Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Eclética Química |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008 |
Resumo: | A spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level. |
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UNESP-29 |
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Eclética Química |
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spelling |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red SFlow injection analysisZinc(II)Alizarin red Sspectrophotometryophthalmic formulationsA spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level.Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008Eclética Química v.34 n.2 2009reponame:Eclética Químicainstname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)instacron:UNESP10.1590/S0100-46702009000200008info:eu-repo/semantics/openAccessFatibello-Filho,OrlandoVieira,Heberth Julianoeng2010-02-08T00:00:00Zoai:scielo:S0100-46702009000200008Revistahttp://revista.iq.unesp.br/ojs/index.php/ecletica/PUBhttps://revista.iq.unesp.br/ojs/index.php/ecletica/oaiecletica@ctrlk.com.br||ecletica@iq.unesp.br1678-46181678-4618opendoar:2010-02-08T00:00Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)false |
dc.title.none.fl_str_mv |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
title |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
spellingShingle |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S Fatibello-Filho,Orlando Flow injection analysis Zinc(II) Alizarin red S spectrophotometry ophthalmic formulations |
title_short |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
title_full |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
title_fullStr |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
title_full_unstemmed |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
title_sort |
Spectrophotometric flow injection system for determination of Zn2+ in ophthalmic formulations using Alizarin red S |
author |
Fatibello-Filho,Orlando |
author_facet |
Fatibello-Filho,Orlando Vieira,Heberth Juliano |
author_role |
author |
author2 |
Vieira,Heberth Juliano |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Fatibello-Filho,Orlando Vieira,Heberth Juliano |
dc.subject.por.fl_str_mv |
Flow injection analysis Zinc(II) Alizarin red S spectrophotometry ophthalmic formulations |
topic |
Flow injection analysis Zinc(II) Alizarin red S spectrophotometry ophthalmic formulations |
description |
A spectrophotometric flow injection method for the determination of Zn(II) in ophthalmic formulations was developed. In this work, Zn(II) ion was complexed with Alizarin red S in borate buffer solution (pH 9.0) and the chromophore produced was monitored at 520 nm. The analytical curve was linear in the Zn(II) concentration range from 6.05 x 10-6 to 1.50 x 10-4 mol L-1 with a detection limit of 3.60 x 10-6 mol L-1. Recoveries ranged from 96.3 to 105 % and a relative standard deviation of 1.2 % (n = 10) for 5.5x10-5 mol L-1 Zn(II) reference solution were obtained. The sampling rate was 60 h-1 and the results obtained of Zn(II) in ophthalmic products using this procedure are in close agreement with those obtained using a comparative spectrophotometric procedure at 95 % confidence level. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-46702009000200008 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-46702009000200008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP |
publisher.none.fl_str_mv |
Fundação Editora da Universidade Estadual Paulista Júlio de Mesquita Filho - UNESP |
dc.source.none.fl_str_mv |
Eclética Química v.34 n.2 2009 reponame:Eclética Química instname:Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Eclética Química |
collection |
Eclética Química |
repository.name.fl_str_mv |
Eclética Química - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP) |
repository.mail.fl_str_mv |
ecletica@ctrlk.com.br||ecletica@iq.unesp.br |
_version_ |
1754734618538409984 |