Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation

Detalhes bibliográficos
Autor(a) principal: Carvalho,FR
Data de Publicação: 2010
Outros Autores: Vassão,RC, Nicoletti,MA, Maria,DA
Tipo de documento: Artigo
Idioma: eng
Título da fonte: The Journal of venomous animals and toxins including tropical diseases (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200013
Resumo: The aim of the present work was to study the effect of the crude extract of Curcuma zedoaria on peripheral blood cells and tumor progression in C57Bl/6J mice injected with B16F10 murine melanoma cells. The intraperitoneal therapy showed a significant increase in total white and red blood cell counts, a decrease in peritoneal cell number and tumor volume reduction, whereas the oral administration revealed a noteworthy augmentation only in total leukocyte count. These results contribute to evaluate the importance of alternative treatments that employ phytotherapic compounds against tumor progression and its possible immunomodulation.
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spelling Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulationmelanomatumorhematologyCurcuma zedoariaThe aim of the present work was to study the effect of the crude extract of Curcuma zedoaria on peripheral blood cells and tumor progression in C57Bl/6J mice injected with B16F10 murine melanoma cells. The intraperitoneal therapy showed a significant increase in total white and red blood cell counts, a decrease in peritoneal cell number and tumor volume reduction, whereas the oral administration revealed a noteworthy augmentation only in total leukocyte count. These results contribute to evaluate the importance of alternative treatments that employ phytotherapic compounds against tumor progression and its possible immunomodulation.Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200013Journal of Venomous Animals and Toxins including Tropical Diseases v.16 n.2 2010reponame:The Journal of venomous animals and toxins including tropical diseases (Online)instname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/S1678-91992010000200013info:eu-repo/semantics/openAccessCarvalho,FRVassão,RCNicoletti,MAMaria,DAeng2010-06-07T00:00:00Zoai:scielo:S1678-91992010000200013Revistahttp://www.scielo.br/jvatitdPUBhttps://old.scielo.br/oai/scielo-oai.php||editorial@jvat.org.br1678-91991678-9180opendoar:2010-06-07T00:00The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
title Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
spellingShingle Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
Carvalho,FR
melanoma
tumor
hematology
Curcuma zedoaria
title_short Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
title_full Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
title_fullStr Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
title_full_unstemmed Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
title_sort Effect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
author Carvalho,FR
author_facet Carvalho,FR
Vassão,RC
Nicoletti,MA
Maria,DA
author_role author
author2 Vassão,RC
Nicoletti,MA
Maria,DA
author2_role author
author
author
dc.contributor.author.fl_str_mv Carvalho,FR
Vassão,RC
Nicoletti,MA
Maria,DA
dc.subject.por.fl_str_mv melanoma
tumor
hematology
Curcuma zedoaria
topic melanoma
tumor
hematology
Curcuma zedoaria
description The aim of the present work was to study the effect of the crude extract of Curcuma zedoaria on peripheral blood cells and tumor progression in C57Bl/6J mice injected with B16F10 murine melanoma cells. The intraperitoneal therapy showed a significant increase in total white and red blood cell counts, a decrease in peritoneal cell number and tumor volume reduction, whereas the oral administration revealed a noteworthy augmentation only in total leukocyte count. These results contribute to evaluate the importance of alternative treatments that employ phytotherapic compounds against tumor progression and its possible immunomodulation.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200013
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992010000200013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1678-91992010000200013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP)
dc.source.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases v.16 n.2 2010
reponame:The Journal of venomous animals and toxins including tropical diseases (Online)
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str The Journal of venomous animals and toxins including tropical diseases (Online)
collection The Journal of venomous animals and toxins including tropical diseases (Online)
repository.name.fl_str_mv The Journal of venomous animals and toxins including tropical diseases (Online) - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv ||editorial@jvat.org.br
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