Síntese de análogo de brassinoesteróide a partir de vespertilina

• Autor(a) principal: Gárate, José L. M.
• Data de Publicação: 1998
• Outros Autores: Magalhães, Gouvan C. de, Romeiro, Luiz A. S.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UnB
• Texto Completo: http://repositorio.unb.br/handle/10482/25451; https://dx.doi.org/10.1590/S0100-40421998000600011
• topic: vespertiline; brassinosteroids; plant growth-promoting steroids

In the last years, several research groups have been working on the synthesis of new steroidal plant hormones called brassinosteroids (BS), which promote plant growth and better crops. Many synthetic targets and applications of these compounds and their analogues have been described in the literature. From Solanum species of the Distrito Federal, we isolated the steroidal alkaloid solasodine, which was then converted into our starting material, vespertiline. By functionalization of rings A and B, we have synthesized a new analogue of BS, with a 2alpha,3alpha-dihydroxy-6-one structure, typical of the naturally occurring BS castasterone, the immediate biosynthetic precursor of brassinolide.