Metabolic profile of diabetic rats submitted to chronic physical exercise

Detalhes bibliográficos
Autor(a) principal: Elizeu da Silva, Kelly
Data de Publicação: 2007
Outros Autores: Gomes, Ricardo José, Hermini, Helton André, Moreira de Azevedo, José Roberto, Luciano, Eliete
Tipo de documento: Artigo
Idioma: por
Título da fonte: Motriz (Online)
Texto Completo: https://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/388
Resumo: The aim of the present study was to examine the effects of physical exercise on the metabolic profile in diabetic rats induced by streptozotocin. Male Wistar rats were divided into 4 groups, sedentary control (SC), trained control (TC), sedentary diabetic (SD) and trained diabetic (TD). Diabetes was induced by Streptozotocin (50 mg/kg b.w. i.v.). The training program consisted of swimming 5 days/week, 1 h/day, supporting a load of 5 % body weight for 8 weeks. The diabetic groups (sedentary and trained) showed hyperglycemia. The training reduced serum AGL in both, diabetic and control groups. Besides, the training increased total proteins and muscle glycogen in control group. It was concluded that diabetes (by streptozotocin) induced some alterations on metabolic profile and physical training promoted important metabolic adaptations in Wistar rats.
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spelling Metabolic profile of diabetic rats submitted to chronic physical exercisePerfil metabólico de ratos diabéticos submetidos ao exercício físico crônicoDiabetesmetabolismoexercício crônicoestreptozotocina.The aim of the present study was to examine the effects of physical exercise on the metabolic profile in diabetic rats induced by streptozotocin. Male Wistar rats were divided into 4 groups, sedentary control (SC), trained control (TC), sedentary diabetic (SD) and trained diabetic (TD). Diabetes was induced by Streptozotocin (50 mg/kg b.w. i.v.). The training program consisted of swimming 5 days/week, 1 h/day, supporting a load of 5 % body weight for 8 weeks. The diabetic groups (sedentary and trained) showed hyperglycemia. The training reduced serum AGL in both, diabetic and control groups. Besides, the training increased total proteins and muscle glycogen in control group. It was concluded that diabetes (by streptozotocin) induced some alterations on metabolic profile and physical training promoted important metabolic adaptations in Wistar rats.O objetivo deste estudo foi investigar os efeitos do exercício físico crônico sobre o perfil metabólico de ratos diabéticos induzidos por estreptozotocina. Ratos Wistar foram distribuídos nos seguintes grupos: Controle Sedentário (CS), Controle Treinado (CT), Diabético Sedentário (DS) e Diabético Treinado (DT). O diabetes foi induzido por estreptozotocina (50mg/kg pc. i.v.). O programa de treinamento consistiu de uma hora de natação diária, cinco dias/semana, durante oito semanas consecutivas com 5% de sobrecarga. Os ratos diabéticos sedentários e treinados apresentaram elevada glicemia. O treinamento físico reduziu as concentrações séricas de AGL nos grupos diabético e controle. Além disso, as proteínas totais bem como o glicogênio do músculo foram aumentados pelo exercício crônico no grupo controle. Concluímos que o diabetes induzido por estreptozotocina, altera o perfil metabólico, enquanto o exercício físico crônico promove algumas importantes adaptações metabólicas em ratos Wistar.Universidade Estadual Paulista - Câmpus de Rio Claro2007-06-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionDocumento Avaliado por Paresapplication/pdfhttps://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/38810.5016/388Motriz. Journal of Physical Education. UNESP; V. 10, N. 3 (2004); 189-193Motriz Revista de Educação Física; V. 10, N. 3 (2004); 189-1931980-6574reponame:Motriz (Online)instname:Universidade Estadual Paulista (UNESP)instacron:UNESPporhttps://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/388/334Elizeu da Silva, KellyGomes, Ricardo JoséHermini, Helton AndréMoreira de Azevedo, José RobertoLuciano, Elieteinfo:eu-repo/semantics/openAccess2007-06-19T14:54:29Zoai:periodicos.rc.biblioteca.unesp.br:article/388Revistahttp://www.periodicos.rc.biblioteca.unesp.br/index.php/motrizPUBhttps://old.scielo.br/oai/scielo-oai.phpmotriz@rc.unesp.br||mauerber@rc.unesp.br||azanesco@rc.unesp.br1980-65741415-9805opendoar:2007-06-19T14:54:29Motriz (Online) - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Metabolic profile of diabetic rats submitted to chronic physical exercise
Perfil metabólico de ratos diabéticos submetidos ao exercício físico crônico
title Metabolic profile of diabetic rats submitted to chronic physical exercise
spellingShingle Metabolic profile of diabetic rats submitted to chronic physical exercise
Elizeu da Silva, Kelly
Diabetes
metabolismo
exercício crônico
estreptozotocina.
title_short Metabolic profile of diabetic rats submitted to chronic physical exercise
title_full Metabolic profile of diabetic rats submitted to chronic physical exercise
title_fullStr Metabolic profile of diabetic rats submitted to chronic physical exercise
title_full_unstemmed Metabolic profile of diabetic rats submitted to chronic physical exercise
title_sort Metabolic profile of diabetic rats submitted to chronic physical exercise
author Elizeu da Silva, Kelly
author_facet Elizeu da Silva, Kelly
Gomes, Ricardo José
Hermini, Helton André
Moreira de Azevedo, José Roberto
Luciano, Eliete
author_role author
author2 Gomes, Ricardo José
Hermini, Helton André
Moreira de Azevedo, José Roberto
Luciano, Eliete
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Elizeu da Silva, Kelly
Gomes, Ricardo José
Hermini, Helton André
Moreira de Azevedo, José Roberto
Luciano, Eliete
dc.subject.por.fl_str_mv Diabetes
metabolismo
exercício crônico
estreptozotocina.
topic Diabetes
metabolismo
exercício crônico
estreptozotocina.
description The aim of the present study was to examine the effects of physical exercise on the metabolic profile in diabetic rats induced by streptozotocin. Male Wistar rats were divided into 4 groups, sedentary control (SC), trained control (TC), sedentary diabetic (SD) and trained diabetic (TD). Diabetes was induced by Streptozotocin (50 mg/kg b.w. i.v.). The training program consisted of swimming 5 days/week, 1 h/day, supporting a load of 5 % body weight for 8 weeks. The diabetic groups (sedentary and trained) showed hyperglycemia. The training reduced serum AGL in both, diabetic and control groups. Besides, the training increased total proteins and muscle glycogen in control group. It was concluded that diabetes (by streptozotocin) induced some alterations on metabolic profile and physical training promoted important metabolic adaptations in Wistar rats.
publishDate 2007
dc.date.none.fl_str_mv 2007-06-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Documento Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/388
10.5016/388
url https://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/388
identifier_str_mv 10.5016/388
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.periodicos.rc.biblioteca.unesp.br/index.php/motriz/article/view/388/334
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual Paulista - Câmpus de Rio Claro
publisher.none.fl_str_mv Universidade Estadual Paulista - Câmpus de Rio Claro
dc.source.none.fl_str_mv Motriz. Journal of Physical Education. UNESP; V. 10, N. 3 (2004); 189-193
Motriz Revista de Educação Física; V. 10, N. 3 (2004); 189-193
1980-6574
reponame:Motriz (Online)
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Motriz (Online)
collection Motriz (Online)
repository.name.fl_str_mv Motriz (Online) - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv motriz@rc.unesp.br||mauerber@rc.unesp.br||azanesco@rc.unesp.br
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