Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Dental Science |
Texto Completo: | https://ojs.ict.unesp.br/index.php/cob/article/view/998 |
Resumo: | Objective: The aim of this study was to evaluate the effectiveness of platelet rich plasma with and without autogenous bone graft in the bone repair of surgical defects in rabbit tibias. Materials and Methods: In this research, 25 adult male rabbits were used. Two defects have been performed in each tibia, divided into four groups: control (C = defect naturally left to heal by clot formation), autogenous (A = bone defect + autogenous graft), PRP (PRP = bone defect + PRP) and autogenous + PRP (PRPA = bone defect + autogenous graft + PRP). All the defects were covered with a dPTFE membrane. Five other animals were sacrificed at 15, 30, and 60-day postoperatively. The pieces containing the defects were processed for histological and histomorphometric analysis. Other five animals were sacrificed after 30 and 60 days and submitted to biomechanical analysis, and all the specimens were sent to the radiographic evaluation of optical density. Results: The biomechanical, radiographic, and histomorphometric results showed larger resistance, optical density, and improving bone formation in the groups A and PRPA when compared with the groups C and PRP. Conclusion: This study showed there was not an improvement in the radiographic, mechanical, and bone formation parameters when PRP was used individually or associated to the autogenous bone graft. |
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Brazilian Dental Science |
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Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graftObjective: The aim of this study was to evaluate the effectiveness of platelet rich plasma with and without autogenous bone graft in the bone repair of surgical defects in rabbit tibias. Materials and Methods: In this research, 25 adult male rabbits were used. Two defects have been performed in each tibia, divided into four groups: control (C = defect naturally left to heal by clot formation), autogenous (A = bone defect + autogenous graft), PRP (PRP = bone defect + PRP) and autogenous + PRP (PRPA = bone defect + autogenous graft + PRP). All the defects were covered with a dPTFE membrane. Five other animals were sacrificed at 15, 30, and 60-day postoperatively. The pieces containing the defects were processed for histological and histomorphometric analysis. Other five animals were sacrificed after 30 and 60 days and submitted to biomechanical analysis, and all the specimens were sent to the radiographic evaluation of optical density. Results: The biomechanical, radiographic, and histomorphometric results showed larger resistance, optical density, and improving bone formation in the groups A and PRPA when compared with the groups C and PRP. Conclusion: This study showed there was not an improvement in the radiographic, mechanical, and bone formation parameters when PRP was used individually or associated to the autogenous bone graft.Institute of Science and Technology of São José dos Campos2014-11-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/mswordimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpeghttps://ojs.ict.unesp.br/index.php/cob/article/view/99810.14295/bds.2014.v17i4.998Brazilian Dental Science; Vol. 17 No. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 53-64Brazilian Dental Science; v. 17 n. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 53-642178-6011reponame:Brazilian Dental Scienceinstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESPenghttps://ojs.ict.unesp.br/index.php/cob/article/view/998/899https://ojs.ict.unesp.br/index.php/cob/article/view/998/2088https://ojs.ict.unesp.br/index.php/cob/article/view/998/2089https://ojs.ict.unesp.br/index.php/cob/article/view/998/2090https://ojs.ict.unesp.br/index.php/cob/article/view/998/2091https://ojs.ict.unesp.br/index.php/cob/article/view/998/2092https://ojs.ict.unesp.br/index.php/cob/article/view/998/2093https://ojs.ict.unesp.br/index.php/cob/article/view/998/2094https://ojs.ict.unesp.br/index.php/cob/article/view/998/2095https://ojs.ict.unesp.br/index.php/cob/article/view/998/2096https://ojs.ict.unesp.br/index.php/cob/article/view/998/2097Monteiro, Adriana Socorro FerreiraMacedo, Nelson LuizMacedo, Luiz Guilherme ScavoneRocha, Rosilene Fernandesinfo:eu-repo/semantics/openAccess2020-01-28T12:30:28Zoai:ojs.pkp.sfu.ca:article/998Revistahttp://bds.ict.unesp.br/PUBhttp://ojs.fosjc.unesp.br/index.php/index/oaisergio@fosjc.unesp.br||sergio@fosjc.unesp.br2178-60112178-6011opendoar:2022-11-08T16:29:57.333799Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)true |
dc.title.none.fl_str_mv |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
title |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
spellingShingle |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft Monteiro, Adriana Socorro Ferreira |
title_short |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
title_full |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
title_fullStr |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
title_full_unstemmed |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
title_sort |
Histomorphometric, radiographic and biomechanical analyses of platelet rich plasma associated with autogenous bone graft |
author |
Monteiro, Adriana Socorro Ferreira |
author_facet |
Monteiro, Adriana Socorro Ferreira Macedo, Nelson Luiz Macedo, Luiz Guilherme Scavone Rocha, Rosilene Fernandes |
author_role |
author |
author2 |
Macedo, Nelson Luiz Macedo, Luiz Guilherme Scavone Rocha, Rosilene Fernandes |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Monteiro, Adriana Socorro Ferreira Macedo, Nelson Luiz Macedo, Luiz Guilherme Scavone Rocha, Rosilene Fernandes |
description |
Objective: The aim of this study was to evaluate the effectiveness of platelet rich plasma with and without autogenous bone graft in the bone repair of surgical defects in rabbit tibias. Materials and Methods: In this research, 25 adult male rabbits were used. Two defects have been performed in each tibia, divided into four groups: control (C = defect naturally left to heal by clot formation), autogenous (A = bone defect + autogenous graft), PRP (PRP = bone defect + PRP) and autogenous + PRP (PRPA = bone defect + autogenous graft + PRP). All the defects were covered with a dPTFE membrane. Five other animals were sacrificed at 15, 30, and 60-day postoperatively. The pieces containing the defects were processed for histological and histomorphometric analysis. Other five animals were sacrificed after 30 and 60 days and submitted to biomechanical analysis, and all the specimens were sent to the radiographic evaluation of optical density. Results: The biomechanical, radiographic, and histomorphometric results showed larger resistance, optical density, and improving bone formation in the groups A and PRPA when compared with the groups C and PRP. Conclusion: This study showed there was not an improvement in the radiographic, mechanical, and bone formation parameters when PRP was used individually or associated to the autogenous bone graft. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-11-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/998 10.14295/bds.2014.v17i4.998 |
url |
https://ojs.ict.unesp.br/index.php/cob/article/view/998 |
identifier_str_mv |
10.14295/bds.2014.v17i4.998 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.ict.unesp.br/index.php/cob/article/view/998/899 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2088 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2089 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2090 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2091 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2092 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2093 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2094 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2095 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2096 https://ojs.ict.unesp.br/index.php/cob/article/view/998/2097 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/msword image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg image/jpeg |
dc.publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
publisher.none.fl_str_mv |
Institute of Science and Technology of São José dos Campos |
dc.source.none.fl_str_mv |
Brazilian Dental Science; Vol. 17 No. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 53-64 Brazilian Dental Science; v. 17 n. 4 (2014): Oct. - Dec. / 2014 - Published November 2014; 53-64 2178-6011 reponame:Brazilian Dental Science instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Brazilian Dental Science |
collection |
Brazilian Dental Science |
repository.name.fl_str_mv |
Brazilian Dental Science - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
repository.mail.fl_str_mv |
sergio@fosjc.unesp.br||sergio@fosjc.unesp.br |
_version_ |
1788346898971623424 |