S0074-02762005000500014. Disponível: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000500014&lng=en&nrm=iso. Acesso: 19 mar. 2021. http://repositorio.unb.br/handle/10482/26335 https://dx.doi.org/10.1590/S0074-02762005000500014 |
identifier_str_mv |
MACEDO, Jefferson Lessa Soares de; SANTOS, João Barberino. Bacterial and fungal colonization of burn wounds. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 5, p. 535-539, ago. 2005. DOI: https://doi.org/10.1590/S0074-02762005000500014. Disponível: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000500014&lng=en&nrm=iso. Acesso: 19 mar. 2021. |
url |
http://repositorio.unb.br/handle/10482/26335 https://dx.doi.org/10.1590/S0074-02762005000500014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
instacron_str |
UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
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1810580888420876288 |