Clinical effectiveness of screening for age-related macular degeneration : a systematic review

Detalhes bibliográficos
Autor(a) principal: Gomes, Dalila Fernandes
Data de Publicação: 2023
Outros Autores: Curado, Daniel da Silva Pereira, Gomes, Rosângela Maria, Leite, Betânia Ferreira, Ramos, Maíra Catharina, Silva, Everton Nunes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UnB
Texto Completo: http://repositorio2.unb.br/jspui/handle/10482/47611
https://doi.org/10.1371/journal.pone.0294398
https://orcid.org/0000-0002-2864-0806
https://orcid.org/0000-0002-5965-4194
https://orcid.org/0000-0003-3829-975X
https://orcid.org/0000-0001-8747-4185
Resumo: Introduction Age-related macular degeneration (AMD) is an eye disease that occurs in patients over 50 years old. Early diagnosis enables timely treatment to stabilize disease progression. How-ever, the fact that the disease is asymptomatic in its early stages can delay treatment until it progresses. As such, screening in specific contexts can be an early detection tool to reduce the clinical and social impact of the disease. Objective Assess the effectiveness of screening methods for early detection of AMD in adults aged 50 years or older. Methods A systematic review of comparative observational studies on AMD screening methods in those aged 50 years or older, compared with no screening or any other strategy. A literature search was conducted in the MEDLINE (via PubMed), Embase, Cochrane Library and Lilacs database. Results A total of 5,290 studies were identified, three of which met the inclusion criteria and were selected for the systematic review. A total of 8,733 individuals (16,780 eyes) were included in the analysis. The screening methods assessed were based on optical coherence tomography (OCT) compared with color fundus photography, and OCT and telemedicine testing compared to a standard eye exam. Conclusion The systematized data are limited and only suggest satisfactory performance in early screening of the population at risk of developing AMD. OCT and the telemedicine technique showed promising results in AMD screening. However, methodological problems were iden tified in the studies selected and the level of evidence was considered low.
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spelling Clinical effectiveness of screening for age-related macular degeneration : a systematic reviewDegeneração macularTomografiaOlhos - doençasOlhos - doenças - diagnósticoRetinopatia diabéticaIntroduction Age-related macular degeneration (AMD) is an eye disease that occurs in patients over 50 years old. Early diagnosis enables timely treatment to stabilize disease progression. How-ever, the fact that the disease is asymptomatic in its early stages can delay treatment until it progresses. As such, screening in specific contexts can be an early detection tool to reduce the clinical and social impact of the disease. Objective Assess the effectiveness of screening methods for early detection of AMD in adults aged 50 years or older. Methods A systematic review of comparative observational studies on AMD screening methods in those aged 50 years or older, compared with no screening or any other strategy. A literature search was conducted in the MEDLINE (via PubMed), Embase, Cochrane Library and Lilacs database. Results A total of 5,290 studies were identified, three of which met the inclusion criteria and were selected for the systematic review. A total of 8,733 individuals (16,780 eyes) were included in the analysis. The screening methods assessed were based on optical coherence tomography (OCT) compared with color fundus photography, and OCT and telemedicine testing compared to a standard eye exam. Conclusion The systematized data are limited and only suggest satisfactory performance in early screening of the population at risk of developing AMD. OCT and the telemedicine technique showed promising results in AMD screening. However, methodological problems were iden tified in the studies selected and the level of evidence was considered low.Faculdade de Ciências da Saúde (FS)Departamento de Farmácia (FS FAR)Faculdade UnB Ceilândia (FCE)Programa de Pós-Graduação em Saúde ColetivaPlos OneUniversity of Brasilia, Graduate Program in Collective HealthMinistry of Health, Department of Management and Incorporation of Health Technologies, Brasilia, Federal District, BrazilFederal University of Minas Gerais, Department of Social Pharmacy, College of PharmacyUniversity of Brasilia, Faculty of Health Sciences, Department of PharmacyFederal University of Sao Paulo, Paulista School of Medicine, Department of MedicineUniversity of Brasilia, Graduate Program in Collective HealthUniversity of Brasilia, Graduate Program in Collective HealthUniversity of Brasili, Faculty of Ceilandia,Gomes, Dalila FernandesCurado, Daniel da Silva PereiraGomes, Rosângela MariaLeite, Betânia FerreiraRamos, Maíra CatharinaSilva, Everton Nunes2024-01-31T14:24:14Z2024-01-31T14:24:14Z2023-11-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfGOMES, Dalila Fernandes et al. Clinical effectiveness of screening for age-related macular degeneration: a systematic review. Plos One, [S. l.], 16 nov. 2023. DOI: https://doi.org/10.1371/journal.pone.0294398. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0294398. Acesso em: 31 jan. 2024.http://repositorio2.unb.br/jspui/handle/10482/47611https://doi.org/10.1371/journal.pone.0294398https://orcid.org/0000-0002-2864-0806https://orcid.org/0000-0002-5965-4194https://orcid.org/0000-0003-3829-975Xhttps://orcid.org/0000-0001-8747-4185engCopyright: © 2023 Gomes et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-01-31T14:24:14Zoai:repositorio.unb.br:10482/47611Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-01-31T14:24:14Repositório Institucional da UnB - Universidade de Brasília (UnB)false
