Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae)
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Revista Brasileira Multidisciplinar |
| Texto Completo: | http://revistarebram.com/index.php/revistauniara/article/view/1296 |
Resumo: | This research determined the phytochemical profile and evaluated the photoprotective, antimicrobial and antioxidant activities in extracts of Clidemia capitellata leaves, obtained with hexane, ethyl acetate and methanol. The phytochemical profile was determined through thin layer chromatography; tannins, flavonoids and total phenolics were measured; the antimicrobial activity was determined by Minimum Inhibitory Concentration and Minimum Microbicide Concentration in bacteria Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis and Enterococcus faecalis; Escherichia coli, Serratia marcescens and Pseudomonas aeruginosa, Mycobacterium smegmatis, and the yeast Candida albicans. Antioxidant activity was evaluated through the methods of Reducing Power, DPPH sequestration and phosphomolybdenum. The C. capitellata leaves show flavonoids, tannins, triterpenes, steroids, anthraquinones and essential oils; tannins, flavonoids and total phenolics were extracted in greater amounts with methanol, however, the acetate extract stood out in relation to antimicrobial activity, and none of the extracts showed photoprotective activity within the values established by Brazilian legislation. Word keys: secondary metabolites. antioxidant. antimicrobial. |
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Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae)Phytochemical analysis and biological activity from clidemia capitellata leaves (melastomataceae)secondary metabolites. antioxidant. antimicrobial.metabolitos secundarios. antioxidante. antimicrobiano.metabólitos secundários. antioxidante. antimicrobiano.This research determined the phytochemical profile and evaluated the photoprotective, antimicrobial and antioxidant activities in extracts of Clidemia capitellata leaves, obtained with hexane, ethyl acetate and methanol. The phytochemical profile was determined through thin layer chromatography; tannins, flavonoids and total phenolics were measured; the antimicrobial activity was determined by Minimum Inhibitory Concentration and Minimum Microbicide Concentration in bacteria Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis and Enterococcus faecalis; Escherichia coli, Serratia marcescens and Pseudomonas aeruginosa, Mycobacterium smegmatis, and the yeast Candida albicans. Antioxidant activity was evaluated through the methods of Reducing Power, DPPH sequestration and phosphomolybdenum. The C. capitellata leaves show flavonoids, tannins, triterpenes, steroids, anthraquinones and essential oils; tannins, flavonoids and total phenolics were extracted in greater amounts with methanol, however, the acetate extract stood out in relation to antimicrobial activity, and none of the extracts showed photoprotective activity within the values established by Brazilian legislation. Word keys: secondary metabolites. antioxidant. antimicrobial.Esta investigación determinó el perfil fitoquímico y evaluó las actividades fotoprotectoras, antimicrobianas y antioxidantes en extractos de hojas de Clidemia capitellata, obtenidos con hexano, etilo y metanol. El perfil fitoquímico se determinó mediante cromatografía en capa fina; se midieron taninos, flavonoides y fenoles totales; la actividad antimicrobiana se determinó mediante Concentración Mínima Inhibidora y Concentración Mínima de Microbicida en bacterias Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis y Enterococcus faecalis; Escherichia coli, Serratia marcescens y Pseudomonas aeruginosa, Mycobacterium smegmatis y la levadura Candida albicans. La actividad antioxidante se evaluó mediante los métodos de Poder Reductor, secuestro de DPPH y fosfomolibdeno. Las hojas de C. capitellata presentan flavonoides, taninos, triterpenos, esteroides, antraquinonas y aceites esenciales; los taninos, flavonoides y fenoles totales se extrajeron en mayor cantidad con metanol, sin embargo, el extracto se destacó en relación a la actividad antimicrobiana, y ninguno de los extractos mostró actividad fotoprotectora dentro de los valores establecidos por la legislación brasileña. Palabras llaves: metabolitos secundarios. antioxidante. antimicrobiano.Esta pesquisa determinou o perfil fitoquímico e avaliou as atividades fotoprotetora, antimicrobiana e antioxidante de extratos de folhas de Clidemia capitellata, obtidos com hexano, acetato de etila e metanol. Cromatografia em camada delgada foi usada para identificação dos metabólitos; taninos, flavonóides e fenólicos totais foram medidos; a atividade antimicrobiana foi determinada pela Concentração Inibitória Mínima e Concentração Microbicida Mínima nas bactérias Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis e Enterococcus faecalis; Escherichia coli, Serratia marcescens e Pseudomonas aeruginosa, Mycobacterium smegmatis e a levedura Candida albicans. A atividade antioxidante foi avaliada através dos métodos de Poder Redutor, sequestro de DPPH e fosfomolibdênio. As folhas de C. capitellata apresentam flavonóides, taninos, triterpenos, esteróides, antraquinonas e óleos essenciais; taninos, flavonóides e fenólicos totais foram extraídos em maiores quantidades com metanol, porém, o extrato acetato se destacou em relação à atividade antimicrobiana, e nenhum dos extratos apresentou atividade fotoprotetora dentro dos valores estabelecidos pela legislação brasileira. Palavras-chave: metabólitos secundários. antioxidante. antimicrobiano.Revista Brasileira Multidisciplinar - ReBraM2022-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://revistarebram.com/index.php/revistauniara/article/view/129610.25061/2527-2675/ReBraM/2022.v25i3.1296Revista Brasileira Multidisciplinar; v. 25 n. 3 (2022): Setembro-Dezembro; 62-722527-26751415-3580reponame:Revista Brasileira Multidisciplinarinstname:Universidade de Araraquara (UNIARA)instacron:UNIARAporhttp://revistarebram.com/index.php/revistauniara/article/view/1296/871Copyright (c) 2022 Revista Brasileira Multidisciplinar - ReBraMhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessVitória Ferreira da Silva, Acsa Henrique Silva dos Santos, Rodrigo Anderson de Morais, Bruno Isabela Ferreira de Araújo, Maria Barbosa, Paula Perazzo de SouzaFernanda de Oliveira Borba, Elizabeth Reges de Sena, Amanda Cley Campos Leite, Tonny2023-03-23T23:25:54Zoai:ojs.revistarebram.com:article/1296Revistahttp://revistarebram.com/index.php/revistauniaraPRIhttps://revistarebram.com/index.php/revistauniara/oairevistauniara@uniara.com||2527-26752527-2675opendoar:2023-03-23T23:25:54Revista Brasileira Multidisciplinar - Universidade de Araraquara (UNIARA)false |
