Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S

Detalhes bibliográficos
Autor(a) principal: Fatibello-Filho,Orlando
Data de Publicação: 2009
Outros Autores: Vieira,Heberth Juliano
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Eclética Química
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008
Resumo: A spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level.
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spelling Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red SFlow injection analysisZinc(II)Alizarin red Sspectrophotometryophthalmic formulationsA spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level.Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008Eclética Química v.34 n.2 2009reponame:Eclética Químicainstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESP10.1590/S0100-46702009000200008info:eu-repo/semantics/openAccessFatibello-Filho,OrlandoVieira,Heberth Julianoeng2010-02-08T00:00:00Zoai:scielo:S0100-46702009000200008Revistahttp://revista.iq.unesp.br/ojs/index.php/ecletica/PUBhttps://revista.iq.unesp.br/ojs/index.php/ecletica/oaiecletica@ctrlk.com.br||ecletica@iq.unesp.br1678-46181678-4618opendoar:2010-02-08T00:00Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)false
dc.title.none.fl_str_mv Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
title Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
spellingShingle Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
Fatibello-Filho,Orlando
Flow injection analysis
Zinc(II)
Alizarin red S
spectrophotometry
ophthalmic formulations
title_short Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
title_full Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
title_fullStr Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
title_full_unstemmed Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
title_sort Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
author Fatibello-Filho,Orlando
author_facet Fatibello-Filho,Orlando
Vieira,Heberth Juliano
author_role author
author2 Vieira,Heberth Juliano
author2_role author
dc.contributor.author.fl_str_mv Fatibello-Filho,Orlando
Vieira,Heberth Juliano
dc.subject.por.fl_str_mv Flow injection analysis
Zinc(II)
Alizarin red S
spectrophotometry
ophthalmic formulations
topic Flow injection analysis
Zinc(II)
Alizarin red S
spectrophotometry
ophthalmic formulations
description A spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level.
publishDate 2009
dc.date.none.fl_str_mv 2009-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-46702009000200008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
publisher.none.fl_str_mv Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP
dc.source.none.fl_str_mv Eclética Química v.34 n.2 2009
reponame:Eclética Química
instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Eclética Química
collection Eclética Química
repository.name.fl_str_mv Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)
repository.mail.fl_str_mv ecletica@ctrlk.com.br||ecletica@iq.unesp.br
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