dc.title.none.fl_str_mv Clinical effectiveness of screening for age-related macular degeneration : a systematic review
title Clinical effectiveness of screening for age-related macular degeneration : a systematic review
spellingShingle Clinical effectiveness of screening for age-related macular degeneration : a systematic review
Gomes, Dalila Fernandes
Degeneração macular
Tomografia
Olhos - doenças
Olhos - doenças - diagnóstico
Retinopatia diabética
title_short Clinical effectiveness of screening for age-related macular degeneration : a systematic review
title_full Clinical effectiveness of screening for age-related macular degeneration : a systematic review
title_fullStr Clinical effectiveness of screening for age-related macular degeneration : a systematic review
title_full_unstemmed Clinical effectiveness of screening for age-related macular degeneration : a systematic review
title_sort Clinical effectiveness of screening for age-related macular degeneration : a systematic review
author Gomes, Dalila Fernandes
author_facet Gomes, Dalila Fernandes
Curado, Daniel da Silva Pereira
Gomes, Rosângela Maria
Leite, Betânia Ferreira
Ramos, Maíra Catharina
Silva, Everton Nunes
author_role author
author2 Curado, Daniel da Silva Pereira
Gomes, Rosângela Maria
Leite, Betânia Ferreira
Ramos, Maíra Catharina
Silva, Everton Nunes
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv University of Brasilia, Graduate Program in Collective Health
Ministry of Health, Department of Management and Incorporation of Health Technologies, Brasilia, Federal District, Brazil
Federal University of Minas Gerais, Department of Social Pharmacy, College of Pharmacy
University of Brasilia, Faculty of Health Sciences, Department of Pharmacy
Federal University of Sao Paulo, Paulista School of Medicine, Department of Medicine
University of Brasilia, Graduate Program in Collective Health
University of Brasilia, Graduate Program in Collective Health
University of Brasili, Faculty of Ceilandia,
dc.contributor.author.fl_str_mv Gomes, Dalila Fernandes
Curado, Daniel da Silva Pereira
Gomes, Rosângela Maria
Leite, Betânia Ferreira
Ramos, Maíra Catharina
Silva, Everton Nunes
dc.subject.por.fl_str_mv Degeneração macular
Tomografia
Olhos - doenças
Olhos - doenças - diagnóstico
Retinopatia diabética
topic Degeneração macular
Tomografia
Olhos - doenças
Olhos - doenças - diagnóstico
Retinopatia diabética
description Introduction Age-related macular degeneration (AMD) is an eye disease that occurs in patients over 50 years old. Early diagnosis enables timely treatment to stabilize disease progression. How-ever, the fact that the disease is asymptomatic in its early stages can delay treatment until it progresses. As such, screening in specific contexts can be an early detection tool to reduce the clinical and social impact of the disease. Objective Assess the effectiveness of screening methods for early detection of AMD in adults aged 50 years or older. Methods A systematic review of comparative observational studies on AMD screening methods in those aged 50 years or older, compared with no screening or any other strategy. A literature search was conducted in the MEDLINE (via PubMed), Embase, Cochrane Library and Lilacs database. Results A total of 5,290 studies were identified, three of which met the inclusion criteria and were selected for the systematic review. A total of 8,733 individuals (16,780 eyes) were included in the analysis. The screening methods assessed were based on optical coherence tomography (OCT) compared with color fundus photography, and OCT and telemedicine testing compared to a standard eye exam. Conclusion The systematized data are limited and only suggest satisfactory performance in early screening of the population at risk of developing AMD. OCT and the telemedicine technique showed promising results in AMD screening. However, methodological problems were iden tified in the studies selected and the level of evidence was considered low.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-16
2024-01-31T14:24:14Z
2024-01-31T14:24:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv GOMES, Dalila Fernandes et al. Clinical effectiveness of screening for age-related macular degeneration: a systematic review. Plos One, [S. l.], 16 nov. 2023. DOI: https://doi.org/10.1371/journal.pone.0294398. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0294398. Acesso em: 31 jan. 2024.
http://repositorio2.unb.br/jspui/handle/10482/47611
https://doi.org/10.1371/journal.pone.0294398
https://orcid.org/0000-0002-2864-0806
https://orcid.org/0000-0002-5965-4194
https://orcid.org/0000-0003-3829-975X
https://orcid.org/0000-0001-8747-4185
identifier_str_mv GOMES, Dalila Fernandes et al. Clinical effectiveness of screening for age-related macular degeneration: a systematic review. Plos One, [S. l.], 16 nov. 2023. DOI: https://doi.org/10.1371/journal.pone.0294398. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0294398. Acesso em: 31 jan. 2024.
url http://repositorio2.unb.br/jspui/handle/10482/47611
https://doi.org/10.1371/journal.pone.0294398
https://orcid.org/0000-0002-2864-0806
https://orcid.org/0000-0002-5965-4194
https://orcid.org/0000-0003-3829-975X
https://orcid.org/0000-0001-8747-4185
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Plos One
publisher.none.fl_str_mv Plos One
dc.source.none.fl_str_mv reponame:Repositório Institucional da UnB
instname:Universidade de Brasília (UnB)
instacron:UNB
instname_str Universidade de Brasília (UnB)
instacron_str UNB
institution UNB
reponame_str Repositório Institucional da UnB
collection Repositório Institucional da UnB
repository.name.fl_str_mv Repositório Institucional da UnB - Universidade de Brasília (UnB)
repository.mail.fl_str_mv repositorio@unb.br
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