Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Brazilian journal of oral sciences (Online) |
Texto Completo: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993 |
Resumo: | This study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients. |
id |
UNICAMP-8_7f5480af32f43258b833c9fcae1c292f |
---|---|
oai_identifier_str |
oai:ojs.periodicos.sbu.unicamp.br:article/8649993 |
network_acronym_str |
UNICAMP-8 |
network_name_str |
Brazilian journal of oral sciences (Online) |
repository_id_str |
|
spelling |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitisDiabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase.PeriodontopathogensThis study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients.Universidade Estadual de Campinas2017-08-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/864999310.20396/bjos.v15i3.8649993Brazilian Journal of Oral Sciences; v. 15 n. 3 (2016): Jul./Sep.; 226-233Brazilian Journal of Oral Sciences; Vol. 15 No. 3 (2016): Jul./Sep.; 226-2331677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPporhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993/16476Camargo, Gabriela Alessandra Da Cruz GalhardoSilva, Natalia Linhares CoutinhoMiranda, Ana Luísa Palhares deTributino, Jorge Luiz MendonçaColombo, Natália HelenaDuque, Cristianeinfo:eu-repo/semantics/openAccess2018-04-03T11:20:01Zoai:ojs.periodicos.sbu.unicamp.br:article/8649993Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2018-04-03T11:20:01Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
dc.title.none.fl_str_mv |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
title |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
spellingShingle |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis Camargo, Gabriela Alessandra Da Cruz Galhardo Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase. Periodontopathogens |
title_short |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
title_full |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
title_fullStr |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
title_full_unstemmed |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
title_sort |
Periodontopathogens, Candida spp. and immunological aspects in type 2 diabetes mellitus patients with chronic periodontitis |
author |
Camargo, Gabriela Alessandra Da Cruz Galhardo |
author_facet |
Camargo, Gabriela Alessandra Da Cruz Galhardo Silva, Natalia Linhares Coutinho Miranda, Ana Luísa Palhares de Tributino, Jorge Luiz Mendonça Colombo, Natália Helena Duque, Cristiane |
author_role |
author |
author2 |
Silva, Natalia Linhares Coutinho Miranda, Ana Luísa Palhares de Tributino, Jorge Luiz Mendonça Colombo, Natália Helena Duque, Cristiane |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Camargo, Gabriela Alessandra Da Cruz Galhardo Silva, Natalia Linhares Coutinho Miranda, Ana Luísa Palhares de Tributino, Jorge Luiz Mendonça Colombo, Natália Helena Duque, Cristiane |
dc.subject.por.fl_str_mv |
Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase. Periodontopathogens |
topic |
Diabetes mellitus. Periodontal disease. Candida spp. TNF-α. Myeloperoxidase. Periodontopathogens |
description |
This study aimed to evaluate clinical, microbiological and immunological parameters in type 2 diabetes mellitus (DM) in comparison with normoglycemic patients (NDM). Glycemic and lipid profiles and periodontal clinical status were determined for thirty-three patients (17 DM and 16 NDM). The presence of periodontopathogens and species of Candida in subgingival sites were determined by polymerase chain reaction and immunological parameters by ELISA assays. All glycemic and clinical parameters evaluated were higher in the DM group, with statistical difference for fasting glucose, glycated-hemoglobin, and periodontal parameters. Lipid profile (except triglycerides), levels of TNF-α and myeloperoxidase and the prevalence of the tested microorganisms were similar between the groups, except for Candida albicans and Candida glabrata, which was higher in the DM group. In conclusion, although microbiological and immunological parameters were similar in the DM and NDM groups, periodontitis and the levels of some species of Candida were more severe in DM patients. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-08-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993 10.20396/bjos.v15i3.8649993 |
url |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993 |
identifier_str_mv |
10.20396/bjos.v15i3.8649993 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8649993/16476 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Oral Sciences; v. 15 n. 3 (2016): Jul./Sep.; 226-233 Brazilian Journal of Oral Sciences; Vol. 15 No. 3 (2016): Jul./Sep.; 226-233 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
instname_str |
Universidade Estadual de Campinas (UNICAMP) |
instacron_str |
UNICAMP |
institution |
UNICAMP |
reponame_str |
Brazilian journal of oral sciences (Online) |
collection |
Brazilian journal of oral sciences (Online) |
repository.name.fl_str_mv |
Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
repository.mail.fl_str_mv |
brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
_version_ |
1800216401750786048 |