Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UnB |
Texto Completo: | http://repositorio.unb.br/handle/10482/26792 https://dx.doi.org/10.1590/S1519-69842006000500020 |
Resumo: | The aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth microdilution to determine the minimum inhibitory concentration (MIC). The morphotyping revealed that all oral C. albicans isolates from children with Down's syndrome promoted the formation of fringes regardless of size, while the control group presented smaller fringes. All oral C. albicans strains produced proteinase, but those with phospholipolytic activity showed greater enzyme capacity in the test group. In vitro susceptibility showed that all oral C. albicans isolates were sensitive to the drugs used. |
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Phenotypic aspects of oral strains of Candida albicans in children with down's syndromeAspectos fenotípicos de cepas de Candida albicans orais em crianças com síndrome de downFenotipagemCandida albicansSíndrome de DownThe aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth microdilution to determine the minimum inhibitory concentration (MIC). The morphotyping revealed that all oral C. albicans isolates from children with Down's syndrome promoted the formation of fringes regardless of size, while the control group presented smaller fringes. All oral C. albicans strains produced proteinase, but those with phospholipolytic activity showed greater enzyme capacity in the test group. In vitro susceptibility showed that all oral C. albicans isolates were sensitive to the drugs used.O objetivo deste artigo foi caracterizar os aspectos biológicos de cepas de C. albicans orais em crianças com síndrome de Down. Estas leveduras foram analisadas quanto aos seus aspectos macromorfológicos e enzimáticos e foram testadas quanto a sua suscetibilidade in vitro a drogas antifúngicas, usando a microdiluição em caldo para a determinação da concentração inibitória mínima (CIM). A morfotipagem revelou que todos os isolados de C. albicans orais de crianças com síndrome de Down induziram à formação de franjas independente do tamanho, enquanto o grupo controle teve franjas menores. Todas as cepas de C. albicans orais produziram proteinase, mas aquelas com atividade fosfolipidolítica mostraram maior capacidade enzimática no grupo teste. A suscetibilidade in vitro mostrou que todos os isolados de C. albicans orais foram sensíveis a drogas empregadas.Em processamentoInstituto Internacional de Ecologia2017-12-07T04:45:54Z2017-12-07T04:45:54Z2006info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBraz. J. Biol.,v.66,n.3,p.939-944,2006http://repositorio.unb.br/handle/10482/26792https://dx.doi.org/10.1590/S1519-69842006000500020Ribeiro, E. L.Scroferneker, M. L.Cavalhaes, M. S.Campos, C. C.Nagato, G. M.Souza, N. A.Ferreira, W. M.Cardoso, C. G.Dias, S. M. S.Pimenta, F. C.Toledo, O. A.info:eu-repo/semantics/openAccessengreponame:Repositório Institucional da UnBinstname:Universidade de Brasília (UnB)instacron:UNB2024-08-28T16:31:53Zoai:repositorio.unb.br:10482/26792Repositório InstitucionalPUBhttps://repositorio.unb.br/oai/requestrepositorio@unb.bropendoar:2024-08-28T16:31:53Repositório Institucional da UnB - Universidade de Brasília (UnB)false |
dc.title.none.fl_str_mv |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome Aspectos fenotípicos de cepas de Candida albicans orais em crianças com síndrome de down |
title |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
spellingShingle |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome Ribeiro, E. L. Fenotipagem Candida albicans Síndrome de Down |
title_short |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
title_full |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
title_fullStr |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
title_full_unstemmed |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
title_sort |
Phenotypic aspects of oral strains of Candida albicans in children with down's syndrome |
author |
Ribeiro, E. L. |
author_facet |
Ribeiro, E. L. Scroferneker, M. L. Cavalhaes, M. S. Campos, C. C. Nagato, G. M. Souza, N. A. Ferreira, W. M. Cardoso, C. G. Dias, S. M. S. Pimenta, F. C. Toledo, O. A. |
author_role |
author |
author2 |
Scroferneker, M. L. Cavalhaes, M. S. Campos, C. C. Nagato, G. M. Souza, N. A. Ferreira, W. M. Cardoso, C. G. Dias, S. M. S. Pimenta, F. C. Toledo, O. A. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, E. L. Scroferneker, M. L. Cavalhaes, M. S. Campos, C. C. Nagato, G. M. Souza, N. A. Ferreira, W. M. Cardoso, C. G. Dias, S. M. S. Pimenta, F. C. Toledo, O. A. |
dc.subject.por.fl_str_mv |
Fenotipagem Candida albicans Síndrome de Down |
topic |
Fenotipagem Candida albicans Síndrome de Down |
description |
The aim of this article is to characterize the biological aspects of oral strains of C. albicans in children with Down's syndrome. These yeasts were analyzed as to their macromorphological and enzymatic aspects and were tested as to their in vitro susceptibility to antifungal drugs using broth microdilution to determine the minimum inhibitory concentration (MIC). The morphotyping revealed that all oral C. albicans isolates from children with Down's syndrome promoted the formation of fringes regardless of size, while the control group presented smaller fringes. All oral C. albicans strains produced proteinase, but those with phospholipolytic activity showed greater enzyme capacity in the test group. In vitro susceptibility showed that all oral C. albicans isolates were sensitive to the drugs used. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006 2017-12-07T04:45:54Z 2017-12-07T04:45:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Braz. J. Biol.,v.66,n.3,p.939-944,2006 http://repositorio.unb.br/handle/10482/26792 https://dx.doi.org/10.1590/S1519-69842006000500020 |
identifier_str_mv |
Braz. J. Biol.,v.66,n.3,p.939-944,2006 |
url |
http://repositorio.unb.br/handle/10482/26792 https://dx.doi.org/10.1590/S1519-69842006000500020 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Instituto Internacional de Ecologia |
publisher.none.fl_str_mv |
Instituto Internacional de Ecologia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UnB instname:Universidade de Brasília (UnB) instacron:UNB |
instname_str |
Universidade de Brasília (UnB) |
instacron_str |
UNB |
institution |
UNB |
reponame_str |
Repositório Institucional da UnB |
collection |
Repositório Institucional da UnB |
repository.name.fl_str_mv |
Repositório Institucional da UnB - Universidade de Brasília (UnB) |
repository.mail.fl_str_mv |
repositorio@unb.br |
_version_ |
1818900867640721408 |