Chronic kidney failure following lancehead bite envenoming: a clinical report from the Amazon region

• Autor(a) principal: Pucca,Manuela B.
• Data de Publicação: 2020
• Outros Autores: Franco,Michelle V. S., Medeiros,Jilvando M., Oliveira,Isadora S., Ahmadi,Shirin, Cerni,Felipe A., Zottich,Umberto, Bassoli,Bruna K., Monteiro,Wuelton M., Laustsen,Andreas H.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: The Journal of venomous animals and toxins including tropical diseases (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992020000100401
• topic: Bothrops; Snakebite; Long-term effects; Chronic kidney disease; Renal failure

Abstract Background: Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus is responsible for most snakebite-related deaths and permanent loss of function in human victims in Latin America. Bothrops spp. venom is a complex mixture of different proteins that are known to cause local necrosis, coagulopathy, and acute kidney injury. However, the long-term effects of these viper envenomings have remained largely understudied. Case presentation: Here, we present a case report of a 46-years old female patient from Las Claritas, Venezuela, who was envenomed by a snake from the Bothrops genus. The patient was followed for a 10-year period, during which she presented oliguric renal failure, culminating in kidney failure 60 months after the envenoming. Conclusion: In Latin America, especially in Brazil, where there is a high prevalence of Bothrops envenoming, it may be relevant to establish long-term outpatient programs. This would reduce late adverse events, such as chronic kidney disease, and optimize public financial resources by avoiding hemodialysis and consequently kidney transplantation.