Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | The Journal of venomous animals and toxins including tropical diseases (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200007 |
Resumo: | Extracted venoms from two species of cubozoan, Chironex fleckeri (C. fleckeri)and Chiropsalmus sp., were injected into the freshwater crayfish Cherax quadricarinatus (C. quadricarinatus). By means of a Vascular Doppler, the cardiac parameters heart rate and contraction amplitude were recorded, with the theoretical total heart output calculated from these two recordings. Cherax quadricarinatus reflects prey items utilized by these two species in the wild and so comparisons of venom action on this animal have greater ecological relevance than those of previous mammalian models used. While the results of this study reflect previous research showing that the overall potency of C. fleckeri venom is greater than that of Chiropsalmus sp. venom, the action of the venoms on the heart muscle is found to be different. Chironex fleckeri,which has the most potent venom out of these two species, is actually less effective in reducing cardiac activity than Chiropsalmus sp., which may be a direct reflection of the variation in primary prey utilized by each species. |
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The Journal of venomous animals and toxins including tropical diseases (Online) |
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Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate modelcubozoanvenomcardiac functionCherax quadricarinatusChironex fleckeriChiropsalmus spExtracted venoms from two species of cubozoan, Chironex fleckeri (C. fleckeri)and Chiropsalmus sp., were injected into the freshwater crayfish Cherax quadricarinatus (C. quadricarinatus). By means of a Vascular Doppler, the cardiac parameters heart rate and contraction amplitude were recorded, with the theoretical total heart output calculated from these two recordings. Cherax quadricarinatus reflects prey items utilized by these two species in the wild and so comparisons of venom action on this animal have greater ecological relevance than those of previous mammalian models used. While the results of this study reflect previous research showing that the overall potency of C. fleckeri venom is greater than that of Chiropsalmus sp. venom, the action of the venoms on the heart muscle is found to be different. Chironex fleckeri,which has the most potent venom out of these two species, is actually less effective in reducing cardiac activity than Chiropsalmus sp., which may be a direct reflection of the variation in primary prey utilized by each species.Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)2006-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200007Journal of Venomous Animals and Toxins including Tropical Diseases v.12 n.2 2006reponame:The Journal of venomous animals and toxins including tropical diseases (Online)instname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/S1678-91992006000200007info:eu-repo/semantics/openAccessCarrette,T.Seymour,J.eng2006-06-26T00:00:00Zoai:scielo:S1678-91992006000200007Revistahttp://www.scielo.br/jvatitdPUBhttps://old.scielo.br/oai/scielo-oai.php||editorial@jvat.org.br1678-91991678-9180opendoar:2006-06-26T00:00The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
title |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
spellingShingle |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model Carrette,T. cubozoan venom cardiac function Cherax quadricarinatus Chironex fleckeri Chiropsalmus sp |
title_short |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
title_full |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
title_fullStr |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
title_full_unstemmed |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
title_sort |
Cardiotoxic effects of venoms from Chironex fleckeri and Chiropsalmus sp. on an invertebrate model |
author |
Carrette,T. |
author_facet |
Carrette,T. Seymour,J. |
author_role |
author |
author2 |
Seymour,J. |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Carrette,T. Seymour,J. |
dc.subject.por.fl_str_mv |
cubozoan venom cardiac function Cherax quadricarinatus Chironex fleckeri Chiropsalmus sp |
topic |
cubozoan venom cardiac function Cherax quadricarinatus Chironex fleckeri Chiropsalmus sp |
description |
Extracted venoms from two species of cubozoan, Chironex fleckeri (C. fleckeri)and Chiropsalmus sp., were injected into the freshwater crayfish Cherax quadricarinatus (C. quadricarinatus). By means of a Vascular Doppler, the cardiac parameters heart rate and contraction amplitude were recorded, with the theoretical total heart output calculated from these two recordings. Cherax quadricarinatus reflects prey items utilized by these two species in the wild and so comparisons of venom action on this animal have greater ecological relevance than those of previous mammalian models used. While the results of this study reflect previous research showing that the overall potency of C. fleckeri venom is greater than that of Chiropsalmus sp. venom, the action of the venoms on the heart muscle is found to be different. Chironex fleckeri,which has the most potent venom out of these two species, is actually less effective in reducing cardiac activity than Chiropsalmus sp., which may be a direct reflection of the variation in primary prey utilized by each species. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992006000200007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1678-91992006000200007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) |
publisher.none.fl_str_mv |
Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) |
dc.source.none.fl_str_mv |
Journal of Venomous Animals and Toxins including Tropical Diseases v.12 n.2 2006 reponame:The Journal of venomous animals and toxins including tropical diseases (Online) instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
The Journal of venomous animals and toxins including tropical diseases (Online) |
collection |
The Journal of venomous animals and toxins including tropical diseases (Online) |
repository.name.fl_str_mv |
The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
||editorial@jvat.org.br |
_version_ |
1748958537890922496 |