Fatores associados ao estabelecimento da microbiota intestinal neonatal – um estudo de evidências

• Autor(a) principal: Oliveira, Jayane Omena de
• Data de Publicação: 2020
• Outros Autores: Silva, Laís Nicolly Ribeiro da, Arruda, Thamires Ester Alves de, Silva, Davi Porfírio da, Calumby, Rodrigo José Nunes, Moreira, Rossana Teotônio de Farias
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Diversitas Journal
• Texto Completo: https://diversitasjournal.com.br/diversitas_journal/article/view/1184

ABSTRACT: The intestinal tract of an individual is formed by innumerable microorganisms that, together, form the intestinal microbiota, and that act assisting in several metabolic and immunological functions. Thus, its formation begins long before birth and continues to be fixed throughout life, especially during childhood, a period when intestinal functions are still immature. This study aimed to analyze the factors associated with the establishment of the intestinal microbiota of neonates. A descriptive study, an integrative literature review, with a search for articles, was conducted in January 2020, in the LILACS, MEDLINE and SciELO electronic library databases, using the terms "Growth & Development", "Gastrointestinal Microbiome" and Newborn. Of the ninety-five articles recovered, seventeen studies with publication between 2014 and 2019 were included. These studies revealed that factors, such as type of delivery, infant diet, supplementation with probiotics and prebiotics, use of antibiotics and gestational age, are associated with process of establishing the neonatal intestinal microbiota. When analyzing these factors, it appears that adequate neonatal intestinal colonization is associated with exclusive breastfeeding, normal delivery, supplementation with prebiotics and probiotics, while surgical delivery, use of formulas, antibiotics and longer hospital stay, contribute to a microbiota rich in potentially pathogenic microorganisms. KEYWORDS: Intestinal microflora; Neonates; Growth and Development.