| dc.title.none.fl_str_mv |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) Phytochemical analysis and biological activity from clidemia capitellata leaves (melastomataceae) |
| title |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| spellingShingle |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) Vitória Ferreira da Silva, Acsa secondary metabolites. antioxidant. antimicrobial. metabolitos secundarios. antioxidante. antimicrobiano. metabólitos secundários. antioxidante. antimicrobiano. |
| title_short |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| title_full |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| title_fullStr |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| title_full_unstemmed |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| title_sort |
Phytochemical Analysis and Biological Activity from Clidemia capitellata leaves (Melastomataceae) |
| author |
Vitória Ferreira da Silva, Acsa |
| author_facet |
Vitória Ferreira da Silva, Acsa Henrique Silva dos Santos, Rodrigo Anderson de Morais, Bruno Isabela Ferreira de Araújo, Maria Barbosa, Paula Perazzo de Souza Fernanda de Oliveira Borba, Elizabeth Reges de Sena, Amanda Cley Campos Leite, Tonny |
| author_role |
author |
| author2 |
Henrique Silva dos Santos, Rodrigo Anderson de Morais, Bruno Isabela Ferreira de Araújo, Maria Barbosa, Paula Perazzo de Souza Fernanda de Oliveira Borba, Elizabeth Reges de Sena, Amanda Cley Campos Leite, Tonny |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Vitória Ferreira da Silva, Acsa Henrique Silva dos Santos, Rodrigo Anderson de Morais, Bruno Isabela Ferreira de Araújo, Maria Barbosa, Paula Perazzo de Souza Fernanda de Oliveira Borba, Elizabeth Reges de Sena, Amanda Cley Campos Leite, Tonny |
| dc.subject.por.fl_str_mv |
secondary metabolites. antioxidant. antimicrobial. metabolitos secundarios. antioxidante. antimicrobiano. metabólitos secundários. antioxidante. antimicrobiano. |
| topic |
secondary metabolites. antioxidant. antimicrobial. metabolitos secundarios. antioxidante. antimicrobiano. metabólitos secundários. antioxidante. antimicrobiano. |
| description |
This research determined the phytochemical profile and evaluated the photoprotective, antimicrobial and antioxidant activities in extracts of Clidemia capitellata leaves, obtained with hexane, ethyl acetate and methanol. The phytochemical profile was determined through thin layer chromatography; tannins, flavonoids and total phenolics were measured; the antimicrobial activity was determined by Minimum Inhibitory Concentration and Minimum Microbicide Concentration in bacteria Staphylococcus aureus, Micrococcus luteus, Bacillus subtilis and Enterococcus faecalis; Escherichia coli, Serratia marcescens and Pseudomonas aeruginosa, Mycobacterium smegmatis, and the yeast Candida albicans. Antioxidant activity was evaluated through the methods of Reducing Power, DPPH sequestration and phosphomolybdenum. The C. capitellata leaves show flavonoids, tannins, triterpenes, steroids, anthraquinones and essential oils; tannins, flavonoids and total phenolics were extracted in greater amounts with methanol, however, the acetate extract stood out in relation to antimicrobial activity, and none of the extracts showed photoprotective activity within the values established by Brazilian legislation. Word keys: secondary metabolites. antioxidant. antimicrobial. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-09-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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http://revistarebram.com/index.php/revistauniara/article/view/1296 10.25061/2527-2675/ReBraM/2022.v25i3.1296 |
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http://revistarebram.com/index.php/revistauniara/article/view/1296 |
| identifier_str_mv |
10.25061/2527-2675/ReBraM/2022.v25i3.1296 |
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por |
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por |
| dc.relation.none.fl_str_mv |
http://revistarebram.com/index.php/revistauniara/article/view/1296/871 |
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Copyright (c) 2022 Revista Brasileira Multidisciplinar - ReBraM https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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Copyright (c) 2022 Revista Brasileira Multidisciplinar - ReBraM https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Revista Brasileira Multidisciplinar - ReBraM |
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Revista Brasileira Multidisciplinar - ReBraM |
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Revista Brasileira Multidisciplinar; v. 25 n. 3 (2022): Setembro-Dezembro; 62-72 2527-2675 1415-3580 reponame:Revista Brasileira Multidisciplinar instname:Universidade de Araraquara (UNIARA) instacron:UNIARA |
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Universidade de Araraquara (UNIARA) |
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UNIARA |
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UNIARA |
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Revista Brasileira Multidisciplinar |
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Revista Brasileira Multidisciplinar |
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Revista Brasileira Multidisciplinar - Universidade de Araraquara (UNIARA) |
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revistauniara@uniara.com|| |
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1797174604354027520 |