Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis

Detalhes bibliográficos
Autor(a) principal: Camargo, Gabriela Alessandra Da Cruz Galhardo
Data de Publicação: 2017
Outros Autores: Silva, Natalia Linhares Coutinho, Miranda, Ana Luísa Palhares de, Tributino, Jorge Luiz Mendonça, Colombo, Natália Helena, Duque, Cristiane
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian journal of oral sciences (Online)
Texto Completo: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993
Resumo: This study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients.
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spelling Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitisDiabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase.PeriodontopathogensThis study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients.Universidade Estadual de Campinas2017-08-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/864999310.20396/bjos.v15i3.8649993Brazilian Journal of Oral Sciences; v. 15 n. 3 (2016): Jul./Sep.; 226-233Brazilian Journal of Oral Sciences; Vol. 15 No. 3 (2016): Jul./Sep.; 226-2331677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPporhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993/16476Camargo, Gabriela Alessandra Da Cruz GalhardoSilva, Natalia Linhares CoutinhoMiranda, Ana Luísa Palhares deTributino, Jorge Luiz MendonçaColombo, Natália HelenaDuque, Cristianeinfo:eu-repo/semantics/openAccess2018-04-03T11:20:01Zoai:ojs.periodicos.sbu.unicamp.br:article/8649993Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2018-04-03T11:20:01Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
title Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
spellingShingle Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
Camargo, Gabriela Alessandra Da Cruz Galhardo
Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase.
Periodontopathogens
title_short Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
title_full Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
title_fullStr Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
title_full_unstemmed Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
title_sort Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
author Camargo, Gabriela Alessandra Da Cruz Galhardo
author_facet Camargo, Gabriela Alessandra Da Cruz Galhardo
Silva, Natalia Linhares Coutinho
Miranda, Ana Luísa Palhares de
Tributino, Jorge Luiz Mendonça
Colombo, Natália Helena
Duque, Cristiane
author_role author
author2 Silva, Natalia Linhares Coutinho
Miranda, Ana Luísa Palhares de
Tributino, Jorge Luiz Mendonça
Colombo, Natália Helena
Duque, Cristiane
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Camargo, Gabriela Alessandra Da Cruz Galhardo
Silva, Natalia Linhares Coutinho
Miranda, Ana Luísa Palhares de
Tributino, Jorge Luiz Mendonça
Colombo, Natália Helena
Duque, Cristiane
dc.subject.por.fl_str_mv Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase.
Periodontopathogens
topic Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase.
Periodontopathogens
description This study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients.
publishDate 2017
dc.date.none.fl_str_mv 2017-08-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/other
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993
10.20396/bjos.v15i3.8649993
url https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993
identifier_str_mv 10.20396/bjos.v15i3.8649993
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993/16476
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Estadual de Campinas
publisher.none.fl_str_mv Universidade Estadual de Campinas
dc.source.none.fl_str_mv Brazilian Journal of Oral Sciences; v. 15 n. 3 (2016): Jul./Sep.; 226-233
Brazilian Journal of Oral Sciences; Vol. 15 No. 3 (2016): Jul./Sep.; 226-233
1677-3225
reponame:Brazilian journal of oral sciences (Online)
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Brazilian journal of oral sciences (Online)
collection Brazilian journal of oral sciences (Online)
repository.name.fl_str_mv Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv brjorals@fop.unicamp.br||brjorals@fop.unicamp.br
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