Pain behavior to electroacupuncture in rabbit tooth pulp
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian journal of oral sciences (Online) |
Texto Completo: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717 |
Resumo: | Aim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses, f1=2 Hz, f2=0.1 s, 3 mA) was applied in acupoints and sham points, before and during the NT. After 120 min, EACP was withdrawn and the nociceptive threshold was measured every 10 min until the initial nociceptive threshold was achieved. Results: EACP, using the Yintang, ST4 and ST5 acupoints, induced an increased in the nociceptive threshold and this effect persisted for up to 2 h, even after the removal of electric stimulation. Application of EACP at sham points did not show significant analgesic activity. The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. Conclusions: EACP presented an analgesic effect in a rabbit tooth pulp assay that was probably due to the release of endogenous opioids. The duration of this analgesic effect seems to be different for males and females. |
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oai:ojs.periodicos.sbu.unicamp.br:article/8641717 |
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UNICAMP-8 |
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Brazilian journal of oral sciences (Online) |
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Pain behavior to electroacupuncture in rabbit tooth pulpElectroacupunctureTooth pulpAnalgesic effectEndogenous opioidsPainOdontologyAim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses, f1=2 Hz, f2=0.1 s, 3 mA) was applied in acupoints and sham points, before and during the NT. After 120 min, EACP was withdrawn and the nociceptive threshold was measured every 10 min until the initial nociceptive threshold was achieved. Results: EACP, using the Yintang, ST4 and ST5 acupoints, induced an increased in the nociceptive threshold and this effect persisted for up to 2 h, even after the removal of electric stimulation. Application of EACP at sham points did not show significant analgesic activity. The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. Conclusions: EACP presented an analgesic effect in a rabbit tooth pulp assay that was probably due to the release of endogenous opioids. The duration of this analgesic effect seems to be different for males and females.Universidade Estadual de Campinas2015-11-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/864171710.20396/bjos.v9i4.8641717Brazilian Journal of Oral Sciences; v. 9 n. 4 (2010): Oct./Dec.; 415-420Brazilian Journal of Oral Sciences; Vol. 9 No. 4 (2010): Oct./Dec.; 415-4201677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717/9215Gondim, Delane VianaCarvalho, Krishnamurti de MoraisVale, Mariana Limainfo:eu-repo/semantics/openAccess2016-02-25T09:12:14Zoai:ojs.periodicos.sbu.unicamp.br:article/8641717Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2016-02-25T09:12:14Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
dc.title.none.fl_str_mv |
Pain behavior to electroacupuncture in rabbit tooth pulp |
title |
Pain behavior to electroacupuncture in rabbit tooth pulp |
spellingShingle |
Pain behavior to electroacupuncture in rabbit tooth pulp Gondim, Delane Viana Electroacupuncture Tooth pulp Analgesic effect Endogenous opioids Pain Odontology |
title_short |
Pain behavior to electroacupuncture in rabbit tooth pulp |
title_full |
Pain behavior to electroacupuncture in rabbit tooth pulp |
title_fullStr |
Pain behavior to electroacupuncture in rabbit tooth pulp |
title_full_unstemmed |
Pain behavior to electroacupuncture in rabbit tooth pulp |
title_sort |
Pain behavior to electroacupuncture in rabbit tooth pulp |
author |
Gondim, Delane Viana |
author_facet |
Gondim, Delane Viana Carvalho, Krishnamurti de Morais Vale, Mariana Lima |
author_role |
author |
author2 |
Carvalho, Krishnamurti de Morais Vale, Mariana Lima |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Gondim, Delane Viana Carvalho, Krishnamurti de Morais Vale, Mariana Lima |
dc.subject.por.fl_str_mv |
Electroacupuncture Tooth pulp Analgesic effect Endogenous opioids Pain Odontology |
topic |
Electroacupuncture Tooth pulp Analgesic effect Endogenous opioids Pain Odontology |
description |
Aim: The aim of this study was to verify the pain behavior to electroacupuncture (EACP) in rabbit tooth-pulp assay. Methods: Albino rabbits weighing 1.5-2.0 kg) were pretreated with saline or morphine (5mg/kg, e.v.) 10 min before the nociceptive test (NT). In another group, EACP (rectangular pulses, f1=2 Hz, f2=0.1 s, 3 mA) was applied in acupoints and sham points, before and during the NT. After 120 min, EACP was withdrawn and the nociceptive threshold was measured every 10 min until the initial nociceptive threshold was achieved. Results: EACP, using the Yintang, ST4 and ST5 acupoints, induced an increased in the nociceptive threshold and this effect persisted for up to 2 h, even after the removal of electric stimulation. Application of EACP at sham points did not show significant analgesic activity. The present results demonstrated that males presented a higher initial level of analgesia, but a poorer maintenance of analgesic effect after the EACP procedure, while females demonstrated a long lasting analgesic effect even after discontinuation of EACP. Conclusions: EACP presented an analgesic effect in a rabbit tooth pulp assay that was probably due to the release of endogenous opioids. The duration of this analgesic effect seems to be different for males and females. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717 10.20396/bjos.v9i4.8641717 |
url |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717 |
identifier_str_mv |
10.20396/bjos.v9i4.8641717 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8641717/9215 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Oral Sciences; v. 9 n. 4 (2010): Oct./Dec.; 415-420 Brazilian Journal of Oral Sciences; Vol. 9 No. 4 (2010): Oct./Dec.; 415-420 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
instname_str |
Universidade Estadual de Campinas (UNICAMP) |
instacron_str |
UNICAMP |
institution |
UNICAMP |
reponame_str |
Brazilian journal of oral sciences (Online) |
collection |
Brazilian journal of oral sciences (Online) |
repository.name.fl_str_mv |
Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
repository.mail.fl_str_mv |
brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
_version_ |
1800216399515222016 |