Spectrophotometric determination of mosapride in pure and pharmaceutical preparations

Detalhes bibliográficos
Autor(a) principal: Revanasiddappa,H. D.
Data de Publicação: 2007
Outros Autores: Veena,M. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Eclética Química
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702007000400010
Resumo: Two simple and sensitive spectrophotometric methods (M1 and M2) for the determination of mosapride in pure and in pharmaceutical preparations are described. These methods are based on the interaction of diazotized mosapride (MSP) couples with chromotropic acid (CTA) [M1] in alkaline medium and diphenylamine (DPA) [M2] in acidic medium. The resulting azo-dyes exhibit maximum absorption at 560 nm and at 540 nm for methods M1 and M2, respectively. All variables were studied in order to optimize the reaction conditions. No interferences were observed from excipients, and the validity of the each method was tested against reference method.
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spelling Spectrophotometric determination of mosapride in pure and pharmaceutical preparationsmosapridechromotropic aciddiphenylaminespectrophotometrypharmaceutical analysisTwo simple and sensitive spectrophotometric methods (M1 and M2) for the determination of mosapride in pure and in pharmaceutical preparations are described. These methods are based on the interaction of diazotized mosapride (MSP) couples with chromotropic acid (CTA) [M1] in alkaline medium and diphenylamine (DPA) [M2] in acidic medium. The resulting azo-dyes exhibit maximum absorption at 560 nm and at 540 nm for methods M1 and M2, respectively. All variables were studied in order to optimize the reaction conditions. No interferences were observed from excipients, and the validity of the each method was tested against reference method.Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP2007-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702007000400010Eclética Química v.32 n.4 2007reponame:Eclética Químicainstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESP10.1590/S0100-46702007000400010info:eu-repo/semantics/openAccessRevanasiddappa,H. D.Veena,M. A.eng2008-01-30T00:00:00Zoai:scielo:S0100-46702007000400010Revistahttp://revista.iq.unesp.br/ojs/index.php/ecletica/PUBhttps://revista.iq.unesp.br/ojs/index.php/ecletica/oaiecletica@ctrlk.com.br||ecletica@iq.unesp.br1678-46181678-4618opendoar:2008-01-30T00:00Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)false
dc.title.none.fl_str_mv Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
title Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
spellingShingle Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
Revanasiddappa,H. D.
mosapride
chromotropic acid
diphenylamine
spectrophotometry
pharmaceutical analysis
title_short Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
title_full Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
title_fullStr Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
title_full_unstemmed Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
title_sort Spectrophotometric determination of mosapride in pure and pharmaceutical preparations
author Revanasiddappa,H. D.
author_facet Revanasiddappa,H. D.
Veena,M. A.
author_role author
author2 Veena,M. A.
author2_role author
dc.contributor.author.fl_str_mv Revanasiddappa,H. D.
Veena,M. A.
dc.subject.por.fl_str_mv mosapride
chromotropic acid
diphenylamine
spectrophotometry
pharmaceutical analysis
topic mosapride
chromotropic acid
diphenylamine
spectrophotometry
pharmaceutical analysis
description Two simple and sensitive spectrophotometric methods (M1 and M2) for the determination of mosapride in pure and in pharmaceutical preparations are described. These methods are based on the interaction of diazotized mosapride (MSP) couples with chromotropic acid (CTA) [M1] in alkaline medium and diphenylamine (DPA) [M2] in acidic medium. The resulting azo-dyes exhibit maximum absorption at 560 nm and at 540 nm for methods M1 and M2, respectively. All variables were studied in order to optimize the reaction conditions. No interferences were observed from excipients, and the validity of the each method was tested against reference method.
publishDate 2007
dc.date.none.fl_str_mv 2007-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702007000400010
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702007000400010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-46702007000400010
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
dc.source.none.fl_str_mv Eclética Química v.32 n.4 2007
reponame:Eclética Química
instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Eclética Química
collection Eclética Química
repository.name.fl_str_mv Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
repository.mail.fl_str_mv ecletica@ctrlk.com.br||ecletica@iq.unesp.br
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