Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats

Detalhes bibliográficos
Autor(a) principal: Yamashita, Hiromi
Data de Publicação: 2021
Outros Autores: Zeredo, Jorge Luis Lopes, Toda, Kazuo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio2.unb.br/jspui/handle/10482/48022
https://doi.org/10.51507/j.jams.2021.14.4.167
https://orcid.org/0000-0002-2850-0731
https://orcid.org/0000-0003-0338-5850
https://orcid.org/0000-0002-8848-8017
Resumo: Background: Electroacupuncture is one of the most popular physical treatments for clinical pain, but the potential influence of a patient’s age on the effectiveness of electroacupuncture treatment has not been clearly established. Objectives: The present study aimed to detect a potential difference in electroacupuncture- induced analgesia between juvenile and adult rats. Methods: In this study, we investigated the effects of electroacupuncture treatment on the nociceptive jaw-opening reflex evoked by tooth-pulp stimulation in juvenile and adult rats. Results: Our results showed there were age differences in electroacupuncture-induced analgesic effects in rats, especially with naloxone antagonization. The ratio of naloxonereversibility against electroacupuncture analgesia was greater in adult rats than in juvenile rats. Conclusion: These results suggest that electroacupuncture analgesia is produced mainly by the non-opioid system in juvenile rats and by the opioid system in adult rats.
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spelling Yamashita, HiromiZeredo, Jorge Luis LopesToda, KazuoNagasaki University, Institute of Biomedical Sciences, Forensic Dental ScienceUniversity of Brasilia, Ceilandia Campus, Graduate Program in Health Science and TechnologNagasaki University, Institute of Biomedical Sciences, Integrative Sensory Physiology2024-03-22T12:44:53Z2024-03-22T12:44:53Z2021-08-31YAMASHITA, Hiromi; ZEREDO, Jorge Luis Lopes; TODA, Kazuo. Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats. Journal of Acupuncture and Meridian Studies, [S.l.], v. 14, n. 4, 31 ago 2021. Disponível em: https://doi.org/10.51507/j.jams.2021.14.4.167. Acesso em: 20 mar 2024.http://repositorio2.unb.br/jspui/handle/10482/48022https://doi.org/10.51507/j.jams.2021.14.4.167https://orcid.org/0000-0002-2850-0731https://orcid.org/0000-0003-0338-5850https://orcid.org/0000-0002-8848-8017engMedical Association of Pharmacopuncture Institute(CC BY NC) This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/ licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.info:eu-repo/semantics/openAccessAge differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleEletroacupunturaAnalgesiaMandíbulaBackground: Electroacupuncture is one of the most popular physical treatments for clinical pain, but the potential influence of a patient’s age on the effectiveness of electroacupuncture treatment has not been clearly established. Objectives: The present study aimed to detect a potential difference in electroacupuncture- induced analgesia between juvenile and adult rats. Methods: In this study, we investigated the effects of electroacupuncture treatment on the nociceptive jaw-opening reflex evoked by tooth-pulp stimulation in juvenile and adult rats. Results: Our results showed there were age differences in electroacupuncture-induced analgesic effects in rats, especially with naloxone antagonization. The ratio of naloxonereversibility against electroacupuncture analgesia was greater in adult rats than in juvenile rats. Conclusion: These results suggest that electroacupuncture analgesia is produced mainly by the non-opioid system in juvenile rats and by the opioid system in adult rats.Faculdade UnB Ceilândia (FCE)Colegiado de Bases Biológicas e da Saúde (FCE-BASES)Programa de Pós-Graduação em Ciência e Tecnologia da Saúdereponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNBORIGINALARTIGO_AgeDifferencesNaloxone.pdfARTIGO_AgeDifferencesNaloxone.pdfapplication/pdf432497http://repositorio2.unb.br/jspui/bitstream/10482/48022/1/ARTIGO_AgeDifferencesNaloxone.pdfd794077183e3399d76222c0a3d41e721MD51open accessLICENSElicense.txtlicense.txttext/plain102http://repositorio2.unb.br/jspui/bitstream/10482/48022/2/license.txtaed4704d04bb260d4decd80db311aaa5MD52open access10482/480222024-03-22 12:24:43.653open accessoai:repositorio2.unb.br:10482/48022U3VibWlzc8OjbyBlZmV0aXZhZGEgZGUgYWNvcmRvIGNvbSBsaWNlbsOnYSBjb25jZWRpZGEgcGVsbyBhdXRvciBlL291IGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcy4KBiblioteca Digital de Teses e DissertaçõesPUBhttps://repositorio.unb.br/oai/requestopendoar:2024-03-22T15:24:43Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.pt_BR.fl_str_mv Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
title Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
spellingShingle Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
Yamashita, Hiromi
Eletroacupuntura
Analgesia
Mandíbula
title_short Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
title_full Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
title_fullStr Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
title_full_unstemmed Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
title_sort Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats
author Yamashita, Hiromi
author_facet Yamashita, Hiromi
Zeredo, Jorge Luis Lopes
Toda, Kazuo
author_role author
author2 Zeredo, Jorge Luis Lopes
Toda, Kazuo
author2_role author
author
dc.contributor.affiliation.pt_BR.fl_str_mv Nagasaki University, Institute of Biomedical Sciences, Forensic Dental Science
University of Brasilia, Ceilandia Campus, Graduate Program in Health Science and Technolog
Nagasaki University, Institute of Biomedical Sciences, Integrative Sensory Physiology
dc.contributor.author.fl_str_mv Yamashita, Hiromi
Zeredo, Jorge Luis Lopes
Toda, Kazuo
dc.subject.keyword.pt_BR.fl_str_mv Eletroacupuntura
Analgesia
Mandíbula
topic Eletroacupuntura
Analgesia
Mandíbula
description Background: Electroacupuncture is one of the most popular physical treatments for clinical pain, but the potential influence of a patient’s age on the effectiveness of electroacupuncture treatment has not been clearly established. Objectives: The present study aimed to detect a potential difference in electroacupuncture- induced analgesia between juvenile and adult rats. Methods: In this study, we investigated the effects of electroacupuncture treatment on the nociceptive jaw-opening reflex evoked by tooth-pulp stimulation in juvenile and adult rats. Results: Our results showed there were age differences in electroacupuncture-induced analgesic effects in rats, especially with naloxone antagonization. The ratio of naloxonereversibility against electroacupuncture analgesia was greater in adult rats than in juvenile rats. Conclusion: These results suggest that electroacupuncture analgesia is produced mainly by the non-opioid system in juvenile rats and by the opioid system in adult rats.
publishDate 2021
dc.date.issued.fl_str_mv 2021-08-31
dc.date.accessioned.fl_str_mv 2024-03-22T12:44:53Z
dc.date.available.fl_str_mv 2024-03-22T12:44:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv YAMASHITA, Hiromi; ZEREDO, Jorge Luis Lopes; TODA, Kazuo. Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats. Journal of Acupuncture and Meridian Studies, [S.l.], v. 14, n. 4, 31 ago 2021. Disponível em: https://doi.org/10.51507/j.jams.2021.14.4.167. Acesso em: 20 mar 2024.
dc.identifier.uri.fl_str_mv http://repositorio2.unb.br/jspui/handle/10482/48022
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.51507/j.jams.2021.14.4.167
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0002-2850-0731
https://orcid.org/0000-0003-0338-5850
https://orcid.org/0000-0002-8848-8017
identifier_str_mv YAMASHITA, Hiromi; ZEREDO, Jorge Luis Lopes; TODA, Kazuo. Age differences in naloxone reversibility of electroacupuncture on the jaw opening reflex in rats. Journal of Acupuncture and Meridian Studies, [S.l.], v. 14, n. 4, 31 ago 2021. Disponível em: https://doi.org/10.51507/j.jams.2021.14.4.167. Acesso em: 20 mar 2024.
url http://repositorio2.unb.br/jspui/handle/10482/48022
https://doi.org/10.51507/j.jams.2021.14.4.167
https://orcid.org/0000-0002-2850-0731
https://orcid.org/0000-0003-0338-5850
https://orcid.org/0000-0002-8848-8017
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Medical Association of Pharmacopuncture Institute
publisher.none.fl_str_mv Medical Association of Pharmacopuncture Institute
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
bitstream.url.fl_str_mv http://repositorio2.unb.br/jspui/bitstream/10482/48022/1/ARTIGO_AgeDifferencesNaloxone.pdf